Catalytic Asymmetric Construction of Halogenated Stereogenic Carbon Centers by Direct Vinylogous Mannich-Type Reaction

2018 ◽  
Vol 140 (45) ◽  
pp. 15170-15175 ◽  
Author(s):  
Feng Zhong ◽  
Wen-Jun Yue ◽  
Hai-Jun Zhang ◽  
Cheng-Yuan Zhang ◽  
Liang Yin
Keyword(s):  
Type Reaction ◽  
Carbon Centers ◽  
Catalytic Asymmetric

Catalytic Asymmetric Three-Component Mannich-Type Reaction of Alkenyl Trichloroacetates

2009 ◽  
Vol 11 (22) ◽  
pp. 5310-5313 ◽  
Author(s):  
Atsuto Izumiseki ◽  
Kazuhiro Yoshida ◽  
Akira Yanagisawa
Keyword(s):  
Type Reaction ◽  
Catalytic Asymmetric

A Catalytic Asymmetric Strecker-Type Reaction: Interesting Reactivity Difference between TMSCN and HCN

2000 ◽  
Vol 112 (9) ◽  
pp. 1716-1718 ◽  
Author(s):  
Masahiro Takamura ◽  
Yoshitaka Hamashima ◽  
Hiroyuki Usuda ◽  
Motomu Kanai ◽  
Masakatsu Shibasaki
Keyword(s):  
Type Reaction ◽  
Catalytic Asymmetric

scholarly journals Chiral ammonium betaine-catalyzed asymmetric Mannich-type reaction of oxindoles

2016 ◽  
Vol 12 ◽  
pp. 2099-2103 ◽  
Author(s):  
Masahiro Torii ◽  
Kohsuke Kato ◽  
Daisuke Uraguchi ◽  
Takashi Ooi
Keyword(s):  
High Fidelity ◽  
Catalytic Method ◽  
Type Reaction ◽  
Carbon Centers ◽  
Axially Chiral

A highly diastereo- and enantioselective Mannich-type reaction of 3-aryloxindoles with N-Boc aldimines was achieved under the catalysis of axially chiral ammonium betaines. This catalytic method provides a new tool for the construction of consecutive quaternary and tertiary stereogenic carbon centers on biologically intriguing molecular frameworks with high fidelity.

scholarly journals Direct Catalytic Asymmetric Mannich-Type Reaction of an α-CF3 Amide to Isatin Imines

Synlett ◽  
2018 ◽  
Vol 30 (04) ◽  
pp. 488-492 ◽  
Author(s):  
Jin-Sheng Yu ◽  
Hidetoshi Noda ◽  
Naoya Kumagai ◽  
Masakatsu Shibasaki
Keyword(s):  
Lewis Acid ◽  
Tertiary Amine ◽  
Chiral Center ◽  
Chiral Catalyst ◽  
Type Reaction ◽  
One Step ◽  
Catalytic Asymmetric ◽  
Chiral Bisphosphine Ligand

An α-CF3 amide underwent direct asymmetric Mannich-type reaction to isatin imines in the presence of a chiral catalyst comprising a soft Lewis acid Cu(I), a chiral bisphosphine ligand, and Barton’s base. The Mannich adduct was converted in one step into a unique tricycle bearing a trifluoromethylated chiral center and an α-tertiary amine moiety.

Direct Catalytic Asymmetric Mannich-Type Reaction of α- and β-Fluorinated Amides

2015 ◽  
Vol 137 (50) ◽  
pp. 15929-15939 ◽  
Author(s):  
Lennart Brewitz ◽  
Fernando Arteaga Arteaga ◽  
Liang Yin ◽  
Kaliyamoorthy Alagiri ◽  
Naoya Kumagai ◽  
...  
Keyword(s):  
Type Reaction ◽  
Catalytic Asymmetric

ChemInform Abstract: A Catalytic Asymmetric Ugi-Type Reaction with Acyclic Azomethine Imines.

ChemInform ◽  
2013 ◽  
Vol 44 (1) ◽  
pp. no-no
Author(s):  
Takuya Hashimoto ◽  
Hidenori Kimura ◽  
Yu Kawamata ◽  
Keiji Maruoka
Keyword(s):  
Type Reaction ◽  
Azomethine Imines ◽  
Catalytic Asymmetric
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