Asymmetric Conjugate Reduction of α,β-Unsaturated Esters Using a Chiral Phosphine−Copper Catalyst

1999 ◽  
Vol 121 (40) ◽  
pp. 9473-9474 ◽  
Author(s):  
Daniel H. Appella ◽  
Yasunori Moritani ◽  
Ryo Shintani ◽  
Eric M. Ferreira ◽  
Stephen L. Buchwald
Keyword(s):  
Copper Catalyst ◽  
Unsaturated Esters ◽  
Conjugate Reduction

ChemInform Abstract: Asymmetric Conjugate Reduction of α,β-Unsaturated Esters Using a Chiral Phosphine-Copper Catalyst.

ChemInform ◽  
2010 ◽  
Vol 31 (4) ◽  
pp. no-no
Author(s):  
Daniel H. Appella ◽  
Yasunori Moritani ◽  
Ryo Shintani ◽  
Eric M. Ferreira ◽  
Stephen L. Buchwald
Keyword(s):  
Copper Catalyst ◽  
Unsaturated Esters ◽  
Conjugate Reduction

scholarly journals Copper-catalyzed enantioselective conjugate reduction of α,β-unsaturated esters with chiral phenol–carbene ligands

2020 ◽  
Vol 16 ◽  
pp. 537-543
Author(s):  
Shohei Mimura ◽  
Sho Mizushima ◽  
Yohei Shimizu ◽  
Masaya Sawamura
Keyword(s):  
Critical Role ◽  
Enantiomeric Excess ◽  
Carbene Ligands ◽  
Unsaturated Esters ◽  
Conjugate Reduction ◽  
Phenol Moiety

A chiral phenol–NHC ligand enabled the copper-catalyzed enantioselective conjugate reduction of α,β-unsaturated esters. The phenol moiety of the chiral NHC ligand played a critical role in producing the enantiomerically enriched products. The catalyst worked well for various (Z)-isomer substrates. Opposite enantiomers were obtained from (Z)- and (E)-isomers, with a higher enantiomeric excess from the (Z)-isomer.

Asymmetric Conjugate Reduction of ?,?-Unsaturated Esters with Chiral Rhodium(bisoxazolinylphenyl) Catalysts.

ChemInform ◽  
2005 ◽  
Vol 36 (17) ◽  
Author(s):  
Yasunori Tsuchiya ◽  
Yoshinori Kanazawa ◽  
Takushi Shiomi ◽  
Kazuki Kobayashi ◽  
Hisao Nishiyama
Keyword(s):  
Unsaturated Esters ◽  
Conjugate Reduction

Chemoselective Conjugate Reduction of α,β-Unsaturated Esters and Lactones Under Mild Conditions

Synlett ◽  
1991 ◽  
Vol 1991 (11) ◽  
pp. 825-826 ◽  
Author(s):  
J. Cristóbal López ◽  
Ana M. Gómez ◽  
Serafín Valverde
Keyword(s):  
Unsaturated Esters ◽  
Mild Conditions ◽  
Conjugate Reduction
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