Structure/activity and molecular modeling studies of the lophotoxin family of irreversible nicotinic receptor antagonists

Stewart N. Abramson; Jacqueline A. Trischman; Dianne M. Tapiolas; Edward E. Harold; William Fenical; Palmer Taylor

doi:10.1021/jm00110a007

Structure/activity and molecular modeling studies of the lophotoxin family of irreversible nicotinic receptor antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm00110a007 ◽

1991 ◽

Vol 34 (6) ◽

pp. 1798-1804 ◽

Cited By ~ 50

Author(s):

Stewart N. Abramson ◽

Jacqueline A. Trischman ◽

Dianne M. Tapiolas ◽

Edward E. Harold ◽

William Fenical ◽

...

Keyword(s):

Molecular Modeling ◽

Nicotinic Receptor ◽

Receptor Antagonists ◽

Structure Activity ◽

Modeling Studies ◽

Molecular Modeling Studies

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ChemInform Abstract: Indole Amide Derivatives: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies of a New Series of Histamine H1-Receptor Antagonists.

ChemInform ◽

10.1002/chin.199929124 ◽

2010 ◽

Vol 30 (29) ◽

pp. no-no

Author(s):

Sandra Battaglia ◽

Enrico Boldrini ◽

Federico Da Settimo ◽

Giulio Dondio ◽

Concettina La Motta ◽

...

Keyword(s):

Molecular Modeling ◽

H1 Receptor ◽

Receptor Antagonists ◽

Histamine H1 Receptor ◽

Structure Activity Relationships ◽

Structure Activity ◽

Modeling Studies ◽

Amide Derivatives ◽

Molecular Modeling Studies

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Pyrazolo[1,5-c]quinazoline derivatives and their simplified analogues as adenosine receptor antagonists: Synthesis, structure–affinity relationships and molecular modeling studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2012.10.031 ◽

2013 ◽

Vol 21 (1) ◽

pp. 283-294 ◽

Cited By ~ 32

Author(s):

Daniela Catarzi ◽

Vittoria Colotta ◽

Flavia Varano ◽

Daniela Poli ◽

Lucia Squarcialupi ◽

...

Keyword(s):

Molecular Modeling ◽

Adenosine Receptor ◽

Receptor Antagonists ◽

Modeling Studies ◽

Molecular Modeling Studies ◽

Quinazoline Derivatives

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Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure–Activity Relationships, and Molecular Modeling Studies

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.6b00182 ◽

2016 ◽

Vol 7 (10) ◽

pp. 1418-1432 ◽

Cited By ~ 9

Author(s):

Chunyang Jin ◽

Ann M. Decker ◽

Danni L. Harris ◽

Bruce E. Blough

Keyword(s):

Molecular Modeling ◽

Structure Activity Relationships ◽

Structure Activity ◽

Modeling Studies ◽

Molecular Modeling Studies

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Structure–activity relationships of β-hydroxyphosphonate nucleoside analogues as cytosolic 5′-nucleotidase II potential inhibitors: Synthesis, in vitro evaluation and molecular modeling studies

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.02.055 ◽

2014 ◽

Vol 77 ◽

pp. 18-37 ◽

Cited By ~ 16

Author(s):

Maïa Meurillon ◽

Zsuzsanna Marton ◽

Audrey Hospital ◽

Lars Petter Jordheim ◽

Jérôme Béjaud ◽

...

Keyword(s):

Molecular Modeling ◽

Nucleoside Analogues ◽

In Vitro Evaluation ◽

Structure Activity Relationships ◽

Structure Activity ◽

Modeling Studies ◽

Molecular Modeling Studies ◽

Potential Inhibitors

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ChemInform Abstract: Novel Ligands Specific for Mitochondrial Benzodiazepine Receptors: 6- Arylpyrrolo(2,1-d) (1,5)benzothiazepine Derivatives. Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies.

