Development of a Stable Isotope Dilution Analysis with Liquid Chromatography−Tandem Mass Spectrometry Detection for the Quantitative Analysis of Di- and Trihydroxybenzenes in Foods and Model Systems

2006 ◽  
Vol 54 (16) ◽  
pp. 5755-5762 ◽  
Author(s):  
Roman Lang ◽  
Christoph Mueller ◽  
Thomas Hofmann
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Model Systems ◽  
Isotope Dilution Analysis ◽  
Tandem Mass ◽  
Mass Spectrometry Detection ◽  
Stable Isotope Dilution Analysis ◽  
Stable Isotope Dilution ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

A sensitive method to determine melatonin in saliva by automated online in-tube solid-phase microextraction coupled with stable isotope-dilution liquid chromatography-tandem mass spectrometry

2017 ◽  
Vol 9 (21) ◽  
pp. 3134-3140 ◽  
Author(s):  
Atsushi Ishizaki ◽  
Akiko Uemura ◽  
Hiroyuki Kataoka
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Stable Isotope ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Tandem Mass ◽  
Stable Isotope Dilution ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Sensitive Method

Melatonin (MLT) plays important roles in regulating the sleep-wake cycle, and has many beneficial effects on health. A simple, rapid, and sensitive method was developed for the determination of MLT in human saliva by automated online in-tube solid-phase microextraction coupled with stable isotope-dilution liquid chromatography-tandem mass spectrometry.

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