Catalyst-Controlled Diastereoselective Synthesis of Cyclic Amines via C-H Functionalization

2017 ◽  
Author(s):  
Sailu Munnuri ◽  
Adeniyi Michael Adebesin ◽  
Mahesh P Paudyal ◽  
Muhammed Yousufuddin ◽  
Alfonso Dalipe ◽  
...  
Keyword(s):  
Diastereoselective Synthesis ◽  
Cyclic Amines

ChemInform Abstract: Furanyl Cyclic Amines: A Diastereoselective Synthesis of 2,6-syn-Disubstituted Piperidines under Thermodynamic Control.

ChemInform ◽  
2012 ◽  
Vol 43 (33) ◽  
pp. no-no
Author(s):  
Matthew O'Brien ◽  
Andrew Leach ◽  
Roly J. Armstrong ◽  
Keting Chong ◽  
Ross Sheridan
Keyword(s):  
Diastereoselective Synthesis ◽  
Thermodynamic Control ◽  
Cyclic Amines

Furanyl cyclic amines: a diastereoselective synthesis of 2,6-syn-disubstituted piperidines under thermodynamic control

2012 ◽  
Vol 10 (12) ◽  
pp. 2392 ◽  
Author(s):  
Matthew O'Brien ◽  
Andrew Leach ◽  
Roly J. Armstrong ◽  
Keting Chong ◽  
Ross Sheridan
Keyword(s):  
Diastereoselective Synthesis ◽  
Thermodynamic Control ◽  
Cyclic Amines

Naturally Occurring Organic Acid-catalyzed Facile Diastereoselective Synthesis of Biologically Active (E)-3-(arylimino)indolin-2-one Derivatives in Water at Room Temperature

2019 ◽  
Vol 23 (16) ◽  
pp. 1778-1788 ◽  
Author(s):  
Gurpreet Kaur ◽  
Arvind Singh ◽  
Kiran Bala ◽  
Mamta Devi ◽  
Anjana Kumari ◽  
...  
Keyword(s):  
Room Temperature ◽  
Biologically Active ◽  
Environmentally Benign ◽  
Diastereoselective Synthesis ◽  
Substituted Anilines ◽  
Reaction Conditions ◽  
Naturally Occurring ◽  
Acid Catalyzed ◽  
Reaction Media ◽  
Column Chromatographic

A simple, straightforward and efficient method has been developed for the synthesis of (E)-3-(arylimino)indolin-2-one derivatives and (E)-2-((4-methoxyphenyl)imino)- acenaphthylen-1(2H)-one. The synthesis of these biologically-significant scaffolds was achieved from the reactions of various substituted anilines and isatins or acenaphthaquinone, respectively, using commercially available, environmentally benign and naturally occurring organic acids such as mandelic acid or itaconic acid as catalyst in aqueous medium at room temperature. Mild reaction conditions, energy efficiency, good to excellent yields, environmentally benign conditions, easy isolation of products, no need of column chromatographic separation and the reusability of reaction media are some of the significant features of the present protocol.

Diastereoselective Synthesis of Novel Optically Active Five Membered O- and N-heterocyclic Compounds

2012 ◽  
Vol 9 (2) ◽  
pp. 81-88 ◽  
Author(s):  
Ervin Kovacs ◽  
Ferenc Farkas ◽  
Angelika Thurner ◽  
Aron Szollosy ◽  
Ferenc Faigl
Keyword(s):  
Heterocyclic Compounds ◽  
Optically Active ◽  
Diastereoselective Synthesis
Sign in / Sign up

Export Citation Format

Share Document