Regio- and Enantioselective Rhodium-Catalyzed Allylic Alkylation of Racemic Allylic Alcohols with 1,3-Diketones

2018 ◽  
Vol 140 (24) ◽  
pp. 7737-7742 ◽  
Author(s):  
Sheng-Biao Tang ◽  
Xiao Zhang ◽  
Hang-Fei Tu ◽  
Shu-Li You
Keyword(s):  
Allylic Alcohols ◽  
Allylic Alkylation

Palladium-Catalyzed Allylic Alkylation of Simple Ketones with Allylic Alcohols and Its Mechanistic Study

2014 ◽  
Vol 126 (26) ◽  
pp. 6894-6898 ◽  
Author(s):  
Xiaohong Huo ◽  
Guoqiang Yang ◽  
Delong Liu ◽  
Yangang Liu ◽  
Ilya D. Gridnev ◽  
...  
Keyword(s):  
Mechanistic Study ◽  
Allylic Alcohols ◽  
Allylic Alkylation ◽  
Palladium Catalyzed

Iodine-catalyzed allylic alkylation of sulfonamides and carbamates with allylic alcohols at room temperature

2008 ◽  
Vol 49 (16) ◽  
pp. 2620-2624 ◽  
Author(s):  
Wenhan Wu ◽  
Weidong Rao ◽  
Ya Qin Er ◽  
Joanna Kejun Loh ◽  
Chai Yun Poh ◽  
...  
Keyword(s):  
Room Temperature ◽  
Allylic Alcohols ◽  
Allylic Alkylation

scholarly journals Iridium-Catalyzed Asymmetric α-Allylic Alkylation of Amides using Vinyl Azide as Amide Enolate Surrogate

2020 ◽  
Author(s):  
Aditya Chakrabarty ◽  
Santanu Mukherjee
Keyword(s):  
Electronic Properties ◽  
Reaction Pathways ◽  
Allylic Alcohols ◽  
Allylic Alkylation ◽  
Atom Economy ◽  
Asymmetric Allylic Alkylation ◽  
Vinyl Azides ◽  
Alkylation Reactions ◽  
First Time

Among the unstabilized enolates used as nucleophile in iridium-catalyzed asymmetric allylic alkylation reactions, amide enolates are least explored. Vinyl azides are now employed as amide enolate surrogate for the first time in Ir-catalyzed asymmetric allylic alkylation with branched allylic alcohols as the allylic electrophile. Competing reaction pathways are suppressed through systematic tuning of steric and electronic properties of vinyl azide to effect α-allylic alkylation of secondary acetamides with high atom-economy, exclusive branched selectivity and moderate to excellent enantioselectivity.<br>

ChemInform Abstract: Palladium-Catalyzed Allylic Alkylation of Simple Ketones with Allylic Alcohols and Its Mechanistic Study.

ChemInform ◽  
2015 ◽  
Vol 46 (1) ◽  
Author(s):  
Xiaohong Huo ◽  
Guoqiang Yang ◽  
Delong Liu ◽  
Yangang Liu ◽  
Ilya D. Gridnev ◽  
...  
Keyword(s):  
Mechanistic Study ◽  
Allylic Alcohols ◽  
Allylic Alkylation ◽  
Palladium Catalyzed
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