scholarly journals Hydration Layer of Only a Few Molecules Controls Lipid Mobility in Biomimetic Membranes

2021 ◽  
Author(s):  
Madhurima Chattopadhyay ◽  
Emilia Krok ◽  
Hanna Orlikowska ◽  
Petra Schwille ◽  
Henri G. Franquelim ◽  
...  
Keyword(s):  
Hydration Layer ◽  
Biomimetic Membranes ◽  
Lipid Mobility

scholarly journals Hydration layer of only few molecules controls lipid mobility in biomimetic membranes

2021 ◽  
Author(s):  
Madhurima Chattopadhyay ◽  
Emilia Krok ◽  
Hanna Orlikowska ◽  
Petra Schwille ◽  
Henri G. Franquelim ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Strong Dependence ◽  
Lateral Diffusion ◽  
Diffusion Activation Energy ◽  
Water Molecules ◽  
Hydration Layer ◽  
Lipid Molecule ◽  
Wide Range ◽  
Lipid Mobility ◽  
Lipid Diffusion

Self-assembly of biomembranes results from the intricate interactions between water and the lipids' hydrophilic head groups. Therefore, the lipid-water interplay strongly contributes to modulating membranes architecture, lipid diffusion, and chemical activity. Here, we introduce a new method of obtaining dehydrated, phase-separated, supported lipid bilayers (SLBs) solely by controlling the decrease of their environment's relative humidity. This facilitates the study of the structure and dynamics of SLBs over a wide range of hydration states. We show that the lipid domain structure of phase-separated SLBs is largely insensitive to the presence of the hydration layer. In stark contrast, lipid mobility is drastically affected by dehydration, showing a 6-fold decrease in lateral diffusion. At the same time, the diffusion activation energy increases approximately twofold for the dehydrated membrane. The obtained results, correlated with the hydration structure of a lipid molecule, revealed that about 6-7 water molecules directly hydrating the phosphocholine moiety play a pivotal role in modulating lipid diffusion. These findings could provide deeper insights into the fundamental reactions where local dehydration occurs, for instance during cell-cell fusion, and help us better understand the survivability of anhydrobiotic organisms. Finally, the strong dependence of lipid mobility on the number of hydrating water molecules opens up an application potential for SLBs as very precise, nanoscale hydration sensors.

Fabrication and Filtration Performance of Aquaporin Biomimetic Membranes for Water Treatment

2021 ◽  
pp. 1-18
Author(s):  
Angelo Beratto-Ramos ◽  
Jorge Dagnino-Leone ◽  
José Martínez-Oyanedel ◽  
Mario Aranda ◽  
Rodrigo Bórquez
Keyword(s):  
Water Treatment ◽  
Biomimetic Membranes ◽  
Filtration Performance

scholarly journals Specific uptake and interactions of peptide nucleic acid derivatives with biomimetic membranes

RSC Advances ◽  
2012 ◽  
Vol 2 (11) ◽  
pp. 4703 ◽  
Author(s):  
Tanmaya Joshi ◽  
Gilles Gasser ◽  
Lisandra L. Martin ◽  
Leone Spiccia
Keyword(s):  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Biomimetic Membranes ◽  
Specific Uptake

Assessment of the impact of nanoparticles on the activity of biomimetic membrane

2021 ◽  
Vol XXXVII (1) ◽  
pp. 89-100
Author(s):  
Dorota Kondej
Keyword(s):  
Occupational Safety ◽  
Biological Membranes ◽  
Structure And Function ◽  
Lipid Monolayer ◽  
Biomimetic Membranes ◽  
Safety And Health ◽  
Biomimetic Membrane ◽  
And Function ◽  
The Impact

This paper presents basic information on a structure and function of biological membranes. Types of biomimetic membranes modelling properties of biological membranes were introduced. The method of testing surface properties of a lipid monolayer, which is the basic type of biomimetic membranes, was described. The presented method makes it possible to evaluate the effect of nanoparticles on the surface activity of biomimetic membranes based on the determination of the surface index MA. This article discusses the problems of occupational safety and health, which are covered by health sciences and environmental engineering.

1.1 From Biological Membranes to Artificial Biomimetic Membranes and Systems

2017 ◽  
pp. 1-16
Author(s):  
Emma Piacentini ◽  
Rosalinda Mazzei ◽  
Enrico Drioli ◽  
Lidietta Giorno
Keyword(s):  
Biological Membranes ◽  
Biomimetic Membranes

Lasalocid and biomimetic membranes: insertion in Langmuir films of lipids

1994 ◽  
Vol 1193 (2) ◽  
pp. 287-292 ◽  
Author(s):  
Hans Hasmonay ◽  
Ambjörg Hochapfel ◽  
Claudine Betrencourt ◽  
Amar Tahir ◽  
Pierre Peretti
Keyword(s):  
Langmuir Films ◽  
Biomimetic Membranes

scholarly journals Hydration Dynamics and the Future of Small-Amplitude AFM Imaging in Air

Molecules ◽  
2021 ◽  
Vol 26 (23) ◽  
pp. 7083
Author(s):  
Sergio Santos ◽  
Tuza A. Olukan ◽  
Chia-Yun Lai ◽  
Matteo Chiesa
Keyword(s):  
High Resolution ◽  
Small Amplitude ◽  
Stable State ◽  
High Resolution Imaging ◽  
Hydration Layer ◽  
Afm Imaging ◽  
The Future ◽  
Resolution Imaging ◽  
Tip Radius ◽  
Hydration Dynamics

Here, we discuss the effects that the dynamics of the hydration layer and other variables, such as the tip radius, have on the availability of imaging regimes in dynamic AFM—including multifrequency AFM. Since small amplitudes are required for high-resolution imaging, we focus on these cases. It is possible to fully immerse a sharp tip under the hydration layer and image with amplitudes similar to or smaller than the height of the hydration layer, i.e., ~1 nm. When mica or HOPG surfaces are only cleaved, molecules adhere to their surfaces, and reaching a thermodynamically stable state for imaging might take hours. During these first hours, different possibilities for imaging emerge and change, implying that these conditions must be considered and reported when imaging.

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