Analgesic activity of novel spiro heterocycles. 2-Amino-7-oxa-3-thia-1-azaspiro[5.5]undec-1-enes and related compounds

1978 ◽  
Vol 21 (9) ◽  
pp. 895-900 ◽  
Author(s):  
Noal Cohen ◽  
Bruce L. Banner ◽  
Rocco J. Lopresti ◽  
Herman W. Baruth
1985 ◽  
Vol 28 (8) ◽  
pp. 1037-1049 ◽  
Author(s):  
Joseph M. Muchowski ◽  
Stefan H. Unger ◽  
Jack Ackrell ◽  
Paul Cheung ◽  
James Cook ◽  
...  

1971 ◽  
Vol 49 (3) ◽  
pp. 485-492 ◽  
Author(s):  
D. E. Horning ◽  
J. M. Muchowski

The synthesis and spectral properties of some two- and three-carbon ortho-bridged analogues of the analgesic methadone are described. These compounds were devoid of analgesic activity.


1984 ◽  
Vol 32 (6) ◽  
pp. 2279-2289 ◽  
Author(s):  
TAKESHI KATO ◽  
HARUMITSU ISHII ◽  
KIYOHISA KAWAI ◽  
YOICHI SAWA

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