Formation of Sulfur-Containing Flavor Compounds from Reactions of Furaneol and Cysteine, Glutathione, Hydrogen Sulfide, and Alanine/Hydrogen Sulfide

1997 ◽  
Vol 45 (3) ◽  
pp. 894-897 ◽  
Author(s):  
Yan Zheng ◽  
Sharon Brown ◽  
Walter O. Ledig ◽  
Cynthia Mussinan ◽  
Chi-Tang Ho
Keyword(s):  
Hydrogen Sulfide ◽  
Flavor Compounds ◽  
Sulfur Containing

scholarly journals Hydrogen Sulfide Gas Exposure Induces Necroptosis and Promotes Inflammation through the MAPK/NF-κB Pathway in Broiler Spleen

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Qianru Chi ◽  
Dongxu Wang ◽  
Xueyuan Hu ◽  
Shiping Li ◽  
Shu Li
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Sulfide ◽  
Energy Metabolism ◽  
Inflammatory Response ◽  
Human Health ◽  
Mapk Pathway ◽  
Classical Pathway ◽  
Inos Activity ◽  
Mda Content ◽  
Sulfur Containing

Hydrogen sulfide (H2S) is one of the main pollutants in the atmosphere, which is a serious threat to human health. The decomposition of sulfur-containing organics in chicken houses could produce a large amount of H2S, thereby damaging poultry health. In this study, one-day-old broilers were selected and exposed to 4 or 20 ppm of H2S gas (0-3 weeks: 4±0.5 ppm, 4-6 weeks: 20±0.5 ppm). The spleen samples were collected immediately after the chickens were euthanized at 2, 4, and 6 weeks. The histopathological and ultrastructural observations showed obvious necrosis characteristics of H2S-exposed spleens. H2S exposure suppressed GSH, CAT, T-AOC, and SOD activities; increased NO, H2O2, and MDA content and iNOS activity; and induced oxidative stress. ATPase activities and the expressions of energy metabolism-related genes were significantly decreased. Also, the expressions of related necroptosis (RIPK1, RIPK3, MLKL, TAK1, TAB2, and TAB3) were significantly increased, and the MAPK pathway was activated. Besides, H2S exposure activated the NF-κB classical pathway and induced TNF-α and IL-1β release. Taken together, we conclude that H2S exposure induces oxidative stress and energy metabolism dysfunction; evokes necroptosis; activates the MAPK pathway, eventually triggering the NF-κB pathway; and promotes inflammatory response in chicken spleens.

Identification and formation of some selected sulfur-containing flavor compounds in various meat model systems

1990 ◽  
Vol 38 (11) ◽  
pp. 2027-2041 ◽  
Author(s):  
Matthias Guentert ◽  
Juergen Bruening ◽  
Roland Emberger ◽  
Manfred Koepsel ◽  
Walter Kuhn ◽  
...  
Keyword(s):  
Model Systems ◽  
Flavor Compounds ◽  
Sulfur Containing

Characterization of novel, sulfur-containing Maillard flavor compounds

2002 ◽  
Vol 1245 ◽  
pp. 229-233 ◽  
Author(s):  
Peter Schieberle ◽  
Wolfgang Engel
Keyword(s):  
Flavor Compounds ◽  
Sulfur Containing

scholarly journals Immunomodulatory Effects of Glutathione, Garlic Derivatives, and Hydrogen Sulfide

Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 295 ◽  
Author(s):  
Camila Rodrigues ◽  
Susan Percival
Keyword(s):  
Cardiovascular Disease ◽  
Hydrogen Sulfide ◽  
Aged Garlic Extract ◽  
Immunomodulatory Effects ◽  
Beneficial Effects ◽  
Health And Disease ◽  
Oxidative Processes ◽  
Sulfur Containing ◽  
Aged Garlic ◽  
Sulfur Containing Compounds

Glutathione and aged garlic extract are sulfur-containing products that play important protective and regulatory roles within the immune system and in oxidative processes. Hydrogen sulfide (H2S), an endogenous, gaseous, signaling transmitter, has also been shown to be involved in the regulation of inflammation. Recent studies have shown that sulfur-containing compounds from garlic have beneficial effects in attenuating outcomes associated with cardiovascular disease and inflammation by a mechanism that may be related to the H2S signaling pathway. In this review, we summarize the main functions of glutathione (GSH), garlic derivatives and H2S and their role in the immune response and impact on health and disease.

