Water-soluble thiazolidines formed in a cysteamine-D-glucose browning model system

1981 ◽  
Vol 29 (2) ◽  
pp. 378-380 ◽  
Author(s):  
Kazunori Kitamura ◽  
Cheng-I Wei ◽  
Takayuki Shibamoto
Keyword(s):  
Model System ◽  
Water Soluble

Photocatalytic hydrogen production from a simple water-soluble [FeFe]-hydrogenase model system

2012 ◽  
Vol 48 (65) ◽  
pp. 8081 ◽  
Author(s):  
Wei-Ning Cao ◽  
Feng Wang ◽  
Hong-Yan Wang ◽  
Bin Chen ◽  
Ke Feng ◽  
...  
Keyword(s):  
Hydrogen Production ◽  
Model System ◽  
Water Soluble ◽  
Photocatalytic Hydrogen Production

scholarly journals Quantification of the hydrophobic effect using water-soluble super aryl-extended calix[4]pyrroles

2019 ◽  
Vol 6 (11) ◽  
pp. 1738-1748 ◽  
Author(s):  
Luis Escobar ◽  
Pablo Ballester
Keyword(s):  
Hydrophobic Effect ◽  
Model System ◽  
Water Soluble

We report the quantification of the hydrophobic effect using a model system based on water-soluble super aryl-extended calix[4]pyrrole receptors and a series of pyridyl N-oxide derivatives, bearing a non-polar para-substituent, as guests.

Impact of Multi-Walled Carbon Nanotubes on Aquatic Species

2008 ◽  
Vol 8 (7) ◽  
pp. 3603-3609 ◽  
Author(s):  
P. V. Asharani ◽  
N. G. B. Serina ◽  
M. H. Nurmawati ◽  
Y. L. Wu ◽  
Z. Gong ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Zebrafish Embryo ◽  
Model System ◽  
Water Soluble ◽  
Observable Effect ◽  
Teratogenic Effects ◽  
Effect Concentration ◽  
Multi Walled Carbon Nanotubes ◽  
High Concentrations ◽  
Walled Carbon Nanotubes

To understand the environmental impacts of carbon nanotubes (CNTs), the toxicity study was carried out with water-soluble multi-walled carbon nanotubes (MWCNTs) using zebrafish (Danio rerio) as a model system. Zebrafish embryos were treated with different concentrations of MWCNTs. Teratogenic effects were evaluated through changes in embryonic development after 24 hours post-fertilization (hpf), 48 hpf and 72 hpf. No observable effect concentration (NOEC) was at 40 μg/mL. Lowest effect concentration (LOEC) of MWCNTs which caused significant phenotypic defects in zebrafish embryo was 60 μg/mL. At concentration above 60 μg/mL, slimy mucus like coating was observed around the embryo. At high concentrations, MWCNTs was found to be involved in the apoptosis, delayed hatching and formation of abnormal spinal chords. Thus, the toxicity of multi-walled carbon nanotubes is concentration dependent.

Generation of Superoxide in a Water-Soluble Model System with FeTMPyP

2005 ◽  
Vol 78 (4) ◽  
pp. 703-709
Author(s):  
Taku Nakano ◽  
Kanae Ohto ◽  
Fumito Okafuji ◽  
Yoshihiro Mori ◽  
Hiroko Kakuda ◽  
...  
Keyword(s):  
Model System ◽  
Water Soluble ◽  
Soluble Model

Peroxidase-catalyzed conjugation of [4-14C] estradiol with albumin and thiols

1970 ◽  
Vol 48 (11) ◽  
pp. 1192-1198 ◽  
Author(s):  
P. H. Jellinck ◽  
Rosemarie Fletcher
Keyword(s):  
Horseradish Peroxidase ◽  
Rat Liver ◽  
Liver Microsomes ◽  
Model System ◽  
Water Soluble ◽  
Rat Liver Microsomes ◽  
Two Systems

The mechanism of conjugation of estradiol with either albumin or various thiols in the presence of horseradish peroxidase was studied and these two systems were shown to differ in a number of ways. With albumin, the reaction was slow, required Mn2+, and was inhibited by catalase but not iodoacetamide. In contrast, the reaction with thiols was rapid, did not require Mn2+, and was relatively insensitive to catalase. The yield of conjugates with different thiols and the effect of various inhibitors were also determined. The nature of the water-soluble steroid conjugate was investigated and the product obtained with glutathione shown to differ from that formed by rat liver microsomes. The possible extension of this model system to the situation existing in estrogen-stimulated uteri is discussed.

scholarly journals Amphotericin B protects cis-parinaric acid against peroxyl radical-induced oxidation: amphotericin B as an antioxidant.

1997 ◽  
Vol 41 (4) ◽  
pp. 743-747 ◽  
Author(s):  
K Osaka ◽  
V B Ritov ◽  
J F Bernardo ◽  
R A Branch ◽  
V E Kagan
Keyword(s):  
Amphotericin B ◽  
Antioxidant Properties ◽  
Model System ◽  
Antioxidant Effect ◽  
Water Soluble ◽  
Peroxyl Radicals ◽  
Target Cells ◽  
Prooxidant Effect ◽  
Parinaric Acid ◽  
Azo Initiator

The antifungal effects of amphotericin B are believed to be due to two possibly interrelated mechanisms: an increase in permeation by binding to sterols in cellular membranes and a prooxidant effect causing oxidative damage in target cells. However, the seven conjugated double bonds in amphotericin B raise the possibility that it could be highly susceptible to autoxidation, causing an antioxidant effect. In the present study, we investigated the prooxidant and antioxidant properties of amphotericin B in a model system in which oxidation of a reporter molecule, cis-parinaric acid, was induced by azo initiators of peroxyl radicals. Since interactions of amphotericin B with sterols are essential for its pharmacological and toxic actions, we also studied the effects of cholesterol on the prooxidant and antioxidant properties of amphotericin B. Amphotericin B caused a noncollisional quenching of a characteristic fluorescence of cholesteryl cis-parinarate integrated in liposomes, suggesting the formation of amphotericin B-cholesteryl cis-parinarate complex. This effect of amphotericin B was ablated by increasing concentrations of cholesterol. We found that amphotericin B inhibited oxidation of cis-parinaric acid complexed with human serum albumin [using a water-soluble azo initiator, 2,2'-azobis(2aminopropane)dihydrochloride] and in liposomes [using a lipid-soluble azo initiator, 2,2'-azobis(2,4-dimethylvaleronitrile)]. The inhibitory effect of amphotericin B on 2,2'-azobis(2,4-dimethylvaleronitrile)-induced peroxidation of cis-parinaric acid in liposomes was also diminished by cholesterol. The antioxidant effect of amphotericin B in this model system suggests that amphotericin B does not exert its pharmacological and toxicological responses through a prooxidant effect to cause damage in target cells.

scholarly journals A water-soluble supramolecular complex that mimics the heme/copper hetero-binuclear site of cytochrome c oxidase

2018 ◽  
Vol 9 (7) ◽  
pp. 1989-1995 ◽  
Author(s):  
Hiroaki Kitagishi ◽  
Daiki Shimoji ◽  
Takehiro Ohta ◽  
Ryo Kamiya ◽  
Yasuhiro Kudo ◽  
...  
Keyword(s):  
Cytochrome C ◽  
Cytochrome C Oxidase ◽  
Model System ◽  
Supramolecular Complex ◽  
Water Soluble

The O2 adduct of an aqueous synthetic heme/copper model system built on a porphyrin/cyclodextrin supramolecular complex has been characterized.

Sign in / Sign up

Export Citation Format

Share Document