Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 17. Highly δ Opioid Receptor Selective 14-Alkoxy-Substituted Indolo- and Benzofuromorphinans

Johannes Schütz; Christina M. Dersch; Robert Horel; Mariana Spetea; Martin Koch; Ruth Meditz; Elisabeth Greiner; Richard B. Rothman; Helmut Schmidhammer

doi:10.1021/jm020940p

Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 17. Highly δ Opioid Receptor Selective 14-Alkoxy-Substituted Indolo- and Benzofuromorphinans

Journal of Medicinal Chemistry ◽

10.1021/jm020940p ◽

2002 ◽

Vol 45 (24) ◽

pp. 5378-5383 ◽

Cited By ~ 17

Author(s):

Johannes Schütz ◽

Christina M. Dersch ◽

Robert Horel ◽

Mariana Spetea ◽

Martin Koch ◽

...

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Δ Opioid Receptor ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of 14-alkoxymorphinans. 14.1 14-ethoxy-5-methyl substituted indolomorphinans with δ opioid receptor selectivity

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(96)00599-9 ◽

1997 ◽

Vol 7 (2) ◽

pp. 151-156 ◽

Cited By ~ 9

Author(s):

Helmut Schmidhammer ◽

Dietmar Daurer ◽

Martina Wieser ◽

Krisztina Monory ◽

Anna Borsodi ◽

...

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Receptor Selectivity ◽

Δ Opioid Receptor ◽

Synthesis And Biological Evaluation ◽

Opioid Receptor Selectivity

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Synthesis and biological evaluation of novel delta (δ) opioid receptor ligands with diazatricyclodecane skeletons

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2013.09.014 ◽

2013 ◽

Vol 69 ◽

pp. 413-426 ◽

Cited By ~ 5

Author(s):

Giovanni Loriga ◽

Paolo Lazzari ◽

Stefania Ruiu ◽

Giorgio Marchese ◽

Ilaria Manca ◽

...

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Receptor Ligands ◽

Opioid Receptor Ligands ◽

Δ Opioid Receptor ◽

Synthesis And Biological Evaluation

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ChemInform Abstract: Probes for Narcotic Receptor Mediated Phenomena. Part 26. Synthesis and Biological Evaluation of Diarylmethylpiperazines and Diarylmethylpiperidines as Novel, Nonpeptidic δ Opioid Receptor Ligands.

ChemInform ◽

10.1002/chin.200013125 ◽

2010 ◽

Vol 31 (13) ◽

pp. no-no

Author(s):

Kenner C. Rice ◽

et al. et al.

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Receptor Ligands ◽

Opioid Receptor Ligands ◽

Δ Opioid Receptor ◽

Synthesis And Biological Evaluation

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ChemInform Abstract: Synthesis and Biological Evaluation of 14-Alkoxymorphinans. Part 15. Novel δ Opioid Receptor Antagonists with High Affinity and Selectivity in the 14-Alkoxy-Substituted Indolomorphinan Series.

ChemInform ◽

10.1002/chin.199834258 ◽

2010 ◽

Vol 29 (34) ◽

pp. no-no

Author(s):

H. SCHMIDHAMMER ◽

R. KRASSNIG ◽

E. GREINER ◽

J. SCHUETZ ◽

A. WHITE ◽

...

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

High Affinity ◽

Opioid Receptor Antagonists ◽

Δ Opioid Receptor ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel tetrahydroisoquinoline quaternary derivatives as peripheral κ-opioid receptor agonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2016.05.002 ◽

2016 ◽

Vol 24 (13) ◽

pp. 2964-2970 ◽

Cited By ~ 7

Author(s):

Ting Guo ◽

Zongjie Gan ◽

Jie Chen ◽

Dechuan Wang ◽

Ling He ◽

...

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Design Synthesis ◽

Receptor Agonists ◽

Opioid Receptor Agonists ◽

Synthesis And Biological Evaluation

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Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 16. 14-O-Alkyl Derivatives of the m-Opioid Receptor Antagonist Cyprodime

Heterocycles ◽

10.3987/com-98-s60 ◽

1998 ◽

Vol 49 (1) ◽

pp. 489 ◽

Cited By ~ 5

Author(s):

Helmut Schmidhammer ◽

Roland Krassnig ◽

Elisabeth Greiner ◽

John R. Traynor

Keyword(s):

Receptor Antagonist ◽

Opioid Receptor ◽

Biological Evaluation ◽

Opioid Receptor Antagonist ◽

Alkyl Derivatives ◽

Synthesis And Biological Evaluation ◽

Derivatives Of

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Design, synthesis and biological evaluation of N-hydroxy-aminobenzyloxyarylamide analogues as novel selective κ opioid receptor antagonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2020.127236 ◽

2020 ◽

Vol 30 (13) ◽

pp. 127236

Author(s):

Guangchao He ◽

Qiao Song ◽

Junwei Wang ◽

Anhua Xu ◽

Kewen Peng ◽

...

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Opioid Receptor Antagonists ◽

Synthesis And Biological Evaluation

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Design, Synthesis, and Biological Evaluation of Novel Bifunctional C-Terminal-Modified Peptides for δ/μ Opioid Receptor Agonists and Neurokinin-1 Receptor Antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm061369n ◽

2007 ◽

Vol 50 (12) ◽

pp. 2779-2786 ◽

Cited By ~ 40

Author(s):

Takashi Yamamoto ◽

Padma Nair ◽

Peg Davis ◽

Shou-wu Ma ◽

Edita Navratilova ◽

...

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Neurokinin 1 Receptor ◽

Modified Peptides ◽

Μ Opioid Receptor ◽

Neurokinin 1 ◽

Opioid Receptor Agonists ◽

Synthesis And Biological Evaluation

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Corrections to Design, Synthesis, and Biological Evaluation of 6α- and 6β-N-Heterocyclic Substituted Naltrexamine Derivatives as μ Opioid Receptor Selective Antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm9016224 ◽

2009 ◽

Vol 52 (24) ◽

pp. 8057-8057 ◽

Cited By ~ 1

Author(s):

Guo Li ◽

Lindsey C. Aschenbach ◽

Jianyang Chen ◽

Michael P. Cassidy ◽

David L. Stevens ◽

...

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Design Synthesis ◽

Selective Antagonists ◽

Μ Opioid Receptor ◽

Synthesis And Biological Evaluation

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Synthesis and Biological Evaluation of 14-Alkoxymorphinans. Part 19. Effect of 14-O-Benzylation on the Opioid Receptor Affinity and Antagonist Potency of Naltrexone.

ChemInform ◽

10.1002/chin.200341152 ◽

2003 ◽

Vol 34 (41) ◽

Author(s):

Falko Schuellner ◽

Ruth Meditz ◽

Roland Krassing ◽

Guenther Morandell ◽

Valery N. Kalinin ◽

...

Keyword(s):

Opioid Receptor ◽

Biological Evaluation ◽

Receptor Affinity ◽

Synthesis And Biological Evaluation

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