Effect of Dietary Conjugated Linoleic Acid on Lipid Peroxidation and Histological Change in Rat Liver Tissues

2000 ◽  
Vol 48 (12) ◽  
pp. 6367-6371 ◽  
Author(s):  
Masao Yamasaki ◽  
Keiko Mansho ◽  
Hiroko Mishima ◽  
Genki Kimura ◽  
Masafumi Sasaki ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Rat Liver ◽  
Histological Change ◽  
Dietary Conjugated Linoleic Acid ◽  
Liver Tissues

Dietary conjugated linoleic acid reciprocally modifies ketogenesis and lipid secretion by the rat liver

Lipids ◽  
1999 ◽  
Vol 34 (9) ◽  
pp. 997-1000 ◽  
Author(s):  
Masanobu Sakono ◽  
Fumiko Miyanaga ◽  
Satoshi Kawahara ◽  
Kiyoshi Yamauchi ◽  
Nobuhiro Fukuda ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Rat Liver ◽  
Lipid Secretion ◽  
Dietary Conjugated Linoleic Acid

scholarly journals Combined Effects of Dietary Conjugated Linoleic Acid and Sesamin on Triacylglycerol and Ketone Body Production in Rat Liver.

2002 ◽  
Vol 48 (5) ◽  
pp. 405-409 ◽  
Author(s):  
Masanobu SAKONO ◽  
Kumiko YUJI ◽  
Fumiko MIYANAGA ◽  
Shizuka TAMARU ◽  
Michiko FUJITA ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Rat Liver ◽  
Ketone Body ◽  
Combined Effects ◽  
Dietary Conjugated Linoleic Acid ◽  
Body Production

scholarly journals Dietary Conjugated Linoleic Acid Reduces Lipid Peroxidation by Increasing Oxidative Stability in Rats

2005 ◽  
Vol 51 (1) ◽  
pp. 8-15 ◽  
Author(s):  
Hye-Kyeong KIM ◽  
Sung-Ran KIM ◽  
Ji-Yoon AHN ◽  
Il-Jin CHO ◽  
Chil-Suk YOON ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Linoleic Acid ◽  
Oxidative Stability ◽  
Conjugated Linoleic Acid ◽  
Dietary Conjugated Linoleic Acid

scholarly journals Dietary conjugated linoleic acid isomers and selenium affect the fatty acid profile in rat liver

2005 ◽  
Vol 14 (Suppl. 1) ◽  
pp. 533-536
Author(s):  
M. Czauderna ◽  
J. Kowalczyk ◽  
K. Korniluk ◽  
I. Wąsowska ◽  
B. Pastuszewska
Keyword(s):  
Fatty Acid ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Fatty Acid Profile ◽  
Rat Liver ◽  
Dietary Conjugated Linoleic Acid

scholarly journals Distribution of conjugated linoleic acid and metabolites in different lipid fractions in the rat liver

2001 ◽  
Vol 42 (7) ◽  
pp. 1056-1061 ◽  
Author(s):  
Sebastiano Banni ◽  
Gianfranca Carta ◽  
Elisabetta Angioni ◽  
Elisabettta Murru ◽  
Paolo Scanu ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Rat Liver ◽  
Lipid Fractions

scholarly journals Dietary conjugated linoleic acid (CLA) induces apoptosis of colonic mucosa in 1,2-dimethylhydrazine-treated rats: a possible mechanism of the anticarcinogenic effect by CLA

2001 ◽  
Vol 86 (5) ◽  
pp. 549-555 ◽  
Author(s):  
Hyun S. Park ◽  
Ji H. Ryu ◽  
Yeong L. Ha ◽  
Jung H. Y. Park
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Control Diet ◽  
Terminal Deoxynucleotidyl Transferase ◽  
Prostaglandin E ◽  
Dependent Manner ◽  
Sprague Dawley ◽  
Tumour Incidence ◽  
Sprague Dawley Rats ◽  
Dietary Conjugated Linoleic Acid

One of the objectives of the present study was to investigate whether 1 % conjugated linoleic acid (CLA) in the diet reduced tumour incidence in the colon of 1,2-dimethylhydrazine (DMH)-treated rats. Colon cancer was induced by injecting 6-week-old, male, Sprague–Dawley rats with 15 mg/kg DMH twice per week for 6 weeks. They were fed either 1 % CLA or a control diet ad libitum for 30 weeks. Dietary CLA significantly decreased colon tumour incidence (P<0·05). Our second objective was to investigate whether apoptosis in the colon mucosa of DMH-treated rats was affected by the amount of dietary CLA and whether the changes in apoptosis were related to those in fatty acid-responsive biomarkers. For this purpose, rats were killed after being fed a diet containing 0 %, 0·5 %, 1 % or 1·5 % CLA for 14 weeks. CLA was undetected in the mucosa of rats fed the 0 % CLA diet and increased to 5·9 mg/g phospholipid in rats fed the 0·5 % diet. The apoptotic index estimated by the terminal deoxynucleotidyl transferase-mediated dUTP nick and labelling technique was increased by 251 % and the 1,2-diacylglycerol content was decreased by 57 % in rats fed 0·5 % CLA. No further changes in these variables were observed when CLA in the diet was raised to 1·0 % or 1·5 %. However, dietary CLA decreased mucosal levels of prostaglandin E2, thromboxane B2 and arachidonic acid in a dose-dependent manner. The present data indicate that dietary CLA can inhibit DMH-induced colon carcinogenesis by mechanisms probably involving increased apoptosis.

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