Analogs of luteinizing hormone-releasing hormone with increased biological activity produced by D-amino acid substitutions in position 6

David H. Coy; Jesus A. Vilchez-Martinez; Esther J. Coy; Andrew V. Schally

doi:10.1021/jm00225a018

Analogs of luteinizing hormone-releasing hormone with increased biological activity produced by D-amino acid substitutions in position 6

Journal of Medicinal Chemistry ◽

10.1021/jm00225a018 ◽

1976 ◽

Vol 19 (3) ◽

pp. 423-425 ◽

Cited By ~ 107

Author(s):

David H. Coy ◽

Jesus A. Vilchez-Martinez ◽

Esther J. Coy ◽

Andrew V. Schally

Keyword(s):

Biological Activity ◽

Amino Acid ◽

Luteinizing Hormone ◽

Amino Acid Substitutions ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone

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ChemInform Abstract: ANALOGS OF LUTEINIZING HORMONE-RELEASING HORMONE WITH INCREASED BIOLOGICAL ACTIVITY PRODUCED BY D-AMINO ACID SUBSTITUTIONS IN POSITION 6

Chemischer Informationsdienst ◽

10.1002/chin.197627362 ◽

1976 ◽

Vol 7 (27) ◽

pp. no-no

Author(s):

D. H. COY ◽

J. A. VILCHEZ-MARTINEZ ◽

E. J. COY ◽

A. V. SCHALLY

Keyword(s):

Biological Activity ◽

Amino Acid ◽

Luteinizing Hormone ◽

Amino Acid Substitutions ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone

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ChemInform Abstract: EFFECT OF SIMPLE AMINO ACID REPLACEMENTS ON THE BIOLOGICAL ACTIVITY OF LUTEINIZING HORMONE-RELEASING HORMONE

Chemischer Informationsdienst ◽

10.1002/chin.197404388 ◽

1974 ◽

Vol 5 (4) ◽

pp. no-no

Author(s):

D. H. COY ◽

E. J. COY ◽

A. V. SCHALLY

Keyword(s):

Biological Activity ◽

Amino Acid ◽

Luteinizing Hormone ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone ◽

Simple Amino Acid

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Effect of simple amino acid replacements on the biological activity of luteinizing hormone-releasing hormone

Journal of Medicinal Chemistry ◽

10.1021/jm00268a016 ◽

1973 ◽

Vol 16 (10) ◽

pp. 1140-1143 ◽

Cited By ~ 29

Author(s):

David H. Coy ◽

Esther J. Coy ◽

Andrew V. Schally

Keyword(s):

Biological Activity ◽

Amino Acid ◽

Luteinizing Hormone ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone ◽

Simple Amino Acid

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ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF PEPTIDE ANTAGONISTS OF LULIBERIN (LUTEINIZING HORMONE-RELEASING HORMONE)

Chemischer Informationsdienst ◽

10.1002/chin.198016313 ◽

1980 ◽

Vol 11 (16) ◽

Author(s):

G. W. MOERSCH ◽

M. C. REBSTOCK ◽

E. L. WITTLE ◽

F. J. TINNEY ◽

E. D. NICOLAIDES ◽

...

Keyword(s):

Biological Activity ◽

Luteinizing Hormone ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone

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Biological activity of luteinizing hormone in uraemic children: spontaneous nocturnal secretion and changes after administration of exogenous pulsatile luteinizing hormone-releasing hormone ? preliminary observations

Pediatric Nephrology ◽

10.1007/bf01453702 ◽

1991 ◽

Vol 5 (4) ◽

pp. 559-565 ◽

Cited By ~ 10

Author(s):

Massimo Giusti ◽

Francesco Perfumo ◽

Enrico Verrina ◽

Domenico Cavallero ◽

Giorgio Piaggio ◽

...

Keyword(s):

Biological Activity ◽

Luteinizing Hormone ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone ◽

Uraemic Children

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ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF LUTEINIZING HORMONE-RELEASING HORMONE AND RELATED PEPTIDES

Chemischer Informationsdienst ◽

10.1002/chin.197540392 ◽

1975 ◽

Vol 6 (40) ◽

pp. no-no

Author(s):

D. J. SCHAFER ◽

A. D. BLACK ◽

J. D. BOWER ◽

D. B. CRIGHTON

Keyword(s):

Biological Activity ◽

Luteinizing Hormone ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone

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ChemInform Abstract: ANALOGS OF THE LUTEINIZING HORMONE-RELEASING HORMONE TO STUDY CONFORMATIONAL ASPECTS OF THE AMINO ACID MOIETIES AND INHIBITION

Chemischer Informationsdienst ◽

10.1002/chin.197441446 ◽

1974 ◽

Vol 5 (41) ◽

Author(s):

J. HUMPHRIES ◽

G. FISHER ◽

Y. P. WAN ◽

K. FOLKERS ◽

C. Y. BOWERS

Keyword(s):

Amino Acid ◽

Luteinizing Hormone ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone

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Luteinizing hormone releasing hormone. Solid-phase synthesis of a 5-phenylalanine analog possessing high biological activity

Journal of Medicinal Chemistry ◽

10.1021/jm00259a023 ◽

1973 ◽

Vol 16 (1) ◽

pp. 83-84 ◽

Cited By ~ 23

Author(s):

David H. Coy ◽

Esther J. Coy ◽

Andrew V. Schally

Keyword(s):

Biological Activity ◽

Luteinizing Hormone ◽

Solid Phase Synthesis ◽

Solid Phase ◽

High Biological Activity ◽

Phase Synthesis ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone

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A luteinizing hormone-releasing hormone agonist decreases biological activity and modifies chromatographic behavior of luteinizing hormone in man.

Journal of Clinical Investigation ◽

10.1172/jci111200 ◽

1984 ◽

Vol 73 (1) ◽

pp. 262-266 ◽

Cited By ~ 68

Author(s):

R M Evans ◽

G C Doelle ◽

J Lindner ◽

V Bradley ◽

D Rabin

Keyword(s):

Biological Activity ◽

Luteinizing Hormone ◽

Chromatographic Behavior ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone

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Synthesis and biological activity of luteinizing hormone-releasing hormone and related peptides

Journal of Medicinal Chemistry ◽

10.1021/jm00240a018 ◽

1975 ◽

Vol 18 (6) ◽

pp. 613-619 ◽

Cited By ~ 4

Author(s):

Derek J. Schafer ◽

Alan D. Black ◽

John D. Bower ◽

D. Barry Crighton

Keyword(s):

Biological Activity ◽

Luteinizing Hormone ◽

Luteinizing Hormone Releasing Hormone ◽

Releasing Hormone

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