Synthesis and Molecular Modeling of New 1-Aryl-3-[4-arylpiperazin-1-yl]-1-propane Derivatives with High Affinity at the Serotonin Transporter and at 5-HT1AReceptors

2002 ◽  
Vol 45 (19) ◽  
pp. 4128-4139 ◽  
Author(s):  
Lara Orús ◽  
Silvia Pérez-Silanes ◽  
Ana-M. Oficialdegui ◽  
Javier Martínez-Esparza ◽  
Juan-C Del Castillo ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Serotonin Transporter ◽  
High Affinity

Molecular Modeling Studies Focused on 5-HT7versus 5-HT1ASelectivity. Discovery of Novel Phenylpyrrole Derivatives with High Affinity for 5-HT7Receptors

2005 ◽  
Vol 45 (4) ◽  
pp. 1075-1081 ◽  
Author(s):  
Alban Lepailleur ◽  
Ronan Bureau ◽  
Magalie Paillet-Loilier ◽  
Frédéric Fabis ◽  
Nicolas Saettel ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
High Affinity ◽  
Modeling Studies ◽  
Molecular Modeling Studies

3β-(4-Ethyl-3-iodophenyl)nortropane-2β- carboxylic Acid Methyl Ester as a High-Affinity Selective Ligand for the Serotonin Transporter

1997 ◽  
Vol 40 (24) ◽  
pp. 3861-3864 ◽  
Author(s):  
Bruce E. Blough ◽  
Philip Abraham ◽  
Andrew C. Mills ◽  
Anita H. Lewin ◽  
John W. Boja ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Methyl Ester ◽  
Serotonin Transporter ◽  
Acid Methyl Ester ◽  
High Affinity ◽  
Acid Methyl ◽  
Selective Ligand

Binding of Serotonin to the Human Serotonin Transporter. Molecular Modeling and Experimental Validation

2008 ◽  
Vol 130 (12) ◽  
pp. 3853-3865 ◽  
Author(s):  
Leyla Celik ◽  
Steffen Sinning ◽  
Kasper Severinsen ◽  
Carsten G. Hansen ◽  
Maria S. Møller ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Serotonin Transporter ◽  
Experimental Validation

scholarly journals Novel and High Affinity Fluorescent Ligands for the Serotonin Transporter Based on (S)-Citalopram

2014 ◽  
Vol 5 (6) ◽  
pp. 696-699 ◽  
Author(s):  
Vivek Kumar ◽  
Troels Rahbek-Clemmensen ◽  
Christian B. Billesbølle ◽  
Trine Nygaard Jorgensen ◽  
Ulrik Gether ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
High Affinity ◽  
Fluorescent Ligands

Structural Studies on McN-5652-X (I), a High-Affinity Ligand for the Serotonin Transporter in Mammalian Brain.

ChemInform ◽  
2003 ◽  
Vol 34 (36) ◽  
Author(s):  
Bruce E. Maryanoff ◽  
David F. McComsey ◽  
Rina K. Dukor ◽  
Laurence A. Nafie ◽  
Teresa B. Freedman ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
Mammalian Brain ◽  
Structural Studies ◽  
High Affinity ◽  
Affinity Ligand ◽  
High Affinity Ligand

scholarly journals The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Per Plenge ◽  
Ara M. Abramyan ◽  
Gunnar Sørensen ◽  
Arne Mørk ◽  
Pia Weikop ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
High Affinity ◽  
Allosteric Inhibitor

Structural studies on McN-5652-X, a high-affinity ligand for the serotonin transporter in mammalian brain

2003 ◽  
Vol 11 (11) ◽  
pp. 2463-2470 ◽  
Author(s):  
Bruce E Maryanoff ◽  
David F McComsey ◽  
Rina K Dukor ◽  
Laurence A Nafie ◽  
Teresa B Freedman ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
Mammalian Brain ◽  
Structural Studies ◽  
High Affinity ◽  
Affinity Ligand ◽  
High Affinity Ligand

scholarly journals Transgenic elimination of high-affinity antidepressant and cocaine sensitivity in the presynaptic serotonin transporter

2011 ◽  
Vol 108 (9) ◽  
pp. 3785-3790 ◽  
Author(s):  
Brent J. Thompson ◽  
Tammy Jessen ◽  
L. K. Henry ◽  
Julie R. Field ◽  
Karen L. Gamble ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
High Affinity
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