The Gut Microbiota Ellagic Acid-Derived Metabolite Urolithin A and Its Sulfate Conjugate Are Substrates for the Drug Efflux Transporter Breast Cancer Resistance Protein (ABCG2/BCRP)

Antonio González-Sarrías; Verónica Miguel; Gracia Merino; Ricardo Lucas; Juan C. Morales; Francisco Tomás-Barberán; Ana I. Álvarez; Juan C. Espín

doi:10.1021/jf4007505

The Gut Microbiota Ellagic Acid-Derived Metabolite Urolithin A and Its Sulfate Conjugate Are Substrates for the Drug Efflux Transporter Breast Cancer Resistance Protein (ABCG2/BCRP)

Journal of Agricultural and Food Chemistry ◽

10.1021/jf4007505 ◽

2013 ◽

Vol 61 (18) ◽

pp. 4352-4359 ◽

Cited By ~ 33

Author(s):

Antonio González-Sarrías ◽

Verónica Miguel ◽

Gracia Merino ◽

Ricardo Lucas ◽

Juan C. Morales ◽

...

Keyword(s):

Breast Cancer ◽

Gut Microbiota ◽

Ellagic Acid ◽

Breast Cancer Resistance Protein ◽

Drug Efflux ◽

Efflux Transporter ◽

Cancer Resistance ◽

Urolithin A ◽

Resistance Protein ◽

Sulfate Conjugate

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The effects of human immunodeficiency virus infection on the expression of the drug efflux proteins P-glycoprotein and breast cancer resistance protein in a human intestine model

Journal of Pharmacy and Pharmacology ◽

10.1111/jphp.12329 ◽

2014 ◽

Vol 67 (2) ◽

pp. 178-188 ◽

Cited By ~ 4

Author(s):

Kelstan Ellis ◽

Jerry W. Marlin ◽

Tracey A.H. Taylor ◽

Sylvia Fitting ◽

Kurt F. Hauser ◽

...

Keyword(s):

Breast Cancer ◽

Human Immunodeficiency Virus ◽

Virus Infection ◽

Breast Cancer Resistance Protein ◽

Drug Efflux ◽

Human Intestine ◽

Cancer Resistance ◽

P Glycoprotein ◽

Immunodeficiency Virus ◽

Resistance Protein

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Role of breast cancer resistance protein (BCRP) as active efflux transporter on blood-brain barrier (BBB) permeability

Molecular Diversity ◽

10.1007/s11030-014-9562-2 ◽

2014 ◽

Vol 19 (1) ◽

pp. 163-172 ◽

Cited By ~ 18

Author(s):

Prabha Garg ◽

Rahul Dhakne ◽

Vilas Belekar

Keyword(s):

Breast Cancer ◽

Blood Brain Barrier ◽

Breast Cancer Resistance Protein ◽

Brain Barrier ◽

Efflux Transporter ◽

Cancer Resistance ◽

Active Efflux ◽

Blood Brain ◽

Resistance Protein

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Efflux transporter breast cancer resistance protein dominantly expresses on the membrane of red blood cells, hinders partitioning of its substrates into the cells, and alters drug–drug interaction profiles

Xenobiotica ◽

10.1080/00498254.2017.1397812 ◽

2017 ◽

Vol 48 (11) ◽

pp. 1173-1183 ◽

Cited By ~ 4

Author(s):

Pu Shi ◽

Mingxiang Liao ◽

Bei-Ching Chuang ◽

Robert Griffin ◽

Judy Shi ◽

...

Keyword(s):

Breast Cancer ◽

Drug Interaction ◽

Red Blood Cells ◽

Blood Cells ◽

Breast Cancer Resistance Protein ◽

Efflux Transporter ◽

Cancer Resistance ◽

Resistance Protein ◽

Drug Drug Interaction

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Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2)

Food Chemistry ◽

10.1016/j.foodchem.2012.12.021 ◽

2013 ◽

Vol 138 (4) ◽

pp. 2267-2274 ◽

Cited By ~ 59

Author(s):

Kee W. Tan ◽

Yan Li ◽

James W. Paxton ◽

Nigel P. Birch ◽

Arjan Scheepens

Keyword(s):

Breast Cancer ◽

Breast Cancer Resistance Protein ◽

Efflux Transporter ◽

Cancer Resistance ◽

Dietary Phytochemicals ◽

Resistance Protein

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Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization

International Journal of Cancer ◽

10.1002/ijc.10100 ◽

2002 ◽

Vol 97 (5) ◽

pp. 626-630 ◽

Cited By ~ 193

Author(s):

Kumie Kage ◽

Satomi Tsukahara ◽

Tomomi Sugiyama ◽

Sakiyo Asada ◽

Etsuko Ishikawa ◽

...

