Potential antitumor agents. 45. Synthesis, DNA-binding interaction, and biological activity of triacridine derivatives

Graham J. Atwell; Bruce C. Baguley; Dorota Wilmanska; William A. Denny

doi:10.1021/jm00151a011

Potential antitumor agents. 45. Synthesis, DNA-binding interaction, and biological activity of triacridine derivatives

Journal of Medicinal Chemistry ◽

10.1021/jm00151a011 ◽

1986 ◽

Vol 29 (1) ◽

pp. 69-74 ◽

Cited By ~ 20

Author(s):

Graham J. Atwell ◽

Bruce C. Baguley ◽

Dorota Wilmanska ◽

William A. Denny

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Agents ◽

Binding Interaction ◽

Potential Antitumor

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ChemInform Abstract: Potential Antitumor Agents. Part 44. Synthesis and Antitumor Activity of New Classes of Diacridines: Importance of Linker Chain Rigidity for DNA Binding Kinetics and Biological Activity.

Chemischer Informationsdienst ◽

10.1002/chin.198609180 ◽

1986 ◽

Vol 17 (9) ◽

Author(s):

W. A. DENNY ◽

G. J. ATWELL ◽

B. C. BAGULEY ◽

L. P. G. WAKELIN

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Activity ◽

Antitumor Agents ◽

Binding Kinetics ◽

Chain Rigidity ◽

Linker Chain ◽

Potential Antitumor

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Potential antitumor agents. 44. Synthesis and antitumor activity of new classes of diacridines: importance of linker chain rigidity for DNA binding kinetics and biological activity

Journal of Medicinal Chemistry ◽

10.1021/jm00149a005 ◽

1985 ◽

Vol 28 (11) ◽

pp. 1568-1574 ◽

Cited By ~ 75

Author(s):

William A. Denny ◽

Graham J. Atwell ◽

Bruce C. Baguley ◽

Laurence P. G. Wakelin

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Activity ◽

Antitumor Agents ◽

Binding Kinetics ◽

Chain Rigidity ◽

Linker Chain ◽

Potential Antitumor

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ChemInform Abstract: Potential Antitumor Agents. Part 53. Synthesis, DNA Binding Properties, and Biological Activity of Perimidines Designed as “Minimal” DNA-Intercalating Agents.

ChemInform ◽

10.1002/chin.198815233 ◽

1988 ◽

Vol 19 (15) ◽

Author(s):

J. M. HERBERT ◽

P. D. WOODGATE ◽

W. A. DENNY

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Agents ◽

Binding Properties ◽

Intercalating Agents ◽

Dna Binding Properties ◽

Potential Antitumor

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Potential antitumor agents. 53. Synthesis, DNA binding properties, and biological activity of perimidines designed as minimal DNA-intercalating agents

Journal of Medicinal Chemistry ◽

10.1021/jm00394a025 ◽

1987 ◽

Vol 30 (11) ◽

pp. 2081-2086 ◽

Cited By ~ 63

Author(s):

John M. Herbert ◽

Paul D. Woodgate ◽

William A. Denny

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Agents ◽

Binding Properties ◽

Intercalating Agents ◽

Dna Binding Properties ◽

Potential Antitumor

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ChemInform Abstract: Potential Antitumor Agents. Synthesis, DNA Binding Studies, and Biological Activity of 9-Aminoacridinyl Derivatives of Citrulline and Arginine.

ChemInform ◽

10.1002/chin.199101221 ◽

2010 ◽

Vol 22 (1) ◽

pp. no-no ◽

Cited By ~ 1

Author(s):

M. RAD-NIKNAM ◽

D. SHARPLES

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Agents ◽

Binding Studies ◽

Dna Binding Studies ◽

Derivatives Of ◽

Potential Antitumor

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ChemInform Abstract: POTENTIAL ANTITUMOR AGENTS. PART 43. SYNTHESIS AND BIOLOGICAL ACTIVITY OF DIBASIC 9-AMINOACRIDINE-4-CARBOXAMIDES, A NEW CLASS OF ANTITUMOR AGENT

Chemischer Informationsdienst ◽

10.1002/chin.198512225 ◽

1985 ◽

Vol 16 (12) ◽

Author(s):

G. J. ATWELL ◽

B. F. CAIN ◽

B. C. BAGULEY ◽

G. J. FINLAY ◽

W. A. DENNY

Keyword(s):

Biological Activity ◽

Antitumor Agents ◽

Antitumor Agent ◽

New Class ◽

Potential Antitumor

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ChemInform Abstract: Potential Antitumor Agents. Part 45. Synthesis, DNA-Bindung Interaction and Biological Activity of Triacridine Derivatives.

Chemischer Informationsdienst ◽

10.1002/chin.198620209 ◽

1986 ◽

Vol 17 (20) ◽

Author(s):

G. J. ATWELL ◽

B. C. BAGULEY ◽

D. WILMANSKA ◽

W. A. DENNY

Keyword(s):

Biological Activity ◽

Antitumor Agents ◽

Potential Antitumor

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Synthesis, characterization and DNA-binding properties of Ru(II) complexes coordinated by ofloxacin as potential antitumor agents

Journal of Coordination Chemistry ◽

10.1080/00958972.2015.1020797 ◽

2015 ◽

Vol 68 (9) ◽

pp. 1489-1499 ◽

Cited By ~ 10

Author(s):

Chengxi Wang ◽

Qiong Wu ◽

Yongchang Zeng ◽

Dongwei Huang ◽

Chuqin Yu ◽

...

Keyword(s):

Dna Binding ◽

Antitumor Agents ◽

Binding Properties ◽

Dna Binding Properties ◽

Potential Antitumor

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Structure–activity relationships in glycosylated 2-phenyl-indoles, 2-phenyl-benzo[b]thiophenes and 2-phenyl-benzo[b]furans as DNA binding and potential antitumor agents

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2011.01.014 ◽

2011 ◽

Vol 19 (5) ◽

pp. 1779-1789 ◽

Cited By ~ 10

Author(s):

Wei Shi ◽

Todd L. Lowary

Keyword(s):

Dna Binding ◽

Antitumor Agents ◽

Structure Activity Relationships ◽

Structure Activity ◽

Potential Antitumor

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Discovery of a novel DNA binding agent via design and synthesis of new thiazole hybrids and fused 1,2,4-triazines as potential antitumor agents: Computational, spectrometric and in silico studies

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103089 ◽

2019 ◽

Vol 90 ◽

pp. 103089 ◽

Cited By ~ 4

Author(s):

Marwa H. El-Wakil ◽

Amira F. El-Yazbi ◽

Hayam M.A. Ashour ◽

Mounir A. Khalil ◽

Khadiga A. Ismail ◽

...

Keyword(s):

Dna Binding ◽

In Silico ◽

Antitumor Agents ◽

Binding Agent ◽

Design And Synthesis ◽

In Silico Studies ◽

Potential Antitumor

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