Capsaicinoids but Not Their Analogue Capsinoids Lower Plasma Cholesterol and Possess Beneficial Vascular Activity

2014 ◽  
Vol 62 (33) ◽  
pp. 8415-8420 ◽  
Author(s):  
Weihuan Huang ◽  
Wai San Cheang ◽  
Xiaobo Wang ◽  
Lin Lei ◽  
Yuwei Liu ◽  
...  
Keyword(s):  
Plasma Cholesterol ◽  
Lower Plasma ◽  
Vascular Activity ◽  
Lower Plasma Cholesterol

scholarly journals Low Levels of Viscous Hydrocolloids Lower Plasma Cholesterol in Rats Primarily by Impairing Cholesterol Absorption

2000 ◽  
Vol 130 (2) ◽  
pp. 243-248 ◽  
Author(s):  
Marie-Anne Levrat-Verny ◽  
Stephen Behr ◽  
Vikkie Mustad ◽  
Christian Rémésy ◽  
Christian Demigné
Keyword(s):  
Plasma Cholesterol ◽  
Cholesterol Absorption ◽  
Lower Plasma ◽  
Lower Plasma Cholesterol ◽  
Low Levels

scholarly journals Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice1–3

2006 ◽  
Vol 84 (2) ◽  
pp. 312-321 ◽  
Author(s):  
Ilse Duivenvoorden ◽  
Peter J Voshol ◽  
Patrick CN Rensen ◽  
Wim van Duyvenvoorde ◽  
Johannes A Romijn ◽  
...  
Keyword(s):  
Plasma Cholesterol ◽  
Liver Steatosis ◽  
Lower Plasma ◽  
Lower Plasma Cholesterol

Wheat germ policosanol failed to lower plasma cholesterol in subjects with normal to mildly elevated cholesterol concentrations

Metabolism ◽  
2004 ◽  
Vol 53 (10) ◽  
pp. 1309-1314 ◽  
Author(s):  
Yuguang Lin ◽  
Mike Rudrum ◽  
Reggy P.J. van der Wielen ◽  
Elke A. Trautwein ◽  
Gerald McNeill ◽  
...  
Keyword(s):  
Wheat Germ ◽  
Plasma Cholesterol ◽  
Lower Plasma ◽  
Elevated Cholesterol ◽  
Lower Plasma Cholesterol

The soybean protein diet does not lower plasma cholesterol?

1981 ◽  
Vol 38 (3-4) ◽  
pp. 423-425 ◽  
Author(s):  
Cesare R. Sirtori ◽  
Giancarlo Descovich ◽  
Giorgio Noseda
Keyword(s):  
Soybean Protein ◽  
Plasma Cholesterol ◽  
Protein Diet ◽  
Lower Plasma ◽  
Lower Plasma Cholesterol

scholarly journals Hypocholesterolaemic effects of plant sterol analogues are independent of ABCG5 and ABCG8 transporter expressions in hamsters

2007 ◽  
Vol 98 (3) ◽  
pp. 550-555 ◽  
Author(s):  
Xiaoming Jia ◽  
Naoyuki Ebine ◽  
Isabelle Demonty ◽  
Yanwen Wang ◽  
Robin Beech ◽  
...  
Keyword(s):  
Small Intestine ◽  
Mrna Expression ◽  
Plant Sterol ◽  
Plasma Cholesterol ◽  
Plant Sterols ◽  
Lower Plasma ◽  
Plant Stanols ◽  
Cholesterol Levels ◽  
Lower Plasma Cholesterol ◽  
Reduce Plasma Cholesterol

The hypolipidaemic effects of plant sterols are well established. However, mechanisms by which plant sterols lower plasma cholesterol levels, particularly at the molecular level, have not been clearly elucidated. The objective of the present study was to determine whether different plant sterol analogues reduce plasma cholesterol levels by up regulating the sterol transporters ABCG5 and ABCG8 in the liver and/or small intestine. Male Golden Syrian hamsters were divided into eight groups. Groups 1 and 2 were fed a maize starch–casein–sucrose-based diet that did not contain cholesterol (control; Con) or the Con diet with the addition of 0·25 % cholesterol (Ch-Con). Groups 3–8 were fed the Ch-Con diet supplemented with 1 % plant sterols, 1 % plant stanols, 1 % of a plant sterol and stanol mixture (50:50), 1·76 % plant sterol–fish oil esters, or 0·71 or 1·43 % stanol–ascorbic acid esters, respectively. After 5 weeks, the Ch-Con diet up regulated the ABCG5 mRNA expression and tended (P = 0·083) to increase ABCG8 mRNA expression in the liver, but did not affect both genes’ expression in the small intestine compared with the Con diet. Hamsters fed 0·7 % stanol esters showed lower plasma cholesterol levels (P < 0·001) and also lower liver ABCG5 mRNA expression (P < 0·05) compared with the Ch-Con diet. Plant stanols, stanol esters, and sterol esters did not affect the ABCG5 or ABCG8 mRNA expressions in the liver and intestine although they reduced plasma cholesterol levels. These results suggest that plant sterols and their derivatives reduce plasma cholesterol levels independently from the mRNA expression of ABCG5 and ABCG8 transporters.

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