Correction to “Generation of Chiral Phosphonium Dialkyl Phosphite as a Highly Reactive P-Nucleophile: Application to Asymmetric Hydrophosphonylation of Aldehydes”

2017 ◽  
Vol 139 (8) ◽  
pp. 3299-3299 ◽  
Author(s):  
Daisuke Uraguchi ◽  
Takaki Ito ◽  
Takashi Ooi
Keyword(s):  
Dialkyl Phosphite

ChemInform Abstract: A Novel Reagent, Dialkyl Phosphite, for Peptide Synthesis.

ChemInform ◽  
2010 ◽  
Vol 22 (40) ◽  
pp. no-no
Author(s):  
Y.-F. ZHAO ◽  
D.-Q. ZHANG ◽  
C.-B. XUE
Keyword(s):  
Peptide Synthesis ◽  
Dialkyl Phosphite

Magnesium Perchlorate Catalyzed Phospha-Michael Addition of Dialkyl Phosphite to Chalcone

2018 ◽  
Vol 15 (7) ◽  
pp. 1020-1023 ◽  
Author(s):  
Adarsh Sahu ◽  
Shweta Mishra ◽  
Asmita Gajbhiye ◽  
Ram Kishore Agrawal
Keyword(s):  
Bond Formation ◽  
Solvent Free ◽  
Diethyl Phosphite ◽  
Unsaturated Ketone ◽  
Dialkyl Phosphite ◽  
Magnesium Perchlorate ◽  
One Pot ◽  
Free Condition ◽  
Solvent Free Condition ◽  
Derivatives Of

Aim and Objective: Phosphonate possesses a broad range of applications ranging from agrochemistry to medicines. Because of the synthetic and biological importance of phosphonate, their chemistry has stimulated an increasing interest. Hence we developed an efficient and eco-friendly Mg(ClO4)2 catalyzed one pot, solvent free synthesis of phosphonate derivatives of chalcones. Materials and Methods: Magnesium perchlorate phosphonate derivatives of chalcones were synthesized. The reactions were executed at room temperature in the presence of Anhydrous Magnesium perchlorate Anhy. Mg(ClO4)2 under solvent free condition, affording high yield of the product. The cardinal significance of the method lies in its uncomplicated and eco- friendly experimental conditions. Results: The PMA method for P-C bond formation, using dialkyl phosphite with chalcone, was performed in the presence of Anhydrous Magnesium perchlorate under solvent free condition. Despite the solvent free condition, the methodology is efficient since it is required only in catalytic amount of Anhy. Mg(ClO4)2 in one pot reaction. Results demonstrated that the catalytic PMA of dimethyl phosphite, diethyl phosphite, diisopropyl phosphite and dibutyl phosphite with chalcone generates desired products with a percentage yield of 60-80%. Conclusion: We have developed a new efficient PMA method for P-C bond formation, using dialkyl phosphite with α,β-unsaturated ketone i.e. chalcone. To the best of our knowledge, Anhy. Mg(ClO4)2 catalyzed phosphamicheal addition of dialkyl phosphite with chalcones was found to be a new and efficient method for various biological applications.

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