Compounds from Danshen. Part 4. Structure-activity relationship of miltirone, an active central benzodiazepine receptor ligand isolated from Salvia miltiorrhiza Bunge (Danshen)

Hson Mou Chang; Kuk Ying Chui; Fan Wah Lau Tan; Yun Yang; Zeng Pei Zhong; Chi Ming Lee; Hing Leung Sham; Henry N. C. Wong

doi:10.1021/jm00109a022

Compounds from Danshen. Part 4. Structure-activity relationship of miltirone, an active central benzodiazepine receptor ligand isolated from Salvia miltiorrhiza Bunge (Danshen)

Journal of Medicinal Chemistry ◽

10.1021/jm00109a022 ◽

1991 ◽

Vol 34 (5) ◽

pp. 1675-1692 ◽

Cited By ~ 53

Author(s):

Hson Mou Chang ◽

Kuk Ying Chui ◽

Fan Wah Lau Tan ◽

Yun Yang ◽

Zeng Pei Zhong ◽

...

Keyword(s):

Salvia Miltiorrhiza ◽

Benzodiazepine Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Salvia Miltiorrhiza Bunge ◽

Receptor Ligand ◽

Structure Activity ◽

Central Benzodiazepine Receptor ◽

Relationship Of

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Structure–activity relationship of wedelolactone analogues: Structural requirements for inhibition of Na+,K+-ATPase and binding to the central benzodiazepine receptor

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2006.07.053 ◽

2006 ◽

Vol 14 (23) ◽

pp. 7962-7966 ◽

Cited By ~ 29

Author(s):

Elisa S.C. Pôças ◽

Daniele V.S. Lopes ◽

Alcides J.M. da Silva ◽

Paulo H.C. Pimenta ◽

Fernanda B. Leitão ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structural Requirements ◽

Structure Activity ◽

Central Benzodiazepine Receptor ◽

Relationship Of

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Structure-Activity Relationship of Nuclear Receptor-Ligand Interactions

Current Topics in Medicinal Chemistry ◽

10.2174/1568026033451736 ◽

2003 ◽

Vol 3 (14) ◽

pp. 1573-1599 ◽

Cited By ~ 39

Author(s):

Holger Greschik ◽

Dino Moras

Keyword(s):

Nuclear Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Receptor Ligand ◽

Structure Activity ◽

Ligand Interactions ◽

Relationship Of

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A study of the structure–activity relationship of GABAA–benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2008.08.072 ◽

2008 ◽

Vol 16 (19) ◽

pp. 8853-8862 ◽

Cited By ~ 6

Author(s):

Dongmei Han ◽

F. Holger Försterling ◽

Xiaoyan Li ◽

Jeffrey R. Deschamps ◽

Damon Parrish ◽

...

Keyword(s):

Low Temperature ◽

Conformational Analysis ◽

Benzodiazepine Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Bivalent Ligands ◽

X Ray ◽

Structure Activity ◽

Relationship Of

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Synthesis and structure–activity relationship of 1,2,4-triazole-containing diarylpyrazolyl carboxamide as CB1 cannabinoid receptor–ligand

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.12.040 ◽

2010 ◽

Vol 18 (3) ◽

pp. 1149-1162 ◽

Cited By ~ 14

Author(s):

Hee Jeong Seo ◽

Min Ju Kim ◽

Suk Ho Lee ◽

Sung-Han Lee ◽

Myung Eun Jung ◽

...

Keyword(s):

Cannabinoid Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Receptor Ligand ◽

Cb1 Cannabinoid Receptor ◽

Structure Activity ◽

Relationship Of

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ChemInform Abstract: Synthesis of Diazepam Related Analogues of Miltirone, an Active Central Benzodiazepine Receptor Ligand Isolated from Salvia miltiorrhiza Bunge (Danshen).

ChemInform ◽

10.1002/chin.199112346 ◽

2010 ◽

Vol 22 (12) ◽

pp. no-no

Author(s):

Y. HE ◽

H. M. CHANG ◽

Y. K. LAU ◽

Y. X. CUI ◽

R. J. WANG ◽

...

Keyword(s):

Salvia Miltiorrhiza ◽

Benzodiazepine Receptor ◽

Salvia Miltiorrhiza Bunge ◽

Receptor Ligand ◽

Central Benzodiazepine Receptor

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High affinity central benzodiazepine receptor ligands: synthesis and structure–activity relationship studies of a new series of pyrazolo[4,3- c ]quinolin-3-ones

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(97)10039-6 ◽

1998 ◽

Vol 6 (4) ◽

pp. 389-399 ◽

Cited By ~ 28

Author(s):

L. Savini ◽

P. Massarelli ◽

C. Nencini ◽

C. Pellerano ◽

G. Biggio ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Receptor Ligands ◽

Benzodiazepine Receptor Ligands ◽

High Affinity ◽

Structure Activity ◽

Central Benzodiazepine Receptor

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Synthesis of diazepam related analogues of miltirone, an active central benzodiazepine receptor ligand isolated from Salvia miltiorrhiza bunge (danshen)

Journal of the Chemical Society Perkin Transactions 1 ◽

10.1039/p19900003359 ◽

1990 ◽

pp. 3359 ◽

Cited By ~ 8

Author(s):

Yun He ◽

Hson Mou Chang ◽

Yee Kwan Lau ◽

Yu Xin Cui ◽

Ru Ji Wang ◽

...

Keyword(s):

Salvia Miltiorrhiza ◽

Benzodiazepine Receptor ◽

Salvia Miltiorrhiza Bunge ◽

Receptor Ligand ◽

Central Benzodiazepine Receptor

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Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis

Planta Medica ◽

10.1055/s-0028-1084781 ◽

2008 ◽

Vol 74 (09) ◽

Author(s):

MA Brenzan ◽

CV Nakamura ◽

BPD Filho ◽

T Ueda-Nakamura ◽

MCM Young ◽

...

Keyword(s):

Structure Activity Relationship ◽

Leishmania Amazonensis ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of

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Structure Activity Relationship of Kahalalide F and its Analogs Against Fusarium Spp

Planta Medica ◽

10.1055/s-2008-1075262 ◽

2008 ◽

Vol 74 (03) ◽

Author(s):

N Kasanah ◽

AG Shilabin ◽

DE Wedge ◽

MT Hamann

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Fusarium Spp ◽

Structure Activity ◽

Kahalalide F ◽

Relationship Of

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STRUCTURE-ACTIVITY RELATIONSHIP OF VARIOUS ANALOGUES OF β-CORTICOTRROPHIN DETERMINED BY REFERENCE TO VARIOUS PARAMETERS IN VITRO AND IN VIVO

Acta Endocrinologica ◽

10.1530/acta.0.061s029 ◽

1969 ◽

Vol 61 (1_Suppl) ◽

pp. S29

Author(s):

Pierre A. Desaulles ◽

René Maier ◽

Matthys Staehelin

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of

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