Development of Robust Heterogeneous Chiral Rhodium Catalysts Utilizing Acid–Base and Electrostatic Interactions for Efficient Continuous-Flow Asymmetric Hydrogenations

2020 ◽  
Vol 142 (39) ◽  
pp. 16546-16551
Author(s):  
Yuki Saito ◽  
Shu̅ Kobayashi
Keyword(s):  
Continuous Flow ◽  
Electrostatic Interactions ◽  
Rhodium Catalysts ◽  
Acid Base ◽  
Chiral Rhodium Catalysts ◽  
Asymmetric Hydrogenations

A potentiometric study of the effects of molecular complexing on acid–base equilibria

1976 ◽  
Vol 54 (13) ◽  
pp. 2141-2153 ◽  
Author(s):  
A. K. Colter ◽  
D. Buben
Keyword(s):  
Electrostatic Interactions ◽  
Potentiometric Method ◽  
Acidity Constant ◽  
Complexation Constants ◽  
Acid Base ◽  
Acid Complex ◽  
Molecular Complexation ◽  
Opposing Effects ◽  
Conjugate Base ◽  
Sufficient Precision

The effect of molecular complexing on several acid–base equilibria involving organic π donor acids has been studied by a potentiometric method. The method leads to complexation constants for the acceptor with the donor acid and its conjugate base. In several cases the two association constants can be determined with sufficient precision to obtain an estimate of the acidity constant for the 1:1 acceptor–donor acid complex. In all situations where charge-transfer and electrostatic interactions are expected to have opposing effects on the acidity, electrostatic effects dominate. The range of the validity and usefulness of the potentiometric method in studies of molecular complexation equilibria is discussed, together with the results obtained in this work.

Electrostatic Interactions between Acid-/Base-Containing Polymer Nanoparticles and Proteins: Impact of Polymerization pH

2020 ◽  
Vol 3 (6) ◽  
pp. 3827-3834 ◽  
Author(s):  
Ryutaro Honda ◽  
Tomohiro Gyobu ◽  
Hideto Shimahara ◽  
Yoshiko Miura ◽  
Yu Hoshino
Keyword(s):  
Electrostatic Interactions ◽  
Polymer Nanoparticles ◽  
Acid Base

Chiral Rhodium Catalysts

2011 ◽  
pp. 1
Author(s):  
G. -J. Jiang ◽  
Y. Wang ◽  
Z. -X. Yu
Keyword(s):  
Rhodium Catalysts ◽  
Chiral Rhodium Catalysts

scholarly journals Continuous-flow catalytic asymmetric hydrogenations: Reaction optimization using FTIR inline analysis

2012 ◽  
Vol 8 ◽  
pp. 300-307 ◽  
Author(s):  
Magnus Rueping ◽  
Teerawut Bootwicha ◽  
Erli Sugiono
Keyword(s):  
Continuous Flow ◽  
Flow Cell ◽  
Reaction Monitoring ◽  
Reaction Parameters ◽  
Reaction Optimization ◽  
Catalytic Asymmetric ◽  
Asymmetric Hydrogenations ◽  
High Yields ◽  
Flow Microreactors

The asymmetric organocatalytic hydrogenation of benzoxazines, quinolines, quinoxalines and 3H-indoles in continuous-flow microreactors has been developed. Reaction monitoring was achieved by using an inline ReactIR flow cell, which allows fast and convenient optimization of reaction parameters. The reductions proceeded well, and the desired products were isolated in high yields and with excellent enantioselectivities.

Practical Synthesis of Optically Active Styrene Oxides via Reductive Transformation of 2-Chloroacetophenones with Chiral Rhodium Catalysts

2002 ◽  
Vol 4 (24) ◽  
pp. 4373-4376 ◽  
Author(s):  
Takayuki Hamada ◽  
Takayoshi Torii ◽  
Kunisuke Izawa ◽  
Ryoji Noyori ◽  
Takao Ikariya
Keyword(s):  
Optically Active ◽  
Rhodium Catalysts ◽  
Reductive Transformation ◽  
Chiral Rhodium Catalysts ◽  
Practical Synthesis

Diastereoselective deuteration of (Z)-α,β-dehydrotryptophanyl-containing biological peptides controlled by chiral rhodium catalysts

1998 ◽  
Vol 39 (19) ◽  
pp. 2955-2958 ◽  
Author(s):  
Akli Hammadi ◽  
Gilles Meunier ◽  
André Ménez ◽  
Roger Genet
Keyword(s):  
Rhodium Catalysts ◽  
Chiral Rhodium Catalysts
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