scholarly journals Host–Guest Induced Peptide Folding with Sequence-Specific Structural Chirality

2021 ◽  
Author(s):  
David E. Clarke ◽  
Guanglu Wu ◽  
Ce Wu ◽  
Oren A. Scherman
Keyword(s):  
Peptide Folding

scholarly journals Does liquid–liquid phase separation drive peptide folding?

2021 ◽  
Author(s):  
Dean N. Edun ◽  
Meredith R. Flanagan ◽  
Arnaldo L. Serrano
Keyword(s):  
Infrared Spectroscopy ◽  
Phase Separation ◽  
Liquid Phase ◽  
Model Membrane ◽  
Peptide Folding ◽  
Two Dimensional ◽  
Intrinsically Disordered ◽  
Intrinsically Disordered Peptide ◽  
Two Dimensional Infrared Spectroscopy ◽  
Liquid Liquid Phase Separation

Two-dimensional infrared spectroscopy reveals folding of an intrinsically disordered peptide when sequestered into a model “membrane-less” organelle.

LATTICE SIMULATION OF NASCENT PEPTIDE FOLDING

2004 ◽  
Vol 18 (15) ◽  
pp. 2195-2202 ◽  
Author(s):  
JIAFENG ZHUO ◽  
LINSEN ZHANG ◽  
CHANGJUN CHEN ◽  
YI HE ◽  
YI XIAO
Keyword(s):  
Lattice Model ◽  
Peptide Folding ◽  
Synthesis Process ◽  
Lattice Simulation ◽  
Native State ◽  
Second Stage ◽  
Nascent Peptide ◽  
Two Stages

The nascent peptide folding in vivo is different from the denatured peptide refolding in vitro and can be divided into two stages. In the first stage, the peptide is folding as it is being synthesized until the whole peptide chain is synthesized. The final conformation formed in this stage is called as nascent state. In the second stage, the protein folds beginning with the nascent state formed in the first stage into the native state. We use a lattice model to simulate these two stages and investigate the folding time of the nascent peptide comparing with that of the denatured peptide refolding. Our results show that the synthesis process may affect the folding time of the nascent peptide. This may be helpful to understand why the former folds faster than the latter.

scholarly journals Infrared Photoactivation Reduces Peptide Folding and Hydrogen-Atom Migration following ETD Tandem Mass Spectrometry

2009 ◽  
Vol 48 (45) ◽  
pp. 8526-8528 ◽  
Author(s):  
Aaron R. Ledvina ◽  
Graeme C. McAlister ◽  
Myles W. Gardner ◽  
Suncerae I. Smith ◽  
James A. Madsen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Hydrogen Atom ◽  
Tandem Mass Spectrometry ◽  
Peptide Folding ◽  
Tandem Mass ◽  
Atom Migration

Solvent Electrostriction-Driven Peptide Folding Revealed by Quasi-Gaussian Entropy Theory and Molecular Dynamics Simulation

2008 ◽  
Vol 112 (35) ◽  
pp. 11155-11163 ◽  
Author(s):  
Frank Noé ◽  
Isabella Daidone ◽  
Jeremy C. Smith ◽  
Alfredo di Nola ◽  
Andrea Amadei
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulation ◽  
Peptide Folding ◽  
Dynamics Simulation ◽  
Entropy Theory
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