Metabolic Imbalance of Homocysteine and Hydrogen Sulfide in Kidney Disease

2018 ◽  
Vol 25 (3) ◽  
pp. 367-377 ◽  
Author(s):  
Karmin O ◽  
Yaw L. Siow
Keyword(s):  
Hydrogen Sulfide ◽  
Kidney Disease ◽  
Molecular Mechanisms ◽  
Ischemia Reperfusion ◽  
Kidney Injury ◽  
Cerebral Dysfunction ◽  
Transsulfuration Pathway ◽  
Metabolic Imbalance ◽  
Common Clinical Finding ◽  
Sulfur Containing

Homocysteine (Hcy) and hydrogen sulfide (H2S) are important molecules produced during the metabolism of sulfur-containing amino acids. Hcy metabolism is central to the supply of methyl groups that are essential for biological function. Hcy can be either regenerated to methionine or metabolized to cysteine, a precursor for glutathione synthesis. Cystathionine-β-synthase (CBS) and cystathionine-γ-lyase (CSE) play a crucial role in metabolizing Hcy to cysteine through the transsulfuration pathway. These two enzymes are also responsible for H2S generation through desulfuration reactions. H2S, at physiological levels serves as a gaseous mediator and has multifaceted effects. Metabolic imbalance of Hcy and H2S has been implicated in pathological conditions including oxidative stress, inflammation, cardiovascular and cerebral dysfunction, fatty liver disease and ischemiareperfusion injury. Organs such as liver, kidney, gut and pancreas contain all the enzymes that are required for Hcy metabolism. The kidney plays an important role in removing Hcy from the circulation. Hyperhomocysteinemia, a condition of elevated blood Hcy level, is a common clinical finding in patients with chronic kidney disease (CKD) or acute kidney injury (AKI), the latter is often caused by ischemia-reperfusion. This paper reviews exiting literatures regarding (1) the role of kidney in regulating Hcy and H2S metabolism; (2) disruption of sulfur-containing amino acid metabolism during ischemiareperfusion; (3) impact of metabolic imbalance of Hcy and H2S on kidney function. Better understanding of molecular mechanisms that regulate Hcy and H2S metabolism under physiological and pathophysiological conditions will help improve therapeutic strategies for patients with kidney disease or other organ injuries.

Solving Problems of High Temperature Sulfur Corrosion at Crude Oil Processing Units

2021 ◽  
Vol 626 (4) ◽  
pp. 33-37
Author(s):  
A. V. Lozinskii ◽  
◽  
D. P. Kuchin ◽  
V. N. Efimov ◽  
M. I. Pakhomova ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
High Temperature ◽  
Crude Oil ◽  
Oil Extraction ◽  
Corrosion Condition ◽  
Oil Processing ◽  
Sulfur Containing

This article reveals the influence of natural sulfur containing oil compounds on corrosion condition of equipment. It is described that the main reason of rapid increase of oil corrosion aggressiveness recently is application of reagents at the stage of oil extraction and transportation to bind hydrogen sulfide and mercaptans. Several solutions are suggested to solve the problem of high temperature sulfur corrosion on crude oil processing units with account of problematic zones isolation.

Antioxidative Activity of Sulfur-containing Flavor Compounds in Garlic

1997 ◽  
Vol 61 (9) ◽  
pp. 1482-1485 ◽  
Author(s):  
Sun Min Kim ◽  
Kikue Kubota ◽  
Akio Kobayashi
Keyword(s):  
Antioxidative Activity ◽  
Flavor Compounds ◽  
Sulfur Containing
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