Renin inhibitors. Design of angiotensinogen transition-state analogs containing novel (2R,3R,4R,5S)-5-amino-3,4-dihydroxy-2-isopropyl-7-methyloctanoic acid

1987 ◽  
Vol 30 (6) ◽  
pp. 976-982 ◽  
Author(s):  
Suvit Thaisrivongs ◽  
Donald T. Pals ◽  
Lisa T. Kroll ◽  
Steve R. Turner ◽  
Fu Son Han
Keyword(s):  
Transition State ◽  
Renin Inhibitors ◽  
Transition State Analogs

On the rational design of renin inhibitors: x-ray studies of aspartic proteinases complexed with transition-state analogs

Biochemistry ◽  
1987 ◽  
Vol 26 (18) ◽  
pp. 5585-5590 ◽  
Author(s):  
T. L. Blundell ◽  
J. Cooper ◽  
S. I. Foundling ◽  
D. M. Jones ◽  
B. Atrash ◽  
...  
Keyword(s):  
Transition State ◽  
Rational Design ◽  
Aspartic Proteinases ◽  
X Ray ◽  
Renin Inhibitors ◽  
Transition State Analogs

Renin inhibitors. Synthesis of transition-state analog inhibitors containing phosphorus acid derivatives at the scissile bond

1989 ◽  
Vol 32 (7) ◽  
pp. 1652-1661 ◽  
Author(s):  
Mark C. Allen ◽  
Walter Fuhrer ◽  
Brian Tuck ◽  
Roy Wade ◽  
Jeanette M. Wood
Keyword(s):  
Transition State ◽  
Phosphorus Acid ◽  
Transition State Analog ◽  
Renin Inhibitors ◽  
Scissile Bond

scholarly journals Transition state analogs of 5′-methylthioadenosine nucleosidase disrupt quorum sensing

2009 ◽  
Vol 5 (4) ◽  
pp. 251-257 ◽  
Author(s):  
Jemy A Gutierrez ◽  
Tamara Crowder ◽  
Agnes Rinaldo-Matthis ◽  
Meng-Chiao Ho ◽  
Steven C Almo ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Transition State ◽  
Transition State Analogs
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