Sulfonylureas and Sulfonylcarbamates as New Non-Tetrazole Angiotensin II Receptor Antagonists. Discovery of a Highly Potent Orally Active (Imidazolylbiphenylyl)sulfonylurea (HR 720)

1995 ◽  
Vol 38 (13) ◽  
pp. 2357-2377 ◽  
Author(s):  
Pierre Deprez ◽  
Jacques Guillaume ◽  
Reinhard Becker ◽  
Alain Corbier ◽  
Stanislas Didierlaurent ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptor ◽  
Angiotensin Ii Receptor Antagonists ◽  
Receptor Antagonists ◽  
Orally Active

Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists

1991 ◽  
Vol 34 (9) ◽  
pp. 2919-2922 ◽  
Author(s):  
Nathan B. Mantlo ◽  
Prasun K. Chakravarty ◽  
Debra L. Ondeyka ◽  
Peter K. S. Siegl ◽  
Raymond S. Chang ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptor ◽  
Angiotensin Ii Receptor Antagonists ◽  
Receptor Antagonists ◽  
Orally Active

N-3-Substituted Pyrimidinones as Potent, Orally Active, AT1 Selective Angiotensin II Receptor Antagonists

1995 ◽  
Vol 38 (24) ◽  
pp. 4806-4820 ◽  
Author(s):  
Aldo Salimbeni ◽  
Renato Canevotti ◽  
Fabio Paleari ◽  
Davide Poma ◽  
Saturnino Caliari ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptor ◽  
Angiotensin Ii Receptor Antagonists ◽  
Receptor Antagonists ◽  
Orally Active

ChemInform Abstract: Potent and Orally Active Angiotensin II Receptor Antagonists with Equal Affinity for Human AT1 and AT2 Subtypes.

ChemInform ◽  
2010 ◽  
Vol 27 (3) ◽  
pp. no-no
Author(s):  
L. L. CHANG ◽  
W. T. ASHTON ◽  
K. L. FLANAGAN ◽  
T.-B. CHEN ◽  
S. S. OMALLEY ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptor ◽  
Angiotensin Ii Receptor Antagonists ◽  
Receptor Antagonists ◽  
Orally Active

Derivatives of 5-[[1-4(4-carboxybenzyl)imidazolyl]methylidene]hydantoins as orally active angiotensin II receptor antagonists

1995 ◽  
Vol 38 (19) ◽  
pp. 3759-3771 ◽  
Author(s):  
Jeremy J. Edmunds ◽  
Sylvester Klutchko ◽  
James M. Hamby ◽  
Amy M. Bunker ◽  
Cleo J. C. Connolly ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptor ◽  
Angiotensin Ii Receptor Antagonists ◽  
Receptor Antagonists ◽  
Orally Active ◽  
Derivatives Of

Synthesis and SAR Studies of Novel Triazolopyrimidine Derivatives as Potent, Orally Active Angiotensin II Receptor Antagonists

1994 ◽  
Vol 37 (15) ◽  
pp. 2371-2386 ◽  
Author(s):  
Eric Nicolai ◽  
Gerard Cure ◽  
Joel Goyard ◽  
Maud Kirchner ◽  
Jean-Marie Teulon ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptor ◽  
Angiotensin Ii Receptor Antagonists ◽  
Receptor Antagonists ◽  
Sar Studies ◽  
Orally Active

Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives

1991 ◽  
Vol 34 (8) ◽  
pp. 2525-2547 ◽  
Author(s):  
David J. Carini ◽  
John V. Duncia ◽  
Paul E. Aldrich ◽  
Andrew T. Chiu ◽  
Alexander L. Johnson ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptor ◽  
Angiotensin Ii Receptor Antagonists ◽  
Receptor Antagonists ◽  
Orally Active

ChemInform Abstract: N-3-Substituted Pyrimidinones as Potent, Orally Active, AT1 Selective Angiotensin II Receptor Antagonists.

ChemInform ◽  
2010 ◽  
Vol 27 (14) ◽  
pp. no-no
Author(s):  
A. SALIMBENI ◽  
R. CANEVOTTI ◽  
F. PALEARI ◽  
D. POMA ◽  
S. CALIARI ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Angiotensin Ii Receptor ◽  
Angiotensin Ii Receptor Antagonists ◽  
Receptor Antagonists ◽  
Orally Active
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