ChemInform ◽

10.1002/chin.199439210 ◽

2010 ◽

Vol 25 (39) ◽

pp. no-no

Author(s):

I. FIORINI ◽

V. NACCI ◽

S. M. CIANI ◽

A. GAROFALO ◽

G. CAMPIANI ◽

...

Keyword(s):

Molecular Modeling ◽

Benzodiazepine Receptors ◽

Structure Activity Relationships ◽

Structure Activity ◽

Modeling Studies ◽

Molecular Modeling Studies

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1,2,4-Triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A3 receptor antagonists. Synthesis, structure–affinity relationships and molecular modeling studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.11.033 ◽

2015 ◽

Vol 23 (1) ◽

pp. 9-21 ◽

Cited By ~ 13

Author(s):

Daniela Catarzi ◽

Flavia Varano ◽

Daniela Poli ◽

Lucia Squarcialupi ◽

Marco Betti ◽

...

Keyword(s):

Molecular Modeling ◽

Receptor Antagonists ◽

Adenosine A3 Receptor ◽

Modeling Studies ◽

Quinoxaline Derivatives ◽

Molecular Modeling Studies

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Biological Evaluation, Chelation, and Molecular Modeling Studies of Novel Metal-Chelating Inhibitors of NF-κB-DNA Binding: Structure Activity Relationships

Journal of Medicinal Chemistry ◽

10.1021/jm050617x ◽

2006 ◽

Vol 49 (12) ◽

pp. 3595-3601 ◽

Cited By ~ 12

Author(s):

Rakesh K. Sharma ◽

Shilpa Chopra ◽

Som D. Sharma ◽

Vineet Pande ◽

Maria J. Ramos ◽

...

Keyword(s):

Molecular Modeling ◽

Dna Binding ◽

Biological Evaluation ◽

Structure Activity Relationships ◽

Metal Chelating ◽

Structure Activity ◽

Modeling Studies ◽

Molecular Modeling Studies ◽

Binding Structure

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Benzofurans fromStyrax agrestisAs Acetylcholinesterase Inhibitors: Structure–Activity Relationships and Molecular Modeling Studies

Journal of Natural Products ◽

10.1021/np200308j ◽

2011 ◽

Vol 74 (10) ◽

pp. 2081-2088 ◽

Cited By ~ 20

Author(s):

Jiawei Liu ◽

Vincent Dumontet ◽

Anne-Laure Simonin ◽

Bogdan I. Iorga ◽

Vincent Guerineau ◽

...

Keyword(s):

Molecular Modeling ◽

Acetylcholinesterase Inhibitors ◽

Structure Activity Relationships ◽

Structure Activity ◽

Modeling Studies ◽

Molecular Modeling Studies

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Thioether-bridged arylalkyl-linked N-phenylpyrazole derivatives: Design, synthesis, insecticidal activities, structure-activity relationship and molecular-modeling studies

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2018.04.022 ◽

2018 ◽

Vol 28 (10) ◽

pp. 1792-1796 ◽

Cited By ~ 2

Author(s):

Chengcheng Fei ◽

Yanfei Chen ◽

Zhiyan Jiang ◽

Dingxin Jiang

Keyword(s):

Molecular Modeling ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Modeling Studies ◽

Molecular Modeling Studies ◽

Insecticidal Activities

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Design, Synthesis, Structure−Activity Relationships, and Molecular Modeling Studies of 2,3-Diaryl-1,3-thiazolidin-4-ones as Potent Anti-HIV Agents

Journal of Medicinal Chemistry ◽

10.1021/jm020977+ ◽

2002 ◽

Vol 45 (24) ◽

pp. 5410-5413 ◽

Cited By ~ 120

Author(s):

Maria L. Barreca ◽

Jan Balzarini ◽

Alba Chimirri ◽

Erik De Clercq ◽

Laura De Luca ◽

...

Keyword(s):

Molecular Modeling ◽

Design Synthesis ◽

Structure Activity Relationships ◽

Structure Activity ◽

Modeling Studies ◽

Molecular Modeling Studies ◽

Anti Hiv Agents ◽

Anti Hiv

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