Synthesis and antiviral activity of certain guanosine analogs in the thiazolo[4,5-d]pyrimidine ring system

1991 ◽  
Vol 34 (10) ◽  
pp. 3006-3010 ◽  
Author(s):  
Ganesh D. Kini ◽  
Jack D. Anderson ◽  
Yogesh S. Sanghvi ◽  
Arthur F. Lewis ◽  
Donald F. Smee ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Pyrimidine Ring ◽  
Ring System

ChemInform Abstract: Synthesis and Antiviral Activity of Certain Guanosine Analogues in the Thiazolo(4,5-d)pyrimidine Ring System.

ChemInform ◽  
2010 ◽  
Vol 23 (15) ◽  
pp. no-no
Author(s):  
G. D. KINI ◽  
J. D. ANDERSON ◽  
Y. S. SANGHVI ◽  
A. F. LEWIS ◽  
D. F. SMEE ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Pyrimidine Ring ◽  
Ring System

An Intramolecular Sulfoxide Alkylation-Elimination Approach to the [1,2,3]Triazolo[1,5-a]pyrimidine Ring System

Synlett ◽  
2001 ◽  
Vol 2001 (05) ◽  
pp. 0712-0714 ◽  
Author(s):  
Karl R. Gibson ◽  
Steven R. Thomas ◽  
Michael Rowley
Keyword(s):  
Pyrimidine Ring ◽  
Ring System

scholarly journals Crystal structure of 1-methyl-4-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidine

2014 ◽  
Vol 70 (12) ◽  
pp. o1281-o1281 ◽  
Author(s):  
Mohammed El Fal ◽  
Youssef Ramli ◽  
El Mokhtar Essassi ◽  
Mohamed Saadi ◽  
Lahcen El Ammari
Keyword(s):  
Crystal Structure ◽  
Title Compound ◽  
Three Dimensional ◽  
Pyrimidine Ring ◽  
Ring System ◽  
Dimensional Structure ◽  
Mirror Plane ◽  
Three Dimensional Structure ◽  
Π Interactions ◽  
Compound C

In the title compound, C7H8N4S, the non-H atoms of the pyrazolo[3,4-d]pyrimidine ring system and the methylsulfanyl group lie on a crystallographic mirror plane. In the crystal, molecules are linkedviaa number of π–π interactions [centroid–centroid distances vary from 3.452 (7) to 3.6062 (8) Å], forming a three-dimensional structure.

scholarly journals Crystal structure of 4-allylsulfanyl-1H-pyrazolo[3,4-d]pyrimidine

2014 ◽  
Vol 70 (9) ◽  
pp. o1038-o1038 ◽  
Author(s):  
Mohammed El Fal ◽  
Youssef Ramli ◽  
El Mokhtar Essassi ◽  
Mohamed Saadi ◽  
Lahcen El Ammari
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonds ◽  
Title Compound ◽  
Pyrimidine Ring ◽  
Ring System ◽  
Maximum Deviation ◽  
Compound C ◽  
The Mean ◽  
Graph Set

In the title compound, C8H8N4S, the pyrazolo[3,4-d]pyrimidine ring system is essentially planar, with a maximum deviation from the mean plane of 0.025 (3) Å. The allyl group is disordered over two sites in a 0.512 (6):0.488 (6) ratio. In the crystal, molecules are linked by pairs of N—H...N hydrogen bonds, forming inversion dimers with anR22(8) graph-set motif.

Guanosine analog in the pyrido[2,3-d]pyrimidine ring system As a potential Toll-like receptor agonist

2006 ◽  
Vol 25 (12) ◽  
pp. 1391-1397 ◽  
Author(s):  
Guangyi Jin ◽  
Christina C. N. Wu ◽  
Dennis A. Carson ◽  
Howard B. Cottam
Keyword(s):  
Receptor Agonist ◽  
Pyrimidine Ring ◽  
Ring System ◽  
Toll Like Receptor

scholarly journals Crystal structure of cyprodinil

2015 ◽  
Vol 71 (1) ◽  
pp. o5-o5 ◽  
Author(s):  
Youngeun Jeon ◽  
Gihaeng Kang ◽  
Seonghwa Cho ◽  
Tae Ho Kim
Keyword(s):  
Crystal Structure ◽  
Title Compound ◽  
Phenyl Ring ◽  
Cyclopropane Ring ◽  
Pyrimidine Ring ◽  
Ring System ◽  
Dihedral Angles ◽  
Π Interactions ◽  
Compound C ◽  
The Mean

In the title compound, C14H15N3(systematic name: 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine), which is the anilinopyrimidine fungicide cyprodinil, the dihedral angles between the planes of the central pyrimidine ring and the terminal phenyl ring and the mean plane of the cyclopropane ring system are 14.52 (11) and 88.79 (10)°, respectively. In the crystal, weak π–π interactions [3.8551 (11) Å] connect the dimers into chains along theb-axis direction.

scholarly journals Crystal structure of ethyl 2-phenyl-4-(prop-2-yn-1-yloxy)-5,6,7,8-tetrahydropyrido[4′,3′:4,5]thieno[2,3-d]pyrimidine-7-carboxylate

2015 ◽  
Vol 71 (11) ◽  
pp. o836-o837
Author(s):  
Mehmet Akkurt ◽  
Victoria A. Smolenski ◽  
Shaaban K. Mohamed ◽  
Jerry P. Jasinski ◽  
Essam K Ahmed ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonds ◽  
Phenyl Ring ◽  
Crystal Packing ◽  
Three Dimensional ◽  
Chair Conformation ◽  
Pyrimidine Ring ◽  
Ring System ◽  
Compound C ◽  
Dimensional Crystal

In the title compound, C21H19N3O3S, the 5,6,7,8-tetrahydropyridine ring adopts a half-chair conformation. The fused-thieno[2,3-d]pyrimidine ring system is essentially planar (r.m.s. deviation = 0.001 Å) and forms a dihedral angle of 2.66 (6)° with the attached phenyl ring. The three-dimensional crystal packing is stabilized by C—H...O and C—H...N hydrogen bonds and C—H...π interactions.

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