Petalonia binghamiae Extract and Its Constituent Fucoxanthin Ameliorate High-Fat Diet-Induced Obesity by Activating AMP-Activated Protein Kinase

2012 ◽  
Vol 60 (13) ◽  
pp. 3389-3395 ◽  
Author(s):  
Seong-Il Kang ◽  
Hye-Sun Shin ◽  
Hyo-Min Kim ◽  
Seon-A Yoon ◽  
Seung-Woo Kang ◽  
...  
Keyword(s):  
Protein Kinase ◽  
High Fat Diet ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Amp Activated Protein Kinase ◽  
Petalonia Binghamiae

Emodin Protects against High-Fat Diet-Induced Obesity via Regulation of AMP-Activated Protein Kinase Pathways in White Adipose Tissue

Planta Medica ◽  
2012 ◽  
Vol 78 (10) ◽  
pp. 943-950 ◽  
Author(s):  
Thing-Fong Tzeng ◽  
Hung-Jen Lu ◽  
Shorong-Shii Liou ◽  
Chia Chang ◽  
I-Min Liu
Keyword(s):  
Adipose Tissue ◽  
Protein Kinase ◽  
White Adipose Tissue ◽  
High Fat Diet ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Amp Activated Protein Kinase

scholarly journals Dietary Silk Peptide Prevents High-Fat Diet-Induced Obesity and Promotes Adipose Browning by Activating AMP-Activated Protein Kinase in Mice

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 201 ◽  
Author(s):  
Kippeum Lee ◽  
Heegu Jin ◽  
Sungwoo Chei ◽  
Jeong-Yong Lee ◽  
Hyun-Ji Oh ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Protein Kinase ◽  
High Fat Diet ◽  
Ex Vivo ◽  
Uncoupling Protein ◽  
Acid Oxidation ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Silk Peptide ◽  
Amp Activated Protein Kinase

Obesity is associated with metabolic syndrome and other chronic diseases, and is caused when the energy intake is greater than the energy expenditure. We aimed to determine the mechanism whereby acid-hydrolyzed silk peptide (SP) prevents high-fat diet-induced obesity, and whether it induces browning and fatty acid oxidation (FAO) in white adipose tissue (WAT), using in vivo and ex vivo approaches. We determined the effects of dietary SP in high-fat diet-fed obese mice. The expression of adipose tissue-specific genes was quantified by western blotting, qRT-PCR, and immunofluorescence analysis. We also investigated whether SP directly induces browning in primarily subcutaneous WAT-derived adipocytes. Our findings demonstrate that SP has a browning effect in WAT by upregulating AMP-activated Protein Kinase (AMPK) phosphorylation and uncoupling protein 1 (UCP1) expression. SP also suppresses adipogenesis and promotes FAO, implying that it may have potential as an anti-obesity drug.

scholarly journals Cordycepin Prevents Hyperlipidemia in Hamsters Fed a High-Fat Diet via Activation of AMP-Activated Protein Kinase

2010 ◽  
Vol 113 (4) ◽  
pp. 395-403 ◽  
Author(s):  
Peng Guo ◽  
Qu Kai ◽  
Jian Gao ◽  
Ze-qin Lian ◽  
Chong-ming Wu ◽  
...  
Keyword(s):  
Protein Kinase ◽  
High Fat Diet ◽  
High Fat ◽  
Amp Activated Protein Kinase
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