Optimization for selective fractionation of bovine blood plasma proteins using poly(ethylene glycol)

1987 ◽  
Vol 35 (6) ◽  
pp. 958-962 ◽  
Author(s):  
Young Zoon Lee ◽  
Tetsuo Aishima ◽  
Shuryo Nakai ◽  
Jeong S. Sim
Biomaterials ◽  
2003 ◽  
Vol 24 (27) ◽  
pp. 4949-4958 ◽  
Author(s):  
S. Tosatti ◽  
S.M.De Paul ◽  
A. Askendal ◽  
S. VandeVondele ◽  
J.A. Hubbell ◽  
...  

Nanomedicine ◽  
2021 ◽  
Author(s):  
Xueping Liu ◽  
Hong Luo ◽  
Longxing Niu ◽  
Yanfei Feng ◽  
Peng Pan ◽  
...  

Aim: To obtain a gene carrier that can effectively deliver loaded therapeutic genes to tumor cells, avoid toxic effects on normal cells and reduce nonspecific adsorption of plasma proteins. Methods: The conjugate of poly(ethylene glycol) (PEG) and MMP2SSP (PEG-MMP2SSP) was covalently coupled to cationized Antheraea pernyi silk fibroin (CASF) through disulfide bond exchange reaction to obtain a PEG-MMP2SSP-modified CASF (CASFMP). Results: The PEG chains were effectively cleaved from the CASFMP by MMP2. CASFMP/pDNA complexes inhibited human fibrosarcoma cell proliferation, and its cytotoxicity to human normal embryonic kidney cells was significantly lower than that of poly(ethylenimine)/pDNA after coculturing with cells for 24 h. Conclusion: CASFMP is a promising compound for use in gene therapy.


Langmuir ◽  
2013 ◽  
Vol 29 (10) ◽  
pp. 3388-3397 ◽  
Author(s):  
Tomáš Riedel ◽  
Zuzana Riedelová-Reicheltová ◽  
Pavel Májek ◽  
César Rodriguez-Emmenegger ◽  
Milan Houska ◽  
...  

2019 ◽  
Vol 10 (10) ◽  
Author(s):  
Anton Bonartsev ◽  
Vera Voinova ◽  
Elizaveta Akoulina ◽  
Andrey Dudun ◽  
Irina Zharkova ◽  
...  

2007 ◽  
Vol 32 (5) ◽  
pp. 431-446 ◽  
Author(s):  
Tahar Bartil ◽  
Mahmoud Bounekhel ◽  
Cedric Calberg ◽  
Robert Jerome

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