Keyword(s):

Breast Cancer ◽

Breast Cancer Resistance Protein ◽

Efflux Pump ◽

Dominant Negative ◽

Drug Efflux ◽

Cancer Resistance ◽

Resistance Protein ◽

Drug Efflux Pump

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Improvement of the Oral Drug Absorption of Topotecan through the Inhibition of Intestinal Xenobiotic Efflux Transporter, Breast Cancer Resistance Protein, by Excipients

Drug Metabolism and Disposition ◽

10.1124/dmd.106.014217 ◽

2007 ◽

Vol 35 (7) ◽

pp. 1142-1148 ◽

Cited By ~ 71

Author(s):

Tetsuo Yamagata ◽

Hiroyuki Kusuhara ◽

Mariko Morishita ◽

Kozo Takayama ◽

Hassan Benameur ◽

...

Keyword(s):

Breast Cancer ◽

Drug Absorption ◽

Breast Cancer Resistance Protein ◽

Oral Drug ◽

Efflux Transporter ◽

Cancer Resistance ◽

Oral Drug Absorption ◽

Resistance Protein

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Intestinal breast cancer resistance protein (BCRP) requires Janus kinase 3 activity for drug efflux and barrier functions in obesity

Journal of Biological Chemistry ◽

10.1074/jbc.ra119.007758 ◽

2019 ◽

Vol 294 (48) ◽

pp. 18337-18348 ◽

Cited By ~ 4

Author(s):

Jayshree Mishra ◽

Randall Simonsen ◽

Narendra Kumar

Keyword(s):

Breast Cancer ◽

Breast Cancer Resistance Protein ◽

Janus Kinase ◽

Drug Efflux ◽

Cancer Resistance ◽

Barrier Functions ◽

Resistance Protein ◽

Janus Kinase 3

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Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-10-0438 ◽

2011 ◽

Vol 10 (1) ◽

pp. 117-125 ◽

Cited By ~ 11

Author(s):

Xiaonan Hou ◽

Fei Huang ◽

Joan M. Carboni ◽

Karen Flatten ◽

Yan W. Asmann ◽

...

Keyword(s):

Breast Cancer ◽

Growth Factor ◽

Insulin Receptor ◽

Breast Cancer Resistance Protein ◽

Growth Factor Receptor ◽

Drug Efflux ◽

Cancer Resistance ◽

Mechanism Of Resistance ◽

Resistance Protein ◽

Receptor Inhibitor

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Ginkgo biloba leaf extract suppresses intestinal human breast cancer resistance protein expression in mice: Correlation with gut microbiota

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2021.111712 ◽

2021 ◽

Vol 140 ◽

pp. 111712

Author(s):

Jeon-Kyung Kim ◽

Min Sun Choi ◽

Jae-Young Kim ◽

Jun Sang Yu ◽

Jeong In Seo ◽

...

Keyword(s):

Breast Cancer ◽

Gut Microbiota ◽

Human Breast Cancer ◽

Breast Cancer Resistance Protein ◽

Leaf Extract ◽

Cancer Resistance ◽

Human Breast ◽

Resistance Protein ◽

Ginkgo Biloba Leaf Extract ◽

Ginkgo Biloba Leaf

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Drug efflux by breast cancer resistance protein (BCRP) is a mechanism of resistance to the insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924.

10.1158/0008-5472.sabcs-2149 ◽

2009 ◽

Author(s):

P Haluska ◽

JM Carboni ◽

YW Asmann ◽

C Ten Eyck ◽

RM Attar ◽

...

Keyword(s):

Breast Cancer ◽

Growth Factor ◽

Insulin Receptor ◽

Breast Cancer Resistance Protein ◽

Growth Factor Receptor ◽

Drug Efflux ◽

Cancer Resistance ◽

Mechanism Of Resistance ◽

Resistance Protein ◽

Receptor Inhibitor

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