Cp*Co(III)-Catalyzed Enantioselective Hydroarylation of Unactivated Terminal Alkenes via C–H Activation

ANIPE-Cu Catalyst Enables Highly Enantioselective Markovnikov Hydroboration of α-Olefins

Synlett ◽

10.1055/s-1288-2990 ◽

2020 ◽

Author(s):

Shi-Liang Shi ◽

Yuan Cai

Keyword(s):

Petrochemical Industry ◽

Future Directions ◽

Asymmetric Hydroboration ◽

Terminal Alkenes ◽

Cu Catalyst

AbstractAsymmetric hydroboration of simple and unactivated terminal alkenes (α-olefins), feedstock chemicals derived from the petrochemical industry, has not been efficiently realized for past decades. Using a bulky ANIPE ligand, we achieved a rare example of highly enantioselective copper-catalyzed Markovnikov hydroboration of α-olefins. The chiral secondary alkylboronic ester products were obtained in moderate to good yields and regioselectivities with excellent enantioselectivities.1 Introduction2 Conditions Optimization3 Substrate Scope4 Application5 Mechanistic Discussion6 Conclusions and Future Directions

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Thioether-Facilitated Iridium-Catalyzed Hydrosilylation of Steric 1,1-Disubstituted Olefins

10.26434/chemrxiv.9859103.v1 ◽

2019 ◽

Author(s):

Shengtao Ding

Keyword(s):

Side Chains ◽

Feasible Method ◽

Iridium Catalysis ◽

Efficient Strategy ◽

Terminal Alkenes ◽

And Control ◽

Sulfur Containing ◽

Organosilicon Polymers

One facile and efficient strategy for the hydrosilylation of steric 1,1-disubstituted terminal alkenes is demonstrated. Investigations on substrate scope and control experiments revealed the necessity of thioether in promoting this process under a simple iridium catalysis system. This convenient and feasible method is expected to be useful in the synthesis of sulfur-containing organosilicon polymers with different side-chains.

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Rh(III) catalyzed allylic C-H amidation of unactivated alkenes with in situ generated iminoiodinanes

Chemical Communications ◽

10.1039/d1cc02283k ◽

2021 ◽

Author(s):

Masilamani Jeganmohan ◽

Pinki Sihag

Keyword(s):

Terminal Alkenes

A Rh(III) catalyzed allylic C H amidation of substituted alkenes with in situ generated iminoiodinanes is demonstrated. The present protocol is compatible with differently functionalized unactivated terminal alkenes and internal...

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Palladium-catalyzed 1,1-alkynylbromination of alkenes with alkynyl bromides

Chemical Science ◽

10.1039/d1sc02873a ◽

2021 ◽

Author(s):

Yusuke Ano ◽

Natsuki Kawai ◽

Naoto Chatani

Keyword(s):

Diverse Range ◽

Terminal Alkenes ◽

Palladium Catalyzed

The palladium-catalyzed 1,1-alkynylbromination of terminal alkenes with a silyl-protected alkynyl bromide is reported. The method tolerates a diverse range of alkenes including vinylarenes, acrylates, and even electronically unbiased alkene derivatives...

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Oxidative Alkylation/Alkynylation of Terminal Alkenes via Alkylaldehyde Decarbonylation and 1,2-Alkynyl Migration

Organic & Biomolecular Chemistry ◽

10.1039/d1ob00212k ◽

2021 ◽

Author(s):

Jiajia Zhang ◽

De Chen ◽

yiqun qin ◽

Wei Deng ◽

Yongyue luo ◽

...

Keyword(s):

Functional Group ◽

Quaternary Carbon ◽

Metal Free ◽

Terminal Alkenes ◽

Oxidative Alkylation

A metal-free oxidative alkene alkylation/alkynylation of 1,4-enyn-3-ols with alkylaldehydes has been achieved, which offers a general access to the challenging quaternary carbon-containing but-3-yn-1-ones. The method features with excellent functional group...

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