Analogs of Steroid Hormones. I. 6-(4-Oxocyclohexenyl) and 6-(p-Hydroxyphenyl) Derivatives of 2-Naphthalenone1

1964 ◽  
Vol 7 (4) ◽  
pp. 519-524 ◽  
Author(s):  
R. E. Juday ◽  
D. P. Page ◽  
G. A. Du Vall
Keyword(s):  
Steroid Hormones ◽  
Derivatives Of

N′-(2-chloroethyl)-N′-nitrosocarbamoyl amino acid derivatives of steroid hormones

1987 ◽  
Vol 14 (3-4) ◽  
pp. 285-290 ◽  
Author(s):  
G. Eisenbrand ◽  
M. Berger ◽  
J. Fischer ◽  
M. Schneider ◽  
W. Zeller ◽  
...  
Keyword(s):  
Amino Acid ◽  
Steroid Hormones ◽  
Amino Acid Derivatives ◽  
Derivatives Of

Steroid hormones. XXI. Some testosterone derivatives substituted at C19

1970 ◽  
Vol 23 (2) ◽  
pp. 341 ◽  
Author(s):  
AJ Birch ◽  
B McKague
Keyword(s):  
Steroid Hormones ◽  
Methyl Ether ◽  
Isoprene Unit ◽  
Alcohol Mixture ◽  
Methylmagnesium Iodide ◽  
Ring Fission ◽  
Similar Series ◽  
Derivatives Of

Addition of but-1-en-3-one to (1) produced the adducts (28) and (2b) which undergo ring fission with acid to give (3). Methylmagnesium iodide on (2a) and (2b) gives the alcohol mixture (4) which is converted by acid into (5). A similar series of reactions with derivatives of l,2-dihydrooestrone methyl ether gives the steroid (10) and the 17β-OH analogue, and (11) containing an angular isoprene unit.

Analogs of steroid hormones. II. 6-(Cyclopentyl) derivatives of 2-naphthalenone

1968 ◽  
Vol 11 (4) ◽  
pp. 872-875
Author(s):  
R. E. Juday ◽  
Lynette Cubbage ◽  
Judith Mazur ◽  
Bonnie Bukwa
Keyword(s):  
Steroid Hormones ◽  
Derivatives Of

Some Tetrahydropyranyl Ether Derivatives of Steroid Hormones

1961 ◽  
Vol 50 (1) ◽  
pp. 86-87 ◽  
Author(s):  
Lewis J. Leeson ◽  
Joseph F. Weidenheimer
Keyword(s):  
Steroid Hormones ◽  
Tetrahydropyranyl Ether ◽  
Derivatives Of

scholarly journals Possibility of using fullerene C240 as the carrier of steroid hormones

2016 ◽  
Author(s):  
Monika K Grudzień ◽  
Izabela Wiśniewska ◽  
Marcin Suskiewicz ◽  
Tomasz Pieńko ◽  
Aleksander P. Mazurek
Keyword(s):  
Molecular Modeling ◽  
Carbon Atom ◽  
Steroid Hormones ◽  
Modeling Technique ◽  
Carbon Cage ◽  
Endohedral Fullerenes ◽  
Endohedral Complex ◽  
The Family ◽  
Formation Heat ◽  
Derivatives Of

Fullerene molecules are created entirely of carbon and form orbicular or ellipsoidal cage shape similar to a hollow tube. The derivatives of fullerenes are classified into the following categories according to their functionalization: endohedral fullerenes with active molecules residing inside the carbon cage, exohedral with wide variety of both inorganic and organic groups existing outside and connected to the fullerenes’ exterior and heterofullerenes when one or more carbon atoms that form the fullerene carbon cage are replaced by a non-carbon atom, i.e. a heteroatom. Fullerene C240belongs to the family of giant fullerenes and is characterized by a greater stability than that of the well-known fullerene C60. This has been proved by observing an increased formation heat that accompanied the decreasing of the carbon cage size.In order to determine the fullerene C240 ability to transport the steroid hormones: estradiol, progesterone, androsterone and their basic structures: estrone, androstane and pregnane, the following parameters, inter alia, have been calculated: energies of stabilization, interaction and deformation of each endohedral complex. The calculations for all chosen structures were carried out with the use of the molecular modeling technique. Based on all available studies, it can be stated that fullerene C240 could be a solution for problems faced by medicine and pharmacy.

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