Functional Comparison of Esterified and Free Forms of Conjugated Linoleic Acid in High-Fat-Diet-Induced Obese C57BL/6J Mice

2010 ◽  
Vol 58 (21) ◽  
pp. 11441-11447 ◽  
Author(s):  
Jun Ho Kim ◽  
Jeong Hoon Pan ◽  
Hui Gyu Park ◽  
Ho Geun Yoon ◽  
O-Jun Kwon ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
High Fat Diet ◽  
High Fat

scholarly journals Addition of conjugated linoleic acid in whole milk improves lipid profile in high fat diet induced hypercholesterolemia of rats

2016 ◽  
Vol 48 (04) ◽  
pp. 185-192
Author(s):  
Arta Farmawati ◽  
Rio Jati Kusuma ◽  
Bayu Sigha Iswara ◽  
. Wulandari ◽  
Kurniati Dwi Utami ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Lipid Profile ◽  
Conjugated Linoleic Acid ◽  
High Fat Diet ◽  
High Fat ◽  
Whole Milk

Conjugated linoleic acid and phytosterols counteract obesity induced by high-fat diet

2013 ◽  
Vol 51 (1) ◽  
pp. 429-435 ◽  
Author(s):  
Cibele Priscila Busch Furlan ◽  
Anne y Castro Marques ◽  
Rafaela da Silva Marineli ◽  
Mário Roberto Maróstica
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
High Fat Diet ◽  
High Fat

scholarly journals Co-Administration of Conjugated Linoleic Acid and Rosiglitazone Increases Atherogenic Co-Efficient and Alters Isoprenaline-Induced Vasodilatation in Rats Fed High Fat Diet

2018 ◽  
pp. 729-740
Author(s):  
B. K. CHAI ◽  
Y. S. LAU ◽  
B. J. LOONG ◽  
M. M. RAIS ◽  
K. N. TING ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
High Fat Diet ◽  
Normal Diet ◽  
High Density Lipoproteins ◽  
Oral Glucose ◽  
Peroxisome Proliferator ◽  
Sprague Dawley ◽  
High Fat

The cis(c)-9, trans(t)-11 (c9,t11) and t10,c12 isomers of conjugated linoleic acid (CLA) have been reported as agonists of peroxisome proliferator-activated receptor (PPAR) and beneficial in lipidemia and glycemia. However, it is unclear whether CLA isomers enhance or antagonize effects of conventional drugs targeting PPAR. Male Sprague-Dawley rats were fed high fat diet (HFD) for 8 weeks and treated without or with CLA, rosiglitazone or both for 4 weeks. Oral glucose tolerance and surrogate markers of insulin resistance were not significantly different for all treatments compared to untreated normal diet (ND) or HFD group, except lipoprotein levels. The combination of CLA and rosiglitazone had suppressed levels of low and high density lipoproteins (46 % and 25 %, respectively), compared to HFD-alone. Conversely, the atherogenic co-efficient of the animals received HFD or HFD+rosiglitazone+CLA was 2-folds higher than ND, HFD+rosiglitazone or HFD+CLA. Isolated aortic rings from the combined CLA and rosiglitazone treated animals were less sensitive to isoprenaline-induced relaxation among endothelium-denuded aortas with a decreased efficacy and potency (Rmax=53±4.7 %; pEC50=6±0.2) compared to endothelium-intact aortas (Rmax=100±9.9 %; pEC50=7±0.2). Our findings illustrate that the combination of CLA and rosiglitazone precede the atherogenic state with impaired endothelium-independent vasodilatation before the onset of HFD-induced insulin resistance.

Mixed conjugated linoleic acid sex‐dependently reverses high‐fat diet‐induced insulin resistance via the gut‐adipose axis

2021 ◽  
Vol 35 (4) ◽  
Author(s):  
Haoyu Li ◽  
Pan Zhuang ◽  
Yu Zhang ◽  
Qiyang Shou ◽  
Yanhua Lu ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
High Fat Diet ◽  
High Fat

Conjugated linoleic acid and chromium lower body weight and visceral fat mass in high-fat-diet-fed mice

Lipids ◽  
2006 ◽  
Vol 41 (5) ◽  
pp. 437-444 ◽  
Author(s):  
Arunabh Bhattacharya ◽  
M. Mizanur Rahman ◽  
Roger McCarter ◽  
Marianne O'Shea ◽  
Gabriel Fernandes
Keyword(s):  
Body Weight ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Fat Mass ◽  
Visceral Fat ◽  
High Fat Diet ◽  
Lower Body ◽  
High Fat ◽  
Lower Body Weight

scholarly journals Dietary conjugated linoleic acid reshapes high fat diet‐induced microbiota and reduces its immunogenicity

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Vanessa A Leone ◽  
Yunwei Wang ◽  
Suzanne Devkota ◽  
Mark W Musch ◽  
Dionysios Antonopoulos ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
High Fat Diet ◽  
High Fat ◽  
Dietary Conjugated Linoleic Acid
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