Biosynthetic Studies on the α-Glucosidase Inhibitor Acarbose inActinoplanessp.:  2-epi-5-epi-Valiolone Is the Direct Precursor of the Valienamine Moiety

Taifo Mahmud; Ingo Tornus; Erin Egelkrout; Eckardt Wolf; Charmaine Uy; Heinz G. Floss; Sungsook Lee

doi:10.1021/ja991102w

Biosynthetic Studies on the α-Glucosidase Inhibitor Acarbose inActinoplanessp.: 2-epi-5-epi-Valiolone Is the Direct Precursor of the Valienamine Moiety

Journal of the American Chemical Society ◽

10.1021/ja991102w ◽

1999 ◽

Vol 121 (30) ◽

pp. 6973-6983 ◽

Cited By ~ 43

Author(s):

Taifo Mahmud ◽

Ingo Tornus ◽

Erin Egelkrout ◽

Eckardt Wolf ◽

Charmaine Uy ◽

...

Keyword(s):

Glucosidase Inhibitor ◽

Biosynthetic Studies

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Biosynthetic Studies on the .ALPHA.-Glucosidase Inhibitor Acarbose in Actinoplanes sp.: Glutamate is the Primary Source of the Nitrogen in Acarbose.

The Journal of Antibiotics ◽

10.7164/antibiotics.51.225 ◽

1998 ◽

Vol 51 (2) ◽

pp. 225-227 ◽

Cited By ~ 7

Author(s):

SUNGSOOK LEE ◽

ERIN EGELKROUT

Keyword(s):

Primary Source ◽

Glucosidase Inhibitor ◽

Biosynthetic Studies ◽

Alpha Glucosidase

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Biosynthetic studies on the α-glucosidase inhibitor acarbose: the chemical synthesis of isotopically labeled 2-epi-5-epi-valiolone analogs

Carbohydrate Research ◽

10.1016/s0008-6215(03)00315-x ◽

2003 ◽

Vol 338 (20) ◽

pp. 2075-2082 ◽

Cited By ~ 12

Author(s):

Kenji Arakawa ◽

Simeon G Bowers ◽

Benjamin Michels ◽

Vu Trin ◽

Taifo Mahmud

Keyword(s):

Chemical Synthesis ◽

Glucosidase Inhibitor ◽

Biosynthetic Studies

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Biosynthetic studies on the α-glucosidase inhibitor acarbose: the chemical synthesis of dTDP-4-amino-4,6-dideoxy-α-d-glucose

Carbohydrate Research ◽

10.1016/s0008-6215(01)00323-8 ◽

2002 ◽

Vol 337 (4) ◽

pp. 297-304 ◽

Cited By ~ 14

Author(s):

Simeon G. Bowers ◽

Taifo Mahmud ◽

Heinz G. Floss

Keyword(s):

Chemical Synthesis ◽

Glucosidase Inhibitor ◽

Biosynthetic Studies

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Miglitol, an α-Glucosidase Inhibitor, Prevents the Metformin-Induced Fall in Serum Folate and Vitamin B12 in Subjects with Type 2 Diabetes

Nutrition Research ◽

10.1016/s0271-5317(00)00228-1 ◽

2000 ◽

Vol 20 (10) ◽

pp. 1505-1511

Author(s):

T Wolever

Keyword(s):

Type 2 Diabetes ◽

Vitamin B12 ◽

Serum Folate ◽

Glucosidase Inhibitor ◽

Folate And Vitamin B12

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α-amylase and α-glucosidase inhibitor activities of secondary metabolites from Arcytophyllum thymifolium

Planta Medica ◽

10.1055/s-0036-1596498 ◽

2016 ◽

Vol 81 (S 01) ◽

pp. S1-S381

Author(s):

M De Leo ◽

A Braca ◽

MB Vera Saltos ◽

I Faraone ◽

N Malafronte ◽

...

Keyword(s):

Secondary Metabolites ◽

Glucosidase Inhibitor

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Biosynthetic studies on ambelline and tazettine

10.31274/rtd-180815-463 ◽

1966 ◽

Author(s):

John Arthur Miller

Keyword(s):

Biosynthetic Studies

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Faculty Opinions recommendation of Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726431135.793520208 ◽

2016 ◽

Author(s):

Steven Austad

Keyword(s):

Male Mice ◽

Glucosidase Inhibitor

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Free Energy Perturbation Calculations on Glucosidase-Inhibitor Complexes

Medicinal Chemistry ◽

10.2174/1573406054864151 ◽

2005 ◽

Vol 1 (5) ◽

pp. 455-460 ◽

Cited By ~ 4

Author(s):

F. Ruiz ◽

J. Grigera

Keyword(s):

Free Energy ◽

Free Energy Perturbation ◽

Glucosidase Inhibitor ◽

Energy Perturbation

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Reduced postprandial bone resorption and greater rise in GLP-1 in overweight and obese individuals after an α-glucosidase inhibitor: a double-blinded randomized crossover trial

Osteoporosis International ◽

10.1007/s00198-020-05791-5 ◽

2021 ◽

Author(s):

A. Kreitman ◽

S. H. Schneider ◽

L. Hao ◽

Y. Schlussel ◽

N. T. Bello ◽

...

Keyword(s):

Bone Resorption ◽

Crossover Trial ◽

Glucosidase Inhibitor ◽

Randomized Crossover Trial ◽

Double Blinded

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Correction to: A novel series of mixed-ligand M(II) complexes containing 2,2′-bipyridyl as potent α-glucosidase inhibitor: synthesis, crystal structure, DFT calculations, and molecular docking

JBIC Journal of Biological Inorganic Chemistry ◽

10.1007/s00775-021-01880-w ◽

2021 ◽

Author(s):

Davut Avcı ◽

Sümeyye Altürk ◽

Fatih Sönmez ◽

Ömer Tamer ◽

Adil Başoğlu ◽

...

Keyword(s):

Crystal Structure ◽

Molecular Docking ◽

Dft Calculations ◽

Mixed Ligand ◽

Glucosidase Inhibitor

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