3-[(2R)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a Potent and Orally Active Antagonist of the Human Gonadotropin-Releasing Hormone Receptor. Design, Synthesis, and in Vitro and in Vivo Characterization

2005 ◽  
Vol 48 (4) ◽  
pp. 1169-1178 ◽  
Author(s):  
Fabio C. Tucci ◽  
Yun-Fei Zhu ◽  
R. Scott Struthers ◽  
Zhiqiang Guo ◽  
Timothy D. Gross ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Gonadotropin Releasing Hormone ◽  
Design Synthesis ◽  
Releasing Hormone ◽  
Receptor Design ◽  
In Vivo Characterization ◽  
Gonadotropin Releasing Hormone Receptor ◽  
Orally Active

scholarly journals Gonadotropin-Releasing Hormone Receptor Levels and Cell Context Affect Tumor Cell Responses to Agonist In vitro and In vivo

2008 ◽  
Vol 68 (15) ◽  
pp. 6331-6340 ◽  
Author(s):  
Kevin Morgan ◽  
Alan J. Stewart ◽  
Nicola Miller ◽  
Peter Mullen ◽  
Morwenna Muir ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Hormone Receptor ◽  
Gonadotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Cell Responses ◽  
Gonadotropin Releasing Hormone Receptor
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