A new class of nitrosoureas. 4. Synthesis and antitumor activity of disaccharide derivatives of 3,3-disubstituted 1-(2-chloroethyl)-1-nitrosoureas

1982 ◽  
Vol 25 (4) ◽  
pp. 441-446 ◽  
Author(s):  
Kenji Tsujihara ◽  
Masakatsu Ozeki ◽  
Tamio Morikawa ◽  
Masatoshi Kawamori ◽  
Yukio Akaike ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
New Class ◽  
Derivatives Of

ChemInform Abstract: SYNTHESIS AND ANTITUMOR ACTIVITY OF 6-OXO-7-AMINO DERIVATIVES OF 5H-PYRIDO(2,3B)- AND 5H-PYRIMIDO(4,5B)(1,4)THIAZINES

1985 ◽  
Vol 16 (15) ◽  
Author(s):  
N. I. TRAVEN' ◽  
YU. A. ERSHOVA ◽  
A. S. SOKOLOVA ◽  
V. A. CHERNOV ◽  
T. S. SAFONOVA
Keyword(s):  
Antitumor Activity ◽  
Amino Derivatives ◽  
Derivatives Of

Synthesis, in vitro and in vivo antitumor activity of symmetrical bis-Schiff base derivatives of isatin

2014 ◽  
Vol 74 ◽  
pp. 742-750 ◽  
Author(s):  
Chengyuan Liang ◽  
Juan Xia ◽  
Dong Lei ◽  
Xiang Li ◽  
Qizheng Yao ◽  
...  
Keyword(s):  
Schiff Base ◽  
Antitumor Activity ◽  
Schiff Base Derivatives ◽  
In Vivo Antitumor Activity ◽  
Derivatives Of

scholarly journals Preparation and Antitumor Activity of 2''-O-,3''-O-and 2'',3''-Di-O-substituted Derivatives of Etoposide.

1992 ◽  
Vol 40 (7) ◽  
pp. 1783-1788 ◽  
Author(s):  
Takeshi OHNUMA ◽  
Rika OBATA ◽  
Yuji NISHIYAMA ◽  
Tetsuro YAMASAKI ◽  
Hideo KAMEI ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Derivatives Of

The Preparation and Antitumor Activity of Certain Derivatives of 6-Mercaptopurine

1962 ◽  
Vol 5 (3) ◽  
pp. 607-617 ◽  
Author(s):  
Leland R. Lewis ◽  
C. Wayne. Noell ◽  
Alden G. Beaman ◽  
Roland K. Robins
Keyword(s):  
Antitumor Activity ◽  
Derivatives Of

STUDY OF THE BIOLOGICAL PROPERTIES OF SEMI- AND THIOSEMICARBAZONES OF CARBONYL DERIVATIVES OF 4-BUTANOLIDES

2021 ◽  
Vol 55 (2 (255)) ◽  
pp. 103-111
Author(s):  
Tariel V. Ghochikyan ◽  
Armen S. Galstyan ◽  
Hrachik M. Stepanyan ◽  
Irina G. Korpakova ◽  
Alexander S. Kinzirsky
Keyword(s):  
Antitumor Activity ◽  
Green Alga ◽  
Biological Properties ◽  
Lymphocytic Leukemia ◽  
Thiazole Ring ◽  
Lewis Lung ◽  
Ehrlich's Ascites Tumor ◽  
Carbonyl Derivatives ◽  
Derivatives Of ◽  
Test Objects

Based on carbonyl derivatives of 4-substituted-4-butanolides, the appropriate semi- and thiosemicarbazones have been synthesized. It has been found that some representatives of thiosemicarbazones have pronounced algicidal activity against filamentous green alga Cladophora and blue-green alga (cyanobacterium) Synechocystis and some of the semi- and thiosemicarbazones exhibit moderate antitumor activity. The assessment of the antitumor activity of the compounds was carried out using strains of syngeneic and allogeneic tumor systems as test-objects: lymphocytic leukemia P-388, Lewis lung carcinoma, B16 melanoma and Ehrlich’s ascites tumor. It has also been established that some representatives of thiosemi­carbazones exhibit antimutagenic properties. It has been reliably proven that with the formation of a thiazole ring, all properties disappear and a new property in the series of thiazololactones is revealed – antibacterial․

Synthesis and antitumor activity of heterocyclic acid ester derivatives of 20S-camptothecins

2007 ◽  
Vol 18 (11) ◽  
pp. 1335-1338 ◽  
Author(s):  
Di Zao Li ◽  
Yan Li ◽  
Xiao Guang Chen ◽  
Chen Gen Zhu ◽  
Jing Yang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Acid Ester ◽  
Derivatives Of
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