Novel Retinoic Acid Metabolism Blocking Agents Endowed with Multiple Biological Activities Are Efficient Growth Inhibitors of Human Breast and Prostate Cancer Cells in Vitro and a Human Breast Tumor Xenograft in Nude Mice

2004 ◽  
Vol 47 (27) ◽  
pp. 6716-6729 ◽  
Author(s):  
Jyoti B. Patel ◽  
Carlic K. Huynh ◽  
Venkatesh D. Handratta ◽  
Lalji K. Gediya ◽  
Angela M. H. Brodie ◽  
...  
Keyword(s):  
Breast Tumor ◽  
Acid Metabolism ◽  
Biological Activities ◽  
Tumor Xenograft ◽  
Growth Inhibitors ◽  
Human Breast ◽  
Prostate Cancer Cells ◽  
Human Breast Tumor ◽  
Breast And Prostate Cancer

scholarly journals Essential Oil Constituents and Biological Activities of Peristrophe Bicalyculata and Borreria verticillata

2010 ◽  
Vol 5 (11) ◽  
pp. 1934578X1000501 ◽  
Author(s):  
Isiaka A. Ogunwande ◽  
Tameka M. Walker ◽  
Anita Bansal ◽  
William N. Setzer ◽  
Emmanuel E. Essien
Keyword(s):  
Breast Tumor ◽  
Biological Activities ◽  
Volatile Oil ◽  
In Vitro Cytotoxicity ◽  
Gas Chromatography Mass Spectrometry ◽  
Human Breast ◽  
Volatile Oils ◽  
Human Breast Tumor ◽  
Peristrophe Bicalyculata

Peristrophe bicalyculata (Retz) Nees (Acanthaceae) or ‘The Goddess of Mercy’ and Borreria verticillata (L.) G.F.W. Mey., (Rubiaceae), or ‘Irawo-Ile’ (Yoruba, South-west, Nigeria), are annual herbs, which are poorly exploited. The volatile oils obtained by hydrodistillation in an all glass Clevenger-type apparatus from the plant samples have been investigated by gas chromatography-mass spectrometry (GC-MS). With respect to the oil of P. bicalyculata, β-caryophyllene (33.9%), α-zingiberene (10.4%), germacrene D and globulol (5.0%) were the compounds occurring in abundance. The oil of B. verticillata had an abundance of phytol (56.3%) and 1, 8-cineole (20.4%), with sizeable proportions of α-pinene (7.1%) and p-cymene (4.0%). In addition, the volatile oils displayed promising in-vitro antimicrobial activity against the tested micro-organisms, (MIC 12.5-22.3 μg/mL), while only the oil of P. bicalyculata displayed in-vitro cytotoxicity to MCF-7 (human breast tumor) and MDA-MB-468 (human breast tumor) cells. The present investigation may be the first of its kind for the evaluation of the volatile oil constituents of the studied plants.

2-Methoxyestradiol reverses doxorubicin resistance in human breast tumor xenograft

2008 ◽  
Vol 62 (5) ◽  
pp. 893-902 ◽  
Author(s):  
Samar S. Azab ◽  
Salama A. Salama ◽  
Memy H. Hassan ◽  
Amani E. Khalifa ◽  
Ebtehal El-Demerdash ◽  
...  
Keyword(s):  
Breast Tumor ◽  
Tumor Xenograft ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Doxorubicin Resistance

Tumor cell-specific loss of p53 protein in a unique in vitro model of human breast tumor progression

1994 ◽  
Vol 15 (9) ◽  
pp. 1969-1973 ◽  
Author(s):  
Xiao-Long Liu ◽  
Hamid Band ◽  
Qingshen Gao ◽  
David E. Wazer ◽  
Quiming Chu ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Breast Tumor ◽  
In Vitro Model ◽  
P53 Protein ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Specific Loss ◽  
Vitro Model ◽  
Breast Tumor Progression

scholarly journals Chemical Compositions and Biological Activities of Leaf Essential Oils of Twelve Species of Piper from Monteverde, Costa Rica

2008 ◽  
Vol 3 (8) ◽  
pp. 1934578X0800300 ◽  
Author(s):  
William N. Setzer ◽  
Grace Park ◽  
Brittany R. Agius ◽  
Sean L. Stokes ◽  
Tameka M. Walker ◽  
...  
Keyword(s):  
Costa Rica ◽  
Essential Oils ◽  
Biological Activities ◽  
Artemia Salina ◽  
Chemical Compositions ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Leaf Oil ◽  
Mcf 7

The leaf essential oils of twelve species of Piper (Piperaceae) from Monteverde, Costa Rica ( Piper aequale, Piper amalago, Piper biasperatum, Piper bredemeyeri, Piper dotanum, Piper fimbriulatum, Piper glabrescens, Piper imperiale, Piper lanceifolium, Piper nemorense, Piper oblanceolatum, and Piper sp. A near aereum) have been obtained by hydrodistillation and analyzed by GC-MS. The Piper leaf oils have been screened for antibacterial activity against Bacillus cereus, Staphylococcus aureus, and Escherichia coli; for Artemia salina (brine shrimp) lethality; for in-vitro cytotoxic activity against MCF-7 (human breast tumor) cells; and inhibition of the cysteine protease cruzain. A cluster analysis comparison with previously published Piper leaf oil compositions was carried out in order to discern the differences and similarities between the volatile chemical compositions of Piper species.

scholarly journals Combined MR, fluorescence and histology imaging strategy in a human breast tumor xenograft model

2012 ◽  
Vol 26 (3) ◽  
pp. 285-298 ◽  
Author(s):  
Lu Jiang ◽  
Tiffany R. Greenwood ◽  
Erika R. Amstalden van Hove ◽  
Kamila Chughtai ◽  
Venu Raman ◽  
...  
Keyword(s):  
Breast Tumor ◽  
Xenograft Model ◽  
Tumor Xenograft ◽  
Human Breast ◽  
Human Breast Tumor ◽  
Imaging Strategy

scholarly journals Anticancer activity of a sub-fraction of dichloromethane extract of Strobilanthes crispus on human breast and prostate cancer cells in vitro

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Nik Soriani Yaacob ◽  
Nurraihana Hamzah ◽  
Nik Nursyazni Nik Mohamed Kamal ◽  
Siti Amalina Zainal Abidin ◽  
Choon Sheen Lai ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Human Breast ◽  
Prostate Cancer Cells ◽  
Strobilanthes Crispus ◽  
Breast And Prostate Cancer
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