Stereospecific synthesis of (R)- and (S)-S-adenosyl-1,8-diamino-3-thiooctane, a potent inhibitor of polyamine biosynthesis. Comparison of asymmetric induction vs enantiomeric synthesis

Chin Liu; James K. Coward

doi:10.1021/jm00111a026

Stereospecific synthesis of (R)- and (S)-S-adenosyl-1,8-diamino-3-thiooctane, a potent inhibitor of polyamine biosynthesis. Comparison of asymmetric induction vs enantiomeric synthesis

Journal of Medicinal Chemistry ◽

10.1021/jm00111a026 ◽

1991 ◽

Vol 34 (7) ◽

pp. 2094-2101 ◽

Cited By ~ 4

Author(s):

Chin Liu ◽

James K. Coward

Keyword(s):

Potent Inhibitor ◽

Asymmetric Induction ◽

Stereospecific Synthesis ◽

Polyamine Biosynthesis

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Stereospecific synthesis of (R)- and (S)-S-adenosyl-1,8-diamino-3-thiooctane, a potent inhibitor of polyamine biosynthesis. Comparison of asymmetric induction vs enantiomeric synthesis [Erratum to document cited in CA115(5):50181y]

Journal of Medicinal Chemistry ◽

10.1021/jm00116a014 ◽

1991 ◽

Vol 34 (12) ◽

pp. 3406-3408

Author(s):

Chin Liu ◽

James K. Coward

Keyword(s):

Potent Inhibitor ◽

Asymmetric Induction ◽

Stereospecific Synthesis ◽

Polyamine Biosynthesis

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ChemInform Abstract: ASYMMETRIC INDUCTION IN THE REDUCTION OF CHIRAL IMINES, STEREOSPECIFIC SYNTHESIS OF 20ALPHA-AMINO-5ALPHA-PREGNAN 3BETA-OL (FUNTUPHYLLAMINE A)

Chemischer Informationsdienst ◽

10.1002/chin.197541388 ◽

1975 ◽

Vol 6 (41) ◽

pp. no-no

Author(s):

G. DEMAILLY ◽

G. SOLLADIE

Keyword(s):

Asymmetric Induction ◽

Stereospecific Synthesis ◽

Chiral Imines

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Asymmetric induction in the reduction of chiral imines. Stereospecific synthesis of 20α-amino 5α-pregnan 3β-ol(Funtuphyllamine A).

Tetrahedron Letters ◽

10.1016/0040-4039(75)80040-2 ◽

1975 ◽

Vol 16 (29) ◽

pp. 2471-2472 ◽

Cited By ~ 7

Author(s):

Gilles Demailly ◽

Guy Solladie

Keyword(s):

Asymmetric Induction ◽

Stereospecific Synthesis ◽

Chiral Imines

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1-Aminooxy-3-aminopropane, a new and potent inhibitor of polyamine biosynthesis that inhibits ornithine decarboxylase, adenosylmethionine decarboxylase and spermidine synthase

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(85)90458-9 ◽

1985 ◽

Vol 130 (2) ◽

pp. 596-602 ◽

Cited By ~ 34

Author(s):

R.M. Khomutov ◽

T. Hyvönen ◽

E. Karvonen ◽

L. Kauppinen ◽

T. Paalanen ◽

...

Keyword(s):

Ornithine Decarboxylase ◽

Potent Inhibitor ◽

Spermidine Synthase ◽

Polyamine Biosynthesis ◽

Adenosylmethionine Decarboxylase

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Stereospecific synthesis of the C30-C43 segment of palytoxin by macrocyclically controlled remote asymmetric induction

Journal of the American Chemical Society ◽

10.1021/ja00370a071 ◽

1982 ◽

Vol 104 (6) ◽

pp. 1774-1776 ◽

Cited By ~ 46

Author(s):

W. Clark Still ◽

Igor Galynker

Keyword(s):

Asymmetric Induction ◽

Stereospecific Synthesis

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ChemInform Abstract: A Stereospecific Synthesis of 2′,3′-Dideoxy-β-L-cytidine (β- L-ddC), a Potent Inhibitor Against Human Hepatitis B Virus (HBV) and Human Immunodeficiency Virus (HIV).

ChemInform ◽

10.1002/chin.199442255 ◽

2010 ◽

Vol 25 (42) ◽

pp. no-no

Author(s):

T.-S. LIN ◽

M.-Z. LUO ◽

M.-C. LIU

Keyword(s):

Human Immunodeficiency Virus ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Potent Inhibitor ◽

Stereospecific Synthesis ◽

Human Hepatitis ◽

B Virus ◽

Immunodeficiency Virus

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ChemInform Abstract: STEREOSPECIFIC SYNTHESIS OF THE C30-C43 SEGMENT OF PALYTOXIN BY MACROCYCLICALLY CONTROLLED REMOTE ASYMMETRIC INDUCTION

Chemischer Informationsdienst ◽

10.1002/chin.198227338 ◽

1982 ◽

Vol 13 (27) ◽

Author(s):

W. C. STILL ◽

I. GALYNKER

Keyword(s):

Asymmetric Induction ◽

Stereospecific Synthesis

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A stereospecific synthesis of 2′,3′-dideoxy-β-l-cytidine (β-l-ddC), a potent inhibitor against human hepatitis B virus (HBV) and human immunodeficiency virus (HIV)

Tetrahedron Letters ◽

10.1016/s0040-4039(00)73214-x ◽

1994 ◽

Vol 35 (21) ◽

pp. 3477-3480 ◽

Cited By ~ 15

Author(s):

Tai-Shun Lin ◽

Mei-Zhen Luo ◽

Mao-Chin Liu

Keyword(s):

Human Immunodeficiency Virus ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Potent Inhibitor ◽

Stereospecific Synthesis ◽

Human Hepatitis ◽

B Virus ◽

Immunodeficiency Virus

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790: BMP-7 is a Potent Inhibitor of Prostate Cancer Bone Metastasis in Vivo

The Journal of Urology ◽

10.1016/s0022-5347(18)33026-x ◽

2006 ◽

Vol 175 (4S) ◽

pp. 255-256

Author(s):

Cyrill A. Rentsch ◽

Jeroen Buijs ◽

Geertje Van der Horst ◽

Petra Van Overveld ◽

Antoinette Wetterwald ◽

...

Keyword(s):

Prostate Cancer ◽

Bone Metastasis ◽

Potent Inhibitor

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Identification of plumericin from Himatanthus Sucuuba as a novel potent inhibitor of the NF-κB pathway directly targeting IKK-β

Planta Medica ◽

10.1055/s-0032-1320248 ◽

2012 ◽

Vol 78 (11) ◽

Author(s):

B Waltenberger ◽

N Fakhrudin ◽

M Cabaravdic ◽

AG Atanasov ◽

EH Heiss ◽

...

Keyword(s):

Potent Inhibitor

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