Sequence-Dependent Drug Binding to the Minor Groove of DNA: Crystal Structure of the DNA Dodecamer d(CGCAAATTTGCG)2 Complexed with Propamidine

Christine M. Nunn; Stephen Neidle

doi:10.1021/jm00013a008

Sequence-Dependent Drug Binding to the Minor Groove of DNA: Crystal Structure of the DNA Dodecamer d(CGCAAATTTGCG)2 Complexed with Propamidine

Journal of Medicinal Chemistry ◽

10.1021/jm00013a008 ◽

1995 ◽

Vol 38 (13) ◽

pp. 2317-2325 ◽

Cited By ~ 45

Author(s):

Christine M. Nunn ◽

Stephen Neidle

Keyword(s):

Crystal Structure ◽

Minor Groove ◽

Drug Binding ◽

Sequence Dependent ◽

Dna Dodecamer

Download Full-text

Lattice- and Sequence-Dependent Binding of Mg2+in the Crystal Structure of a B-DNA Dodecamer

ACS Symposium Series - Nucleic Acids: Curvature and Deformation ◽

10.1021/bk-2004-0884.ch004 ◽

2004 ◽

pp. 87-109 ◽

Cited By ~ 4

Author(s):

Martin Egli ◽

Valentina Tereshko

Keyword(s):

Crystal Structure ◽

Sequence Dependent ◽

Dna Dodecamer

Download Full-text

Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1994.tb18917.x ◽

1994 ◽

Vol 222 (3) ◽

pp. 721-726 ◽

Cited By ~ 71

Author(s):

M. Cristina VEGA ◽

Isabel GARCIA SAEZ ◽

Joan AYMAMI ◽

Ramon ERITJA ◽

Gijs A. MAREL ◽

...

Keyword(s):

Crystal Structure ◽

Three Dimensional ◽

Minor Groove ◽

Minor Groove Binding ◽

Hoechst 33258 ◽

Groove Binding ◽

Dna Dodecamer ◽

Dimensional Crystal

Download Full-text

Faculty Opinions recommendation of Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1107090.563070 ◽

2008 ◽

Author(s):

P Shing Ho

Keyword(s):

Crystal Structure ◽

Minor Groove ◽

Minor Groove Binding ◽

Groove Binding

Download Full-text

Consequences of Replacing the DNA 3‘-Oxygen by an Amino Group: High-Resolution Crystal Structure of a Fully Modified N3‘ → P5‘ Phosphoramidate DNA Dodecamer Duplex†

Journal of the American Chemical Society ◽

10.1021/ja971962h ◽

1998 ◽

Vol 120 (2) ◽

pp. 269-283 ◽

Cited By ~ 66

Author(s):

Valentina Tereshko ◽

Sergei Gryaznov ◽

Martin Egli

Keyword(s):

Crystal Structure ◽

High Resolution ◽

Amino Group ◽

Dna Dodecamer

Download Full-text

The 1.8-Å Crystal Structure of α1-Acid Glycoprotein (Orosomucoid) Solved by UV RIP Reveals the Broad Drug-Binding Activity of This Human Plasma Lipocalin

Journal of Molecular Biology ◽

10.1016/j.jmb.2008.09.020 ◽

2008 ◽

Vol 384 (2) ◽

pp. 393-405 ◽

Cited By ~ 94

Author(s):

Dorian L. Schönfeld ◽

Raimond B.G. Ravelli ◽

Uwe Mueller ◽

Arne Skerra

Keyword(s):

Crystal Structure ◽

Human Plasma ◽

Binding Activity ◽

Drug Binding ◽

Acid Glycoprotein

Download Full-text

The High Resolution Crystal Structure of the Nucleosome Core Particle: Sequence-Dependent DNA-Bending and Plasticity of Histone-DNA Binding

Acta Crystallographica Section A Foundations of Crystallography ◽

10.1107/s0108767300029044 ◽

2000 ◽

Vol 56 (s1) ◽

pp. s439-s439

Author(s):

C. A. Davey ◽

T. J. Richmond

Keyword(s):

Crystal Structure ◽

High Resolution ◽

Dna Binding ◽

Dna Bending ◽

Core Particle ◽

Nucleosome Core Particle ◽

Nucleosome Core ◽

Sequence Dependent

Download Full-text

Crystal structure of a B-DNA dodecamer containing inosine, d(CGCIAATTCGCG), at 2.4 Å resolution and its comparison with other B-DNA dodecamers

Nucleic Acids Research ◽

10.1093/nar/20.20.5457 ◽

1992 ◽

Vol 20 (20) ◽

pp. 5457-5464 ◽

Cited By ~ 35

Author(s):

Jian-Cheng Xuan ◽

Irene T. Weber

Keyword(s):

Crystal Structure ◽

Dna Dodecamer

Download Full-text

Crystal Structure of a Left-Handed Z-DNA Hexamer, d(CG)3, Duplex Complexed with Synthetic Polyamine Reveals Binding of a Polyamine in the Minor Groove

Nucleosides and Nucleotides ◽

10.1080/07328319908044786 ◽

1999 ◽

Vol 18 (6-7) ◽

pp. 1567-1569

Author(s):

Ken-Ichi Tomita ◽

Hirofumi Ohishi ◽

Isao Nakanishi ◽

Toshio Hakoshima ◽

Alexander Rich

Keyword(s):

Crystal Structure ◽

Minor Groove ◽

Left Handed ◽

Z Dna

Download Full-text

Crystal structure of the highly distorted chimeric decamer r(C)d(CGGCGCCG)r(G).spermine complex — spermine binding to phosphate only and minor groove tertiary base-pairing

Nucleic Acids Research ◽

10.1093/nar/22.24.5466 ◽

1994 ◽

Vol 22 (24) ◽

pp. 5466-5476 ◽

Cited By ~ 16

Author(s):

Changill Ban ◽

B. Ramakrishnan ◽

M. Sundaralingam

Keyword(s):

Crystal Structure ◽

Minor Groove ◽

Base Pairing

Download Full-text

Crystal Structure of gamma-Oxapentamidine Complexed with d(CGCGAATTCGCG)2. The Effects of Drug Structural Change on DNA Minor-Groove Recognition

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1994.00953.x ◽

1994 ◽

Vol 226 (3) ◽

pp. 953-961 ◽

Cited By ~ 17

Author(s):

Christine M. Nunn ◽

Terence C. Jenkins ◽

Stephen Neidle

Keyword(s):

Crystal Structure ◽

Structural Change ◽

Minor Groove ◽

Dna Minor Groove

Download Full-text