α Hydroxylation of Carboxylic Acids with Molecular Oxygen Catalyzed by the α Oxidase of Peas (Pisumsativum):  A Novel Biocatalytic Synthesis of Enantiomerically Pure (R)-2-Hydroxy Acids

1998 ◽  
Vol 120 (43) ◽  
pp. 11044-11048 ◽  
Author(s):  
Waldemar Adam ◽  
Wilhelm Boland ◽  
Jenny Hartmann-Schreier ◽  
Hans-Ulrich Humpf ◽  
Michael Lazarus ◽  
...  
Keyword(s):  
Molecular Oxygen ◽  
Carboxylic Acids ◽  
Hydroxy Acids ◽  
Enantiomerically Pure

The reaction of carboxylic acids with epoxides using lithium naphthalenide

1974 ◽  
Vol 27 (10) ◽  
pp. 2205 ◽  
Author(s):  
T Fujita ◽  
S Watanabe ◽  
K Suga
Keyword(s):  
Carboxylic Acids ◽  
Good Yield ◽  
Hydroxy Acids

Lithium naphthalenide reacts with carboxylic acids in the presence of diethylamine to give the α-anions of lithium carboxylates. Reaction of these anions with various epoxides gives the corresponding y-hydroxy acids in good yield. The γ-hydroxy acids easily cyclize to give γ-butyrolactones.

ChemInform Abstract: Oxidation of Aldehydes into Carboxylic Acids with Molecular Oxygen Using Nickel(II) Complex Catalyst.

ChemInform ◽  
2010 ◽  
Vol 23 (44) ◽  
pp. no-no ◽  
Author(s):  
T. YAMADA ◽  
O. RHODE ◽  
T. TAKAI ◽  
T. MUKAIYAMA
Keyword(s):  
Molecular Oxygen ◽  
Carboxylic Acids ◽  
Complex Catalyst

scholarly journals Copper mediated decarboxylative direct C–H arylation of heteroarenes with benzoic acids

2016 ◽  
Vol 52 (7) ◽  
pp. 1432-1435 ◽  
Author(s):  
Tuhin Patra ◽  
Sudip Nandi ◽  
Santosh K. Sahoo ◽  
Debabrata Maiti
Keyword(s):  
Molecular Oxygen ◽  
Carboxylic Acids ◽  
Dual Role ◽  
Benzoic Acids

Copper mediated decarboxylative direct C–H arylation of 5-membered heteroarenes with aryl carboxylic acids is developed using the molecular oxygen as sole oxidant. Copper plays the dual role in decarboxylation and C–H arylation.

scholarly journals The Messy Alkaline Formose Reaction and Its Link to Metabolism

Life ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 125
Author(s):  
Arthur Omran ◽  
Cesar Menor-Salvan ◽  
Greg Springsteen ◽  
Matthew Pasek
Keyword(s):  
Carboxylic Acids ◽  
Food Source ◽  
Chemical Species ◽  
Origins Of Life ◽  
Hydroxy Acids ◽  
Genetic Elements ◽  
Formose Reaction ◽  
Alkaline Conditions

Sugars are essential for the formation of genetic elements such as RNA and as an energy/food source. Thus, the formose reaction, which autocatalytically generates a multitude of sugars from formaldehyde, has been viewed as a potentially important prebiotic source of biomolecules at the origins of life. When analyzing our formose solutions we find that many of the chemical species are simple carboxylic acids, including α-hydroxy acids, associated with metabolism. In this work we posit that the study of the formose reaction, under alkaline conditions and moderate hydrothermal temperatures, should not be solely focused on sugars for genetic materials, but should focus on the origins of metabolism (via metabolic molecules) as well.

Chiroptical sensing of unprotected amino acids, hydroxy acids, amino alcohols, amines and carboxylic acids with metal salts

2019 ◽  
Vol 55 (44) ◽  
pp. 6297-6300 ◽  
Author(s):  
Ciarán C. Lynch ◽  
Zeus A. De los Santos ◽  
Christian Wolf
Keyword(s):  
Amino Acids ◽  
Carboxylic Acids ◽  
Amino Alcohols ◽  
Metal Salts ◽  
Hydroxy Acids ◽  
Optical Chirality ◽  
Iron Palladium

Optical chirality sensing of unprotected amino acids, hydroxy acids, amino alcohols, amines and carboxylic acids based on a practical mix-and-measure protocol with readily available copper, iron, palladium, manganese, cerium or rhodium salts is demonstrated.

Synthesis of novel chiral fluorescent sensors and their application in enantioselective discrimination of chiral carboxylic acids

2019 ◽  
Vol 43 (9-10) ◽  
pp. 340-346 ◽  
Author(s):  
Qiuhan Yu ◽  
Weiwen Lu ◽  
Zhiqiang Ding ◽  
Min Wei ◽  
Zhenya Dai
Keyword(s):  
Carboxylic Acids ◽  
Chiral Recognition ◽  
Amino Alcohols ◽  
Fluorescent Sensors ◽  
Enantiomerically Pure ◽  
Wide Range

Novel chiral fluorescent sensors are synthesized from a dibromide containing a tetraphenylethylene moiety and enantiomerically pure amino alcohols and an amine. The sensors are applied for the chiral recognition of a wide range of chiral carboxylic acids and related derivatives.

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