Novel Non-nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase. 5. 4-Substituted and 2,4-Disubstituted Analogs of Nevirapine

Terence A. Kelly; John R. Proudfoot; Daniel W. McNeil; Usha R. Patel; Eva David; Karl D. Hargrave; Peter M. Grob; Mario Cardozo; Atul Agarwal; Julian Adams

doi:10.1021/jm00024a011

Novel Non-nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase. 5. 4-Substituted and 2,4-Disubstituted Analogs of Nevirapine

Journal of Medicinal Chemistry ◽

10.1021/jm00024a011 ◽

1995 ◽

Vol 38 (24) ◽

pp. 4839-4847 ◽

Cited By ~ 25

Author(s):

Terence A. Kelly ◽

John R. Proudfoot ◽

Daniel W. McNeil ◽

Usha R. Patel ◽

Eva David ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Immunodeficiency Virus ◽

Nucleoside Inhibitors

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Novel Non-nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase. 4. 2-Substituted Dipyridodiazepinones as Potent Inhibitors of Both Wild-Type and Cysteine-181 HIV-1 Reverse Transcriptase Enzymes

Journal of Medicinal Chemistry ◽

10.1021/jm00024a010 ◽

1995 ◽

Vol 38 (24) ◽

pp. 4830-4838 ◽

Cited By ~ 31

Author(s):

John R. Proudfoot ◽

Karl D. Hargrave ◽

Suresh R. Kapadia ◽

Usha R. Patel ◽

Karl G. Grozinger ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Wild Type ◽

Immunodeficiency Virus ◽

Nucleoside Inhibitors ◽

Hiv 1

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Nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase

Current Topics in Medicinal Chemistry ◽

10.2174/1568026043388484 ◽

2004 ◽

Vol 4 (9) ◽

pp. 895-919 ◽

Cited By ~ 50

Author(s):

Prem Sharma ◽

Viktoria Nurpeisov ◽

Brenda Hernandez-Santiago ◽

Thierry Beltran ◽

Raymond Schinazi

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Immunodeficiency Virus ◽

Nucleoside Inhibitors

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Novel Non-Nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase. 6. 2-Indol-3-yl- and 2-Azaindol-3-yl- dipyridodiazepinones1

Journal of Medicinal Chemistry ◽

10.1021/jm960837y ◽

1997 ◽

Vol 40 (15) ◽

pp. 2430-2433 ◽

Cited By ~ 31

Author(s):

Terence A. Kelly ◽

Daniel W. McNeil ◽

Janice M. Rose ◽

Eva David ◽

Cheng-Kon Shih ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Immunodeficiency Virus ◽

Nucleoside Inhibitors

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A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors.

Journal of Clinical Investigation ◽

10.1172/jci4948 ◽

1998 ◽

Vol 102 (10) ◽

pp. 1769-1775 ◽

Cited By ~ 156

Author(s):

M A Winters ◽

K L Coolley ◽

Y A Girard ◽

D J Levee ◽

H Hamdan ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Reverse Transcriptase Gene ◽

Immunodeficiency Virus ◽

Nucleoside Inhibitors

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ChemInform Abstract: Novel Non-Nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase. Part 4. 2-Substituted Dipyridodiazepinones as Potent Inhibitors of Both Wild-Type and Cysteine-181 HIV-1 Reverse Transcriptase Enzym

ChemInform ◽

10.1002/chin.199614181 ◽

2010 ◽

Vol 27 (14) ◽

pp. no-no

Author(s):

J. R. PROUDFOOT ◽

K. D. HARGRAVE ◽

S. R. KAPADIA ◽

U. R. PATEL ◽

K. G. GROZINGER ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Wild Type ◽

Immunodeficiency Virus ◽

Nucleoside Inhibitors ◽

Hiv 1

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Kinetic and mutational analysis of human immunodeficiency virus type 1 reverse transcriptase inhibition by inophyllums, a novel class of non-nucleoside inhibitors.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)37375-1 ◽

1994 ◽

Vol 269 (9) ◽

pp. 6325-6331

Author(s):

P.B. Taylor ◽

J.S. Culp ◽

C. Debouck ◽

R.K. Johnson ◽

A.D. Patil ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Mutational Analysis ◽

Immunodeficiency Virus ◽

Nucleoside Inhibitors

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Inhibition of reverse transcriptase of human immunodeficiency virus type 1 and chimeric enzymes of human immunodeficiency viruses types 1 and 2 by two novel non-nucleoside inhibitors

FEBS Letters ◽

10.1016/0014-5793(94)00793-4 ◽

1994 ◽

Vol 350 (2-3) ◽

pp. 299-303 ◽

Cited By ~ 8

Author(s):

Tami Rubinek ◽

James B. McMahon ◽

Amnon Hizi

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Chimeric Enzymes ◽

Immunodeficiency Virus ◽

Human Immunodeficiency Viruses ◽

Nucleoside Inhibitors

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Effects of Non-nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 in Cell-free Recombinant Reverse Transcriptase Assays

Journal of Biological Chemistry ◽

10.1074/jbc.270.52.31046 ◽

1995 ◽

Vol 270 (52) ◽

pp. 31046-31051 ◽

Cited By ~ 59

Author(s):

Zhengxian Gu ◽

Yudong Quan ◽

Zhou Li ◽

Eric J. Arts ◽

Mark A. Wainberg

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Immunodeficiency Virus ◽

Nucleoside Inhibitors

Download Full-text

ChemInform Abstract: Novel Non-Nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase. Part 5. 4-Substituted and 2,4-Disubstituted Analogues of Nevirapine.

ChemInform ◽

10.1002/chin.199614182 ◽

2010 ◽

Vol 27 (14) ◽

pp. no-no

Author(s):

T. A. KELLY ◽

J. R. PROUDFOOT ◽

D. W. MCNEIL ◽

U. R. PATEL ◽

E. DAVID ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Immunodeficiency Virus ◽

Nucleoside Inhibitors

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Attenuated Replication of Human Immunodeficiency Virus Type 1 with a Didanosine-Selected Reverse Transcriptase Mutation

Journal of Virology ◽

10.1128/jvi.72.4.3504-3504.1998 ◽

1998 ◽

Vol 72 (4) ◽

pp. 3504-3504

Author(s):

Prem L. Sharma ◽

Clyde S. Crumpacker

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Immunodeficiency Virus

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