Synthesis, binding studies, and structure activity relationships of 1-aryl- and 2-aryl[1]benzopyranopyrazol-4-ones, central benzodiazepine receptor ligands

Vittoria Colotta; Lucia Cecchi; Guido Filacchioni; Fabrizio Melani; Giovanna Palazzino; Claudia Martini; Gino Giannaccini; Antonio Lucacchini

doi:10.1021/jm00396a001

Synthesis, binding studies, and structure activity relationships of 1-aryl- and 2-aryl[1]benzopyranopyrazol-4-ones, central benzodiazepine receptor ligands

Journal of Medicinal Chemistry ◽

10.1021/jm00396a001 ◽

1988 ◽

Vol 31 (1) ◽

pp. 1-3 ◽

Cited By ~ 24

Author(s):

Vittoria Colotta ◽

Lucia Cecchi ◽

Guido Filacchioni ◽

Fabrizio Melani ◽

Giovanna Palazzino ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Ligands ◽

Binding Studies ◽

Benzodiazepine Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity ◽

Central Benzodiazepine Receptor

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ChemInform Abstract: Synthesis, Binding Studies, and Structure-Activity Relationships of 1-Aryl- and 2-Aryl(1)benzopyranopyrazol-4-ones, Central Benzodiazepine Receptor Ligands.

ChemInform ◽

10.1002/chin.198821206 ◽

1988 ◽

Vol 19 (21) ◽

Author(s):

V. COLOTTA ◽

L. CECCHI ◽

G. FILACCHIONI ◽

F. MELANI ◽

G. PALAZZINO ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Ligands ◽

Binding Studies ◽

Benzodiazepine Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity ◽

Central Benzodiazepine Receptor

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Additions and Corrections-Synthesis, Binding Studies, and Structure-Activity Relationships of 1-Aryl- and 2-Aryl[1]benzopyranopyrazol-4-ones, Central Benzodiazepine Receptor Ligands

Journal of Medicinal Chemistry ◽

10.1021/jm00398a600 ◽

1988 ◽

Vol 31 (3) ◽

pp. 700-700

Author(s):

Vittoria Colotta ◽

Lucia Cecchi ◽

Guido Filacchioni ◽

Fabrizio Melani ◽

Giovanna Palazzino ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Ligands ◽

Binding Studies ◽

Benzodiazepine Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity ◽

Central Benzodiazepine Receptor

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Tricyclic heteroaromatic systems. [1]benzopyranopyrrol-4-ones and [1]benzopyrano-1,2,3-triazol-4-ones as benzodiazepine receptor ligands. Synthesis and structure-activity relationships

Journal of Medicinal Chemistry ◽

10.1021/jm00171a047 ◽

1990 ◽

Vol 33 (9) ◽

pp. 2646-2651 ◽

Cited By ~ 29

Author(s):

Vittoria Colotta ◽

Lucia Cecchi ◽

Fabrizio Melani ◽

Guido Filacchioni ◽

Claudia Martini ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Ligands ◽

Benzodiazepine Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity

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High affinity central benzodiazepine receptor ligands. Part 2: quantitative structure–activity relationships and comparative molecular field analysis of pyrazolo[4,3- c ]quinolin-3-ones

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(00)00262-5 ◽

2001 ◽

Vol 9 (2) ◽

pp. 431-444 ◽

Cited By ~ 18

Author(s):

L. Savini ◽

L. Chiasserini ◽

C. Pellerano ◽

G. Biggio ◽

E. Maciocco ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Field Analysis ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Receptor Ligands ◽

Benzodiazepine Receptor Ligands ◽

High Affinity ◽

Structure Activity ◽

Central Benzodiazepine Receptor ◽

Quantitative Structure Activity Relationships

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Synthesis and Structure−Activity Relationships of Fused Imidazopyridines: A New Series of Benzodiazepine Receptor Ligands

Journal of Medicinal Chemistry ◽

10.1021/jm9600609 ◽

1996 ◽

Vol 39 (14) ◽

pp. 2844-2851 ◽

Cited By ~ 17

Author(s):

Susumu Takada ◽

Takashi Sasatani ◽

Nobuo Chomei ◽

Makoto Adachi ◽

Toshio Fujishita ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Ligands ◽

Benzodiazepine Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity

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Structure−Activity Relationships in Carboxamide Derivatives Based on the Targeted Delivery of Radionuclides and Boron Atoms by Means of Peripheral Benzodiazepine Receptor Ligands

Journal of Medicinal Chemistry ◽

10.1021/jm034068b ◽

2003 ◽

Vol 46 (17) ◽

pp. 3568-3571 ◽

Cited By ~ 24

Author(s):

Andrea Cappelli ◽

Gal.la Pericot Mohr ◽

Andrea Gallelli ◽

Germano Giuliani ◽

Maurizio Anzini ◽

...

Keyword(s):

Targeted Delivery ◽

Benzodiazepine Receptor ◽

Peripheral Benzodiazepine Receptor ◽

Receptor Ligands ◽

Benzodiazepine Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity

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Design, synthesis, and structure?activity relationships of novel tetracyclic compounds as peripheral benzodiazepine receptor ligands*1

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(04)00314-1 ◽

2004 ◽

Author(s):

T OKUBO

Keyword(s):

Benzodiazepine Receptor ◽

Peripheral Benzodiazepine Receptor ◽

Receptor Ligands ◽

Design Synthesis ◽

Benzodiazepine Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity

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Design, synthesis, and structure–activity relationships of novel tetracyclic compounds as peripheral benzodiazepine receptor ligands

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2004.04.025 ◽

2004 ◽

Vol 12 (13) ◽

pp. 3569-3580 ◽

Cited By ~ 29

Author(s):

Taketoshi Okubo ◽

Ryoko Yoshikawa ◽

Shigeyuki Chaki ◽

Shigeru Okuyama ◽

Atsuro Nakazato

Keyword(s):

Benzodiazepine Receptor ◽

Peripheral Benzodiazepine Receptor ◽

Receptor Ligands ◽

Design Synthesis ◽

Benzodiazepine Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity

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High affinity central benzodiazepine receptor ligands: synthesis and structure–activity relationship studies of a new series of pyrazolo[4,3- c ]quinolin-3-ones

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(97)10039-6 ◽

1998 ◽

Vol 6 (4) ◽

pp. 389-399 ◽

Cited By ~ 28

Author(s):

L. Savini ◽

P. Massarelli ◽

C. Nencini ◽

C. Pellerano ◽

G. Biggio ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Receptor Ligands ◽

Benzodiazepine Receptor Ligands ◽

High Affinity ◽

Structure Activity ◽

Central Benzodiazepine Receptor

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ChemInform Abstract: Synthesis and Structure-Activity Relationships of Fused Imidazopyridines: A New Series of Benzodiazepine Receptor Ligands.

ChemInform ◽

10.1002/chin.199643122 ◽

2010 ◽

Vol 27 (43) ◽

pp. no-no

Author(s):

S. TAKADA ◽

T. SASATANI ◽

N. CHOMEI ◽

M. ADACHI ◽

T. FUJISHITA ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Receptor Ligands ◽

Benzodiazepine Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text