Synthesis and Biological Evaluation of 11-Substituted 6-Aminobenzo[c]phenanthridine Derivatives, a New Class of Antitumor Agents

2005 ◽  
Vol 48 (8) ◽  
pp. 2772-2777 ◽  
Author(s):  
Ilka Kock ◽  
Dieter Heber ◽  
Matthias Weide ◽  
Ulrich Wolschendorf ◽  
Bernd Clement
Keyword(s):  
Antitumor Agents ◽  
Biological Evaluation ◽  
New Class ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of indazolo[4,3-bc][1,5]naphthyridines (10-aza-pyrazolo[3,4,5-kl]acridines): a new class of antitumor agents

2004 ◽  
Vol 12 (22) ◽  
pp. 5941-5947 ◽  
Author(s):  
Amelia Magnano ◽  
Silvia Sparapani ◽  
Roberta Lucciarini ◽  
Mosca Michela ◽  
Consuelo Amantini ◽  
...  
Keyword(s):  
Antitumor Agents ◽  
Biological Evaluation ◽  
New Class ◽  
Synthesis And Biological Evaluation

Design, synthesis and biological evaluation of C(6)-indole celastrol derivatives as potential antitumor agents

RSC Advances ◽  
2015 ◽  
Vol 5 (25) ◽  
pp. 19620-19623 ◽  
Author(s):  
Kaiyong Tang ◽  
Jinwen Huang ◽  
Junfang Pan ◽  
Xuan Zhang ◽  
Wei Lu
Keyword(s):  
Cancer Cells ◽  
Antitumor Agents ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
New Class ◽  
Synthesis And Biological Evaluation ◽  
Antiproliferative Activities ◽  
Potential Antitumor

A new class of C(6)-indole substituted celastrol derivatives were designed and synthesized. Among all these synthesized molecules, compound 4f and 4h displayed excellent in vitro antiproliferative activities against Bel7402 cancer cells.

Rational design, synthesis and biological evaluation of thiadiazinoacridines: A new class of antitumor agents

2003 ◽  
Vol 11 (3) ◽  
pp. 399-405 ◽  
Author(s):  
Ippolito Antonini ◽  
Paolo Polucci ◽  
Amelia Magnano ◽  
Diego Cacciamani ◽  
Marek T Konieczny ◽  
...  
Keyword(s):  
Rational Design ◽  
Antitumor Agents ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
New Class ◽  
Synthesis And Biological Evaluation

Synthesis and Biological Evaluation of Diaryl Ether Linked DC-81 Conjugates as Potential Antitumor Agents

2013 ◽  
Vol 13 (10) ◽  
pp. 1590-1600 ◽  
Author(s):  
Ahmed Kamal ◽  
A. Viswanath ◽  
M. Ramaiah ◽  
J. Murty ◽  
Farheen Sultana ◽  
...  
Keyword(s):  
Antitumor Agents ◽  
Biological Evaluation ◽  
Diaryl Ether ◽  
Synthesis And Biological Evaluation ◽  
Potential Antitumor
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