Comparative Molecular Field Analysis of Dopamine D4 Receptor Antagonists Including 3-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 113), 3-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine (L-745,870), and Clozapine

Harald Lanig; Wolfgang Utz; Peter Gmeiner

doi:10.1021/jm001055e

Comparative Molecular Field Analysis of Dopamine D4 Receptor Antagonists Including 3-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 113), 3-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine (L-745,870), and Clozapine

Journal of Medicinal Chemistry ◽

10.1021/jm001055e ◽

2001 ◽

Vol 44 (8) ◽

pp. 1151-1157 ◽

Cited By ~ 28

Author(s):

Harald Lanig ◽

Wolfgang Utz ◽

Peter Gmeiner

Keyword(s):

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Dopamine D4 Receptor ◽

Receptor Antagonists ◽

Molecular Field Analysis ◽

D4 Receptor

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Novel, Potent, and Selective 5-HT3 Receptor Antagonists Based on the Arylpiperazine Skeleton: Synthesis, Structure, Biological Activity, and Comparative Molecular Field Analysis Studies

Journal of Medicinal Chemistry ◽

10.1021/jm00014a021 ◽

1995 ◽

Vol 38 (14) ◽

pp. 2692-2704 ◽

Cited By ~ 59

Author(s):

Maurizio Anzini ◽

Andrea Cappelli ◽

Salvatore Vomero ◽

Gianluca Giorgi ◽

Thierry Langer ◽

...

Keyword(s):

Biological Activity ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Receptor Antagonists ◽

Molecular Field Analysis

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Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA) Studies on α1A-Adrenergic Receptor Antagonists Based on Pharmacophore Molecular Alignment

International Journal of Molecular Sciences ◽

10.3390/ijms12107022 ◽

2011 ◽

Vol 12 (10) ◽

pp. 7022-7037 ◽

Cited By ~ 16

Author(s):

Xin Zhao ◽

Minsheng Chen ◽

Biyun Huang ◽

Hong Ji ◽

Mu Yuan

Keyword(s):

Adrenergic Receptor ◽

Molecular Similarity ◽

Molecular Alignment ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Receptor Antagonists ◽

Molecular Field Analysis ◽

Similarity Indices

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ChemInform Abstract: Novel, Potent, and Selective 5-HT3 Receptor Antagonists Based on the Arylpiperazine Skeleton: Synthesis, Structure, Biological Activity, and Comparative Molecular Field Analysis Studies.

ChemInform ◽

10.1002/chin.199545191 ◽

2010 ◽

Vol 26 (45) ◽

pp. no-no

Author(s):

M. ANZINI ◽

A. CAPPELLI ◽

S. VOMERO ◽

G. GIORGI ◽

T. LANGER ◽

...

Keyword(s):

Biological Activity ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Receptor Antagonists ◽

Molecular Field Analysis

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Comparative molecular field analysis and molecular dynamics studies of the dopamine D2 receptor antagonists without a protonatable nitrogen atom

Medicinal Chemistry Research ◽

10.1007/s00044-018-2137-5 ◽

2018 ◽

Vol 27 (4) ◽

pp. 1149-1166 ◽

Cited By ~ 3

Author(s):

Agnieszka A. Kaczor ◽

Justyna Żuk ◽

Dariusz Matosiuk

Keyword(s):

Molecular Dynamics ◽

Nitrogen Atom ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Receptor Antagonists ◽

Molecular Field Analysis ◽

Dopamine D2

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3D-QSAR Comparative Molecular Field Analysis on Opioid Receptor Antagonists: Pooling Data from Different Studies

Journal of Medicinal Chemistry ◽

10.1021/jm049117e ◽

2005 ◽

Vol 48 (5) ◽

pp. 1620-1629 ◽

Cited By ~ 24

Author(s):

Youyi Peng ◽

Susan M. Keenan ◽

Qiang Zhang ◽

Vladyslav Kholodovych ◽

William J. Welsh

Keyword(s):

Opioid Receptor ◽

3D Qsar ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Receptor Antagonists ◽

Molecular Field Analysis ◽

Opioid Receptor Antagonists

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Flavonoid Derivatives as Adenosine Receptor Antagonists: A Comparison of the Hypothetical Receptor Binding Site Based on a Comparative Molecular Field Analysis Model

Journal of Medicinal Chemistry ◽

10.1021/jm970446z ◽

1998 ◽

Vol 41 (1) ◽

pp. 46-52 ◽

Cited By ~ 35

Author(s):

Stefano Moro ◽

A. Michiel van Rhee ◽

Lawrence H. Sanders ◽

Kenneth A. Jacobson

Keyword(s):

Binding Site ◽

Receptor Binding ◽

Adenosine Receptor ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Analysis Model ◽

Receptor Antagonists ◽

Receptor Binding Site ◽

Molecular Field Analysis

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Comparative molecular field analysis of CCK-A antagonists using field-fit as an alignment technique. A convenient guide to design new CCK-A ligands

Journal of Computer-Aided Molecular Design ◽

10.1007/bf00126214 ◽

1992 ◽

Vol 6 (6) ◽

pp. 553-568 ◽

Cited By ~ 11

Author(s):

Sylvain Rault ◽

Ronan Bureau ◽

Juan Carlos Pilo ◽

Max Robba

Keyword(s):

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Molecular Field Analysis ◽

Alignment Technique

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Comparative Molecular Field Analysis of Compounds with CYP2A5 Binding Affinity

Quantitative Structure-Activity Relationships ◽

10.1002/qsar.19950140603 ◽

1995 ◽

Vol 14 (6) ◽

pp. 507-511 ◽

Cited By ~ 11

Author(s):

Antti Poso ◽

Risto Juvonen ◽

Jukka Gynther

Keyword(s):

Binding Affinity ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Molecular Field Analysis

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3D-QSAR studies on 4-hydroxyphenylpyruvate dioxygenase inhibitors by comparative molecular field analysis (CoMFA)

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(02)00432-8 ◽

2002 ◽

Vol 12 (17) ◽

pp. 2271-2275 ◽

Cited By ~ 18

Author(s):

Meilan Huang ◽

Ding-Yah Yang ◽

Zhicai Shang ◽

Jianwei Zou ◽

Qingsen Yu

Keyword(s):

3D Qsar ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Qsar Studies ◽

Molecular Field Analysis

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Application of comparative molecular field analysis to dopamine d2 partial agonists

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(99)00201-1 ◽

1999 ◽

Vol 7 (11) ◽

pp. 2453-2456 ◽

Cited By ~ 3

Author(s):

Georgia B McGaughey ◽

Richard E Mewshaw

Keyword(s):

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Partial Agonists ◽

Molecular Field Analysis ◽

Dopamine D2

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