Design, Synthesis, and in Vitro Evaluation of Dipeptide-Based Antibody Minor Groove Binder Conjugates

2005 ◽  
Vol 48 (5) ◽  
pp. 1344-1358 ◽  
Author(s):  
Scott C. Jeffrey ◽  
Michael Y. Torgov ◽  
Jamie B. Andreyka ◽  
Laura Boddington ◽  
Charles G. Cerveny ◽  
...  
Keyword(s):  
Minor Groove ◽  
Minor Groove Binder ◽  
Design Synthesis ◽  
In Vitro Evaluation

Design, Synthesis and in vitro Cytotoxicity of a cis-Dichloroplatinum (II) Complex Linked to the Minor Groove Binder Stallimycin

2011 ◽  
Vol 53 (02) ◽  
pp. 107-113
Author(s):  
Pier Baraldi ◽  
Mojgan Tabrizi ◽  
Maria Pavani ◽  
Maria Nuñez ◽  
Rimma Makaeva ◽  
...  
Keyword(s):  
Minor Groove ◽  
In Vitro Cytotoxicity ◽  
Minor Groove Binder ◽  
Design Synthesis

scholarly journals Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

2021 ◽  
Vol 36 (1) ◽  
pp. 1370-1377
Author(s):  
Daniel A. S. Kitagawa ◽  
Rafael B. Rodrigues ◽  
Thiago N. Silva ◽  
Wellington V. dos Santos ◽  
Vinicius C. V. da Rocha ◽  
...  
Keyword(s):  
In Silico ◽  
Design Synthesis ◽  
In Vitro Evaluation ◽  
In Silico Studies ◽  
Acetylcholinesterase Reactivators

Design, Synthesis, and In Vitro Evaluation of Tubulin‐targeting Dibenzothiazines with Antiproliferative Activity as Novel Heterocycle Building Block

ChemMedChem ◽  
2021 ◽  
Author(s):  
Walter Damián Guerra ◽  
Daniel Lucena-Agell ◽  
Rafael Hortigüela ◽  
Roberto Arturo Rossi ◽  
J. Fernando Díaz ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Building Block ◽  
Design Synthesis ◽  
In Vitro Evaluation

scholarly journals Structure-Based Design, Synthesis, and in vitro Evaluation of Bisubstrate Inhibitors for CatecholO-Methyltransferase (COMT)

2000 ◽  
Vol 6 (6) ◽  
pp. 971-982 ◽  
Author(s):  
Birgit Masjost ◽  
Patrick Ballmer ◽  
Edilio Borroni ◽  
Gerhard Zürcher ◽  
Fritz K. Winkler ◽  
...  
Keyword(s):  
Design Synthesis ◽  
In Vitro Evaluation ◽  
Bisubstrate Inhibitors

Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules

2004 ◽  
Vol 12 (20) ◽  
pp. 5453-5463 ◽  
Author(s):  
Stefano Manfredini ◽  
Silvia Vertuani ◽  
Barbara Pavan ◽  
Federica Vitali ◽  
Martina Scaglianti ◽  
...  
Keyword(s):  
Design Synthesis ◽  
In Vitro Evaluation

Design, synthesis and in vitro evaluation of phenylbenzamidine derivatives as SSRIs

2007 ◽  
Vol 18 (7) ◽  
pp. 814-816 ◽  
Author(s):  
Jing Yang ◽  
Xiaofang Wang ◽  
Hui Wen ◽  
Fang Qin ◽  
Guang Zhong Yang
Keyword(s):  
Design Synthesis ◽  
In Vitro Evaluation

Design, synthesis, in-vitro evaluation and molecular docking studies of novel indole derivatives as inhibitors of SIRT1 and SIRT2

2019 ◽  
Vol 92 ◽  
pp. 103281 ◽  
Author(s):  
Ramu Manjula ◽  
Nikhila Gokhale ◽  
Sruthi Unni ◽  
Prashant Deshmukh ◽  
Rajkumar Reddyrajula ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Indole Derivatives ◽  
Design Synthesis ◽  
In Vitro Evaluation ◽  
Molecular Docking Studies

scholarly journals Design, synthesis and in vitro evaluation against human cancer cells of 5-methyl-5-styryl-2,5-dihydrofuran-2-ones, a new series of goniothalamin analogues

2013 ◽  
Vol 21 (17) ◽  
pp. 5107-5117 ◽  
Author(s):  
Marjorie Bruder ◽  
Débora Barbosa Vendramini-Costa ◽  
João Ernesto de Carvalho ◽  
Ronaldo Aloise Pilli
Keyword(s):  
Cancer Cells ◽  
Human Cancer ◽  
Design Synthesis ◽  
In Vitro Evaluation ◽  
Human Cancer Cells
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