The Synthesis of Two New Metabolites of Catecholamines: 3,4-Dihydroxyphenylethyleneglycol and 4-Hydroxy-3-methoxyphenylethyleneglycol1

1963 ◽  
Vol 6 (5) ◽  
pp. 607-608 ◽  
Author(s):  
J. D. Benigni ◽  
Anthony J. Verbiscar
Keyword(s):  
New Metabolites

scholarly journals THE CHARACTERIZATION OF FOUR NEW METABOLITES OF ADRENOCORTICAL HORMONES

1955 ◽  
Vol 212 (1) ◽  
pp. 449-460 ◽  
Author(s):  
David K. Fukushima ◽  
Norma S. Leeds ◽  
H. Leon Bradlow ◽  
Theodore H. Kritchevsky ◽  
Madeleine B. Stokem ◽  
...  
Keyword(s):  
Adrenocortical Hormones ◽  
New Metabolites

Lactarane Type Sesquiterpenoids as Inhibitors of Leukotriene Biosynthesis and Other, New Metabolites from Submerged Cultures of Lentinellus cochleatus (Pers. ex Fr.) Karst

1996 ◽  
Vol 51 (7-8) ◽  
pp. 493-499 ◽  
Author(s):  
Annette Wunder ◽  
Timm Anke ◽  
Dörte Klostermeyer ◽  
Wolfgang Steglich
Keyword(s):  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Peripheral Blood Leukocytes ◽  
Submerged Cultures ◽  
Blood Leukocytes ◽  
Spectroscopic Investigations ◽  
Basophilic Leukemia ◽  
New Metabolites

Abstract Three known sesquiterpenoids of the lactarane and secolactarane type, deoxylactarorufin A (1), blennin A (2) and blennin C (3), have been obtained from cultures of Lentinellus cochleatus (Basidiomycetes) together with the new metabolites (Z)-2-chloro-3-(4-me-thoxyphenyl)-2-propen-l-ol (4) and lentinellone (5), a protoilludane derivative. The structures were determined by spectroscopic investigations. 1, 2 and 3 are potent inhibitors of leukotriene biosynthesis in rat basophilic leukemia (RBL-1) cells and human peripheral blood leukocytes (PBL).

New metabolites of Azotobacter vinelandii exhibiting antifungal activity

Microbiology ◽  
2009 ◽  
Vol 78 (4) ◽  
pp. 428-432 ◽  
Author(s):  
S. P. Chetverikov ◽  
O. N. Loginov
Keyword(s):  
Antifungal Activity ◽  
Azotobacter Vinelandii ◽  
New Metabolites

scholarly journals O-Demethylpaulomycins A and B, U-77,802 and U-77,803, paulomenols A and B, new metabolites produced by Streptomyces paulus.

1988 ◽  
Vol 41 (10) ◽  
pp. 1316-1330 ◽  
Author(s):  
A. D. ARGOUDELIS ◽  
L. BACZYNSKYJ ◽  
S. A. MIZSAK ◽  
F. B. SHILLIDAY
Keyword(s):  
New Metabolites

Cytotoxic effects of three new metabolites from Red Sea marine sponge, Petrosia sp.

2014 ◽  
Vol 37 (3) ◽  
pp. 928-935 ◽  
Author(s):  
Ahmed Abdel-Lateff ◽  
Walied M. Alarif ◽  
Hany Z. Asfour ◽  
Seif-Eldin N. Ayyad ◽  
Alaa Khedr ◽  
...  
Keyword(s):  
Red Sea ◽  
Marine Sponge ◽  
Cytotoxic Effects ◽  
New Metabolites

New metabolites of thiabendazole and the metabolism of thiabendazole by mouse embryo in vivo and in vitro

1991 ◽  
Vol 29 (4) ◽  
pp. 265-274 ◽  
Author(s):  
T. Fujitani ◽  
M. Yoneyama ◽  
A. Ogata ◽  
T. Ueta ◽  
K. Mori ◽  
...  
Keyword(s):  
Mouse Embryo ◽  
New Metabolites

scholarly journals Trichilones A–E: New Limonoids from Trichilia adolfi

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3070
Author(s):  
Mariela Gonzalez-Ramirez ◽  
Ivan Limachi ◽  
Sophie Manner ◽  
Juan C. Ticona ◽  
Efrain Salamanca ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
High Field ◽  
Chemical Constituents ◽  
Ethanol Extract ◽  
Raw 264.7 Cells ◽  
Raw 264.7 ◽  
Murine Macrophage ◽  
New Metabolites

In addition to the trichilianones A–D recently reported from Trichilia adolfi, a continuing investigation of the chemical constituents of the ethanol extract of the bark of this medicinal plant yielded the five new limonoids 1–5. They are characterized by having four fused rings and are new examples of prieurianin-type limonoids, having a ε-lactone which in 4 and 5 is α, β- unsaturated. The structures of the isolated metabolites were determined by high field NMR spectroscopy and HR mass spectrometry. The new metabolites were shown to have the ε-lactone fused with a tetrahydrofuran ring which is connected to an oxidized hexane ring joined with a cyclo-pentanone having a 3-furanyl substituent. As the crude extract possesses antileishmanial activity, the compounds were assayed for cytotoxic and antiparasitic activities in vitro in murine macrophage cells (raw 264.7 cells) and in Leishmania amazoniensis as well as L. braziliensis promastigotes. Metabolites 1–3 and 5 showed moderate cytotoxicity (between 30–94 µg/mL) but are not responsible for the antileishmanial effect of the extract.

Sambucinol and sambucoin, two new metabolites ofFusarium sambucinumpossessing modified trichothecene structures. 41st Communication on verrucarins an roridins

1984 ◽  
Vol 67 (2) ◽  
pp. 406-412 ◽  
Author(s):  
Perer Mohr ◽  
Christoph Tamm ◽  
Werner Zürcher ◽  
Margareta Zehnder
Keyword(s):  
New Metabolites

scholarly journals Aranochlor A and Aranochlor B, Two New Metabolites from Pseudoarachniotus roseus: Production, Isolation, Structure Elucidation and Biological Properties.

1998 ◽  
Vol 51 (4) ◽  
pp. 439-441 ◽  
Author(s):  
TRIPTIKUMAR MUKHOPADHYAY ◽  
R. G. BHAT ◽  
KIRITY ROY ◽  
E. K. S. VIJAYAKUMAR ◽  
B. N. GANGULI
Keyword(s):  
Structure Elucidation ◽  
Biological Properties ◽  
New Metabolites

New metabolites of the drug 5-aminosalicylic acid. II. N-Formyl-5-aminosalicylic acid

Xenobiotica ◽  
1991 ◽  
Vol 21 (5) ◽  
pp. 605-612 ◽  
Author(s):  
J. Tjørnelund ◽  
S. H. Hansen ◽  
C. Cornett
Keyword(s):  
Aminosalicylic Acid ◽  
New Metabolites
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