Biological activities and quantitative structure-activity relationships of spiro[imidazolidine-4,4'(1'H)-quinazoline]-2,2',5(3'H)-triones as aldose reductase inhibitors

Masafumi Yamagishi; Yoshihisa Yamada; Kenichi Ozaki; Masaaki Asao; Ryo Shimizu; Mamoru Suzuki; Mamoru Matsumoto; Yuzo Matsuoka; Kazuo Matsumoto

doi:10.1021/jm00089a021

Biological activities and quantitative structure-activity relationships of spiro[imidazolidine-4,4'(1'H)-quinazoline]-2,2',5(3'H)-triones as aldose reductase inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm00089a021 ◽

1992 ◽

Vol 35 (11) ◽

pp. 2085-2094 ◽

Cited By ~ 27

Author(s):

Masafumi Yamagishi ◽

Yoshihisa Yamada ◽

Kenichi Ozaki ◽

Masaaki Asao ◽

Ryo Shimizu ◽

...

Keyword(s):

Aldose Reductase ◽

Biological Activities ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Three-dimensional quantitative structure-activity relationships and docking studies of some structurally diverse flavonoids and design of new aldose reductase inhibitors

Journal of Advanced Pharmaceutical Technology amp Research ◽

10.4103/2231-4040.150366 ◽

2015 ◽

Vol 6 (1) ◽

pp. 13 ◽

Cited By ~ 2

Author(s):

Sudhan Debnath ◽

UtpalChandra De ◽

Tanusree Debnath ◽

Debanjan Sen

Keyword(s):

Aldose Reductase ◽

Three Dimensional ◽

Docking Studies ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Structure–activity relationships studies of quinoxalinone derivatives as aldose reductase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.04.047 ◽

2014 ◽

Vol 80 ◽

pp. 383-392 ◽

Cited By ~ 49

Author(s):

Saghir Hussain ◽

Shagufta Parveen ◽

Xin Hao ◽

Shuzhen Zhang ◽

Wei Wang ◽

...

Keyword(s):

Aldose Reductase ◽

Structure Activity Relationships ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quinoxalinone Derivatives

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Applications of neural networks in quantitative structure-activity relationships of dihydrofolate reductase inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm00113a022 ◽

1991 ◽

Vol 34 (9) ◽

pp. 2824-2836 ◽

Cited By ~ 201

Author(s):

T. A. Andrea ◽

Hooshmand Kalayeh

Keyword(s):

Neural Networks ◽

Dihydrofolate Reductase ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Dihydrofolate Reductase Inhibitors

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Quantitative structure–activity relationship of spirosuccinimide type aldose reductase inhibitors diminishing sorbitol accumulation in vivo

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2005.12.019 ◽

2006 ◽

Vol 14 (9) ◽

pp. 3090-3097 ◽

Cited By ~ 6

Author(s):

Kwangseok Ko ◽

Hoshik Won ◽

Youngdo Won

Keyword(s):

Aldose Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity ◽

Relationship Of

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ChemInform Abstract: QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS BY DISTANCE GEOMETRY: SYSTEMATIC ANALYSIS OF DIHYDROFOLATE REDUCTASE INHIBITORS

Chemischer Informationsdienst ◽

10.1002/chin.198042296 ◽

1980 ◽

Vol 11 (42) ◽

Author(s):

G. M. CRIPPEM

Keyword(s):

Dihydrofolate Reductase ◽

Distance Geometry ◽

Quantitative Structure ◽

Systematic Analysis ◽

Structure Activity Relationships ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Dihydrofolate Reductase Inhibitors

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Quantitative structure-activity relationships by distance geometry: systematic analysis of dihydrofolate reductase inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm00180a004 ◽

1980 ◽

Vol 23 (6) ◽

pp. 599-606 ◽

Cited By ~ 35

Author(s):

Gordon M. Crippen

Keyword(s):

Dihydrofolate Reductase ◽

Distance Geometry ◽

Quantitative Structure ◽

Systematic Analysis ◽

Structure Activity Relationships ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Dihydrofolate Reductase Inhibitors

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On the Use of Quantitative Structure Activity Relationships (QSAR) and Global Reactivity Descriptors to Study the Biological Activities of Polychlorinated Biphenyls (PCBs)

Chemometrics Applications and Research ◽

10.1201/b19853-15 ◽

2016 ◽

pp. 327-344

Keyword(s):

Polychlorinated Biphenyls ◽

Biological Activities ◽

Quantitative Structure ◽

Reactivity Descriptors ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Global Reactivity Descriptors

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Evolutionary Neural Networks in Quantitative Structure-Activity Relationships of Dihydrofolate Reductase Inhibitors

Quantitative Structure-Activity Relationships ◽

10.1002/qsar.19960150404 ◽

1996 ◽

Vol 15 (4) ◽

pp. 296-301 ◽

Cited By ~ 11

Author(s):

Jari KyngÃ¤s ◽

Jarkko Valjakka

Keyword(s):

Neural Networks ◽

Dihydrofolate Reductase ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Reductase Inhibitors ◽

Evolutionary Neural Networks ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Dihydrofolate Reductase Inhibitors

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Quantitative structure–activity analysis of 5-arylidene-2,4-thiazolidinediones as aldose reductase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2005.10.069 ◽

2006 ◽

Vol 16 (3) ◽

pp. 512-520 ◽

Cited By ~ 13

Author(s):

S.V. Sambasivarao ◽

Love K. Soni ◽

Arun K. Gupta ◽

P. Hanumantharao ◽

S.G. Kaskhedikar

Keyword(s):

Aldose Reductase ◽

Activity Analysis ◽

Quantitative Structure ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity

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Structure–activity relationships of ganoderma acids from Ganoderma lucidum as aldose reductase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2011.10.035 ◽

2011 ◽

Vol 21 (24) ◽

pp. 7295-7297 ◽

Cited By ~ 22

Author(s):

Sri Fatmawati ◽

Kuniyoshi Shimizu ◽

Ryuichiro Kondo

Keyword(s):

Aldose Reductase ◽

Ganoderma Lucidum ◽

Structure Activity Relationships ◽

Aldose Reductase Inhibitors ◽

Reductase Inhibitors ◽

Structure Activity

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