Partition Coefficients of Organic Solutes between Supercritical Carbon Dioxide and Water:  Experimental Measurements and Empirical Correlations

2004 ◽  
Vol 49 (4) ◽  
pp. 768-778 ◽  
Author(s):  
Michael T. Timko ◽  
Benjamin F. Nicholson ◽  
Jeffrey I. Steinfeld ◽  
Kenneth A. Smith ◽  
Jefferson W. Tester
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Partition Coefficients ◽  
Experimental Measurements ◽  
Organic Solutes ◽  
Empirical Correlations ◽  
Supercritical Carbon

scholarly journals Solubility and Partition Coefficients of Fish Oil Esters in Supercritical Carbon Dioxide.

1994 ◽  
Vol 27 (1) ◽  
pp. 132-134 ◽  
Author(s):  
Arne Staby ◽  
Christina Borch-Jensen ◽  
Jørgen <!--Jolgen--> Mollerup
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Fish Oil ◽  
Partition Coefficients ◽  
Supercritical Carbon

Solubility of the Ketoconazole (an Antifungal Drug) in Supercritical Carbon Dioxide and Menthol as a Cosolvent (Ternary System): Experimental Data and Empirical Correlations

2021 ◽  
Author(s):  
Gholamhossein Sodeifian ◽  
Seyed Ali Sajadian ◽  
Fariba Razmimanesh ◽  
Seyed Mojtaba Hazaveie
Keyword(s):  
Experimental Data ◽  
Carbon Dioxide ◽  
Binary System ◽  
Supercritical Carbon Dioxide ◽  
Ternary System ◽  
Drug Solubility ◽  
Analysis Method ◽  
Empirical Correlations ◽  
Semiempirical Models ◽  
Supercritical Carbon

Abstract One of the main steps in choosing the drug nanoparticle production processes by supercritical carbon dioxide (SC-CO2) is determining the solubility of the solid solute. For this purpose, the solubility of Ketoconazole (KTZ) in the SC-CO2, binary system, as well as in the SC-CO2-menthol (cosolvent), ternary system, was measured at 308–338 K and 12–30 MPa using the static analysis method. The KTZ solubility in the SC-CO2 ranged between 1.70×10− 6 and 8.02×10− 4, while drug solubility in the SC-CO2 with cosolvent varied from 2.7×10− 5 to 1.96×10− 4. This difference indicated the significant effect of menthol cosolvent on KTZ solubility in the SC-CO2. Moreover, KTZ solubilities in the two systems were correlated by several empirical and semiempirical models. Among them, Sodeifian et al., Bian et al., MST, and Bartle et al. models can more accurately correlate experimental data for the binary system than other used models. Also, the Sodeifian and Sajadian model well fitted the solubility data of the ternary system with AARD,%= 6.45, Radj= 0.995.

Supercritical carbon dioxide-soil partition coefficients

1995 ◽  
Vol 8 (2) ◽  
pp. 149-155 ◽  
Author(s):  
Douglas J. Gray ◽  
Richard G. Zytner ◽  
Warren H. Stiver
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Partition Coefficients ◽  
Supercritical Carbon

scholarly journals Characterization of Non-Equilibrium Condensation of Supercritical Carbon Dioxide in a de Laval Nozzle

2017 ◽  
Author(s):  
Claudio Lettieri ◽  
Derek Paxson ◽  
Zoltan Spakovszky ◽  
Peter Bryanston-Cross
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Critical Point ◽  
Laval Nozzle ◽  
Experimental Measurements ◽  
Fluid Properties ◽  
Inlet Conditions ◽  
Direct Extrapolation ◽  
Supercritical Carbon

On a ten-year timescale, Carbon Capture and Storage could significantly reduce carbon dioxide (CO2) emissions. One of the major limitations of this technology is the energy penalty for the compression of CO2 to supercritical conditions, which can require up to 15% of the plant’s gross power output. To reduce the power requirements supercritical carbon dioxide compressors must operate at reduced temperatures and near saturation where phase change effects are important. Non-equilibrium condensation can occur in the high-speed flow at the leading edge of the compressor, causing performance and stability issues. The characterization of the fluid at these conditions is vital to enable advanced compressor designs at enhanced efficiency levels but the analysis is challenging due to the lack of data on the metastable fluid properties. In this paper we assess the metastable behavior and nucleation characteristics of high-pressure subcooled carbon dioxide during the expansion in a Laval nozzle. The assessment is conducted with numerical calculations, supported and corroborated by experimental measurements. The Wilson line is determined via optical measurements in the range of 41 and 82 bar and near the critical point. The state of the metastable fluid is fully characterized through pressure and density measurements, with the latter obtained in a first of its kind laser interferometry set up. In a systematic analysis the inlet conditions of the nozzle are moved close to the critical point to allow for large gradients in fluid properties and reduced margin to condensation. The results of calculations using a direct extrapolation of the Span and Wagner equation of state model are compared with the experimental measurements. The analysis suggests that the direct extrapolation using the Span and Wagner model yields results within 2% of the experimental data, with improved accuracy at conditions away from the critical point. The results are applied in a pre-production supercritical carbon dioxide compressor and are used to define inlet conditions at reduced temperature but free of condensation. Full-scale compressor experiments demonstrate that the new inlet conditions can reduce the shaft power input by 16%.

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