scholarly journals Total Synthesis of (+)-SCH 351448: Efficiency via Chemoselectivity and Redox-Economy Powered by Metal Catalysis

2016 ◽  
Vol 138 (26) ◽  
pp. 8088-8091 ◽  
Author(s):  
Gang Wang ◽  
Michael J. Krische
Keyword(s):  
Total Synthesis ◽  
Metal Catalysis ◽  
Sch 351448

Total Synthesis of (+)-SCH 351448

2004 ◽  
Vol 126 (9) ◽  
pp. 2680-2681 ◽  
Author(s):  
Eun Joo Kang ◽  
Eun Jin Cho ◽  
Young Eun Lee ◽  
Mi Kyung Ji ◽  
Dong Mok Shin ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Sch 351448

Total Synthesis of (+)-SCH 351448.

ChemInform ◽  
2004 ◽  
Vol 35 (30) ◽  
Author(s):  
Eun Joo Kang ◽  
Eun Jin Cho ◽  
Young Eun Lee ◽  
Mi Kyung Ji ◽  
Dong Mok Shin ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Sch 351448

Total Synthesis of Microbial Polyketides: (+)-SCH 351448

ChemInform ◽  
2006 ◽  
Vol 37 (45) ◽  
Author(s):  
Martin Hiersemann
Keyword(s):  
Total Synthesis ◽  
Sch 351448

Enantioselective Total Synthesis of (+)-SCH 351448

2006 ◽  
Vol 8 (13) ◽  
pp. 2887-2890 ◽  
Author(s):  
Michael T. Crimmins ◽  
Grace S. Vanier
Keyword(s):  
Total Synthesis ◽  
Enantioselective Total Synthesis ◽  
Sch 351448

scholarly journals Catalytic asymmetric synthesis of biologically important 3-hydroxyoxindoles: an update

2016 ◽  
Vol 12 ◽  
pp. 1000-1039 ◽  
Author(s):  
Bin Yu ◽  
Hui Xing ◽  
De-Quan Yu ◽  
Hong-Min Liu
Keyword(s):  
Clinical Trials ◽  
Natural Products ◽  
Drug Discovery ◽  
Total Synthesis ◽  
Asymmetric Synthesis ◽  
Biological Activities ◽  
Transition Metal Catalysis ◽  
Metal Catalysis ◽  
Catalytic Asymmetric Synthesis ◽  
Catalytic Asymmetric

Oxindole scaffolds are prevalent in natural products and have been recognized as privileged substructures in new drug discovery. Several oxindole-containing compounds have advanced into clinical trials for the treatment of different diseases. Among these compounds, enantioenriched 3-hydroxyoxindole scaffolds also exist in natural products and have proven to possess promising biological activities. A large number of catalytic asymmetric strategies toward the construction of 3-hydroxyoxindoles based on transition metal catalysis and organocatalysis have been reported in the last decades. Additionally, 3-hydroxyoxindoles as versatile precursors have also been used in the total synthesis of natural products and for constructing structurally novel scaffolds. In this review, we aim to provide an overview about the catalytic asymmetric synthesis of biologically important 3-substituted 3-hydroxyoxindoles and 3-hydroxyoxindole-based further transformations.

Flexible Total Synthesis of 11‐Deoxylandomycins and Their Non‐Natural Analogues by Way of Asymmetric Metal Catalysis

2019 ◽  
Vol 132 (6) ◽  
pp. 2369-2373
Author(s):  
Juyeol Lee ◽  
Jihun Kang ◽  
Sukhyun Lee ◽  
Young Ho Rhee
Keyword(s):  
Total Synthesis ◽  
Metal Catalysis ◽  
Natural Analogues
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