.gamma.-Aminobutyric acid esters. 3. Synthesis, brain uptake, and pharmacological properties of C-18 glyceryl lipid esters of GABA with varying degree of unsaturation

1987 ◽  
Vol 30 (9) ◽  
pp. 1573-1576 ◽  
Author(s):  
James N. Jacob ◽  
Gary W. Hesse ◽  
Victor E. Shashoua
Keyword(s):  
Aminobutyric Acid ◽  
Brain Uptake ◽  
Pharmacological Properties ◽  
Gamma Aminobutyric Acid ◽  
Degree Of Unsaturation ◽  
Acid Esters

.gamma.-Aminobutyric acid esters. I. Synthesis, brain uptake, and pharmacological studies of aliphatic and steroid esters of .gamma.-aminobutyric acid

1984 ◽  
Vol 27 (5) ◽  
pp. 659-664 ◽  
Author(s):  
Victor E. Shashoua ◽  
James N. Jacob ◽  
Richard Ridge ◽  
Alexander Campbell ◽  
Ross J. Baldessarini
Keyword(s):  
Aminobutyric Acid ◽  
Brain Uptake ◽  
Gamma Aminobutyric Acid ◽  
Pharmacological Studies ◽  
Acid Esters

Purification of Antihemophilic Factor (Factor VIII) by Amino Acid Precipitation*

1964 ◽  
Vol 11 (01) ◽  
pp. 064-074 ◽  
Author(s):  
Robert H Wagner ◽  
William D McLester ◽  
Marion Smith ◽  
K. M Brinkhous
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Factor Viii ◽  
Plasma Protein ◽  
Acid Precipitation ◽  
Aminobutyric Acid ◽  
Gamma Aminobutyric Acid ◽  
Specific Procedure ◽  
Beta Alanine ◽  
Antihemophilic Factor

Summary1. The use of several amino acids, glycine, alpha-aminobutyric acid, alanine, beta-alanine, and gamma-aminobutyric acid, as plasma protein precipitants is described.2. A specific procedure is detailed for the preparation of canine antihemophilic factor (AHF, Factor VIII) in which glycine, beta-alanine, and gammaaminobutyric acid serve as the protein precipitants.3. Preliminary results are reported for the precipitation of bovine and human AHF with amino acids.

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