Design and Synthesis of Peptidomimetic Protein Farnesyltransferase Inhibitors as Anti-Trypanosoma bruceiAgents

2004 ◽  
Vol 47 (2) ◽  
pp. 432-445 ◽  
Author(s):  
Junko Ohkanda ◽  
Frederick S. Buckner ◽  
Jeffrey W. Lockman ◽  
Kohei Yokoyama ◽  
Dora Carrico ◽  
...  
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Protein Farnesyltransferase ◽  
Design And Synthesis

Protein Farnesyltransferase Inhibitors

2004 ◽  
Vol 1 (1) ◽  
pp. 97-128
Author(s):  
Semiramis Ayral-Kaloustian ◽  
Edward J. Salaski
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Protein Farnesyltransferase

Design and Synthesis of Non-Peptide Ras CAAX Mimetics as Potent Farnesyltransferase Inhibitors

1996 ◽  
Vol 39 (1) ◽  
pp. 217-223 ◽  
Author(s):  
Yimin Qian ◽  
Andreas Vogt ◽  
Saïd M. Sebti ◽  
Andrew D. Hamilton
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Design And Synthesis

Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors

2016 ◽  
Vol 109 ◽  
pp. 173-186 ◽  
Author(s):  
Damien Bosc ◽  
Elisabeth Mouray ◽  
Sandrine Cojean ◽  
Caio Haddad Franco ◽  
Philippe M. Loiseau ◽  
...  
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Antiparasitic Activity ◽  
Protein Farnesyltransferase

scholarly journals Structure-Based Design and Synthesis of Potent, Ethylenediamine-Based, Mammalian Farnesyltransferase Inhibitors as Anticancer Agents

2010 ◽  
Vol 53 (19) ◽  
pp. 6867-6888 ◽  
Author(s):  
Steven Fletcher ◽  
Erin Pusateri Keaney ◽  
Christopher G. Cummings ◽  
Michelle A. Blaskovich ◽  
Michael A. Hast ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Farnesyltransferase Inhibitors ◽  
Design And Synthesis

The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth

1998 ◽  
Vol 94 (1) ◽  
pp. 87-97 ◽  
Author(s):  
Kohei Yokoyama ◽  
Patty Trobridge ◽  
Frederick S Buckner ◽  
Jeffrey Scholten ◽  
Kenneth D Stuart ◽  
...  
Keyword(s):  
Cell Growth ◽  
Farnesyltransferase Inhibitors ◽  
Protein Farnesyltransferase

scholarly journals Second Generation Tetrahydroquinoline-Based Protein Farnesyltransferase Inhibitors as Antimalarials

2007 ◽  
Vol 50 (19) ◽  
pp. 4585-4605 ◽  
Author(s):  
Pravin Bendale ◽  
Srinivas Olepu ◽  
Praveen Kumar Suryadevara ◽  
Vivek Bulbule ◽  
Kasey Rivas ◽  
...  
Keyword(s):  
Second Generation ◽  
Farnesyltransferase Inhibitors ◽  
Protein Farnesyltransferase
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