Stereoisomeric Separation and Bioassay of a New Organophosphorus Compound,O,S-Dimethyl-N-(2,2,2-trichloro-1-methoxyethyl)phosphoramidothioate: Some Implications for Chiral Switch

2009 ◽  
Vol 57 (15) ◽  
pp. 6920-6926 ◽  
Author(s):  
Shanshan Zhou ◽  
Lumei Wang ◽  
Ling Li ◽  
Weiping Liu
Keyword(s):  
Organophosphorus Compound ◽  
Stereoisomeric Separation

scholarly journals Profile of Organophosphorus Poisoning

KYAMC Journal ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 133-135
Author(s):  
Joya Debnath ◽  
Arpan Kumar Basak ◽  
Md Zubaidur Rahman ◽  
Anujit Saha
Keyword(s):  
Organophosphorus Compound ◽  
Economic Status ◽  
Frequency Pattern ◽  
Major Health Problem ◽  
Major Health ◽  
The Public ◽  
Medical College ◽  
Phosphorus Poisoning ◽  
Life Threatening ◽  
The Government

Background : Self poisoning with organophosphate pesticides is a major health problem in world wide. Organophosphorus compound poisoning is a very common toxicological emergency encountered at Mirzapur in Tangail. It is particularly common among the rural agricultural worker's which comprise a substantial group of the population of this region.Objective: The objective of this study was to find out the incidence, frequency, pattern of poisoning, outcome and aetiological aspect of Organo phosphorus poisoning patient admitted in Kumudini Women's Medical college Hospital.Methods: A total 366 cases of OPC poisoning were analysed during 1 year from January 2015 to December 2015. The emphasis was given on age, sex, socio-economic status, occupation, motive of poisoning, types of compound consumed its quality, place, distance from referral place and the ultimate outcome.Results: Young population of rural background, particularly agricultural workers were the commonest patients (51.91%). The most common motive of poisoning was with a suicidal intent, both in males (27.59%) and females (66.39%). Financial crisis was one of the most common reasons analysed as the motive behind the poisoning (54.20%). Three hundred forty four Patients recovered and 22 were expired. The major cause of death in these cases was respiratory failure followed by multi-organ failure.Conclusion : Strict of the pesticide act and involving a new policy by the government to educate the public and youth in large about the dangerous, life threatening effects of Organophosphorus compound could help amelerioating the harmful effects of such poisoning.KYAMC Journal Vol. 9, No.-3, October 2018, Page 133-135

scholarly journals Teratogenic Effects of the Organophosphorus Compound Fenchlorphos in Rabbits

1983 ◽  
Vol 24 (3) ◽  
pp. 295-304
Author(s):  
I. Nafstad ◽  
G. Berge ◽  
E. Sannes ◽  
A. Lyngset
Keyword(s):  
Organophosphorus Compound ◽  
Teratogenic Effects

Inhibition of Aflatoxin Biosynthesis by Organophosphorus Compounds

1980 ◽  
Vol 43 (5) ◽  
pp. 381-384 ◽  
Author(s):  
M. F. DUTTON ◽  
M. S. ANDERSON
Keyword(s):  
Aspergillus Flavus ◽  
Organophosphorus Compound ◽  
Organophosphorus Compounds ◽  
Culture Fluid ◽  
Aflatoxin Production ◽  
The Other ◽  
Aflatoxin Biosynthesis ◽  
Inhibition Effect ◽  
Type Activity ◽  
Acetate Derivative

The effect of a range of organophosphorus and various other compounds on production of aflatoxin by Aspergillus flavus was investigated. Five organophosphorus compounds - Chlormephos, Ciodrin, Naled, Phosdrin and Trichlorphon- at concentrations of 20 and 100 μg/ml of culture fluid were found to have activity similar to Dichlorvos, in that they lowered the level of aflatoxin produced and caused formation of several anthraquinone pigments. Two of these pigments have not previously been described, one was named Versicol and a suggested structure is presented, whilst the other compound was shown to be its acetate derivative. A rationale is suggested for the required elements of structure, which are necessary for an organophosphorus compound to have Dichlorvos-type activity. Two unrelated compounds, ammonium nitrate and Tridecanone were also found to elicit Dichlorvos-type activity. It is likely that tridecanone or its breakdown products competitively inhibit enzymes involved in aflatoxin biosynthesis. It is possible that this inhibition effect explains the lowering of aflatoxin production in lipid-rich commodities infected by A. flavus.

Investigation of the Ability of the Organophosphorus Compound Tetrakis(2,4-Di-Tert-Butylphenyl)-4,4'-Biphenyl Diphosphonite to Polyetheretherketone Stabilize

2020 ◽  
Vol 869 ◽  
pp. 544-549
Author(s):  
Albert S. Shabaev ◽  
Elina V. Khakyasheva ◽  
Ruslan A. Shetov ◽  
Svetlana Yu. Khashirova
Keyword(s):  
Gas Chromatography ◽  
Organophosphorus Compound ◽  
Extrusion Processing ◽  
Polyether Ether Ketone ◽  
Operational Characteristics ◽  
Stabilizing Effect ◽  
Ether Ketone

The method of gas chromatography was used to study of the stabilizing effect of the organophosphorus compound tetrakis (2,4-di-tert-butylphenyl)-4,4-biphenyl diphosphonite on polyether ether ketone. The possibility of maintaining the structure of polyetheretherketone under conditions of its extrusion processing without the risk of deterioration of the main technological and operational characteristics is revealed.

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