Using the Electrostatic Field Effect to Design a New Class of Inhibitors for Cysteine Proteases

1997 ◽  
Vol 119 (18) ◽  
pp. 4285-4291 ◽  
Author(s):  
Jeffrey L. Conroy ◽  
Tanya C. Sanders ◽  
Christopher T. Seto
Keyword(s):  
Electrostatic Field ◽  
Field Effect ◽  
Cysteine Proteases ◽  
New Class

N.M.R. spectra and stereochemistry of the bipyridyls. III. 2,2'-Bipyridyl and dimethyl derivatives, 3,3'- bipyridyl, and 4,4' - bipyridyl

1967 ◽  
Vol 20 (6) ◽  
pp. 1227 ◽  
Author(s):  
TM Spotswood ◽  
CI Tanzer
Keyword(s):  
Hydrogen Bonding ◽  
Electrostatic Field ◽  
Field Effect ◽  
Chemical Shifts ◽  
Lone Pair ◽  
Diamagnetic Anisotropy ◽  
Equal Importance ◽  
Nitrogen Lone Pair ◽  
Lone Pair Electrons ◽  
Derivatives Of

The analysis of the n.m.r, spectra of 2,2?-, 3,3?-, and 4,4?-bipyridyl and three dimethyl-2,2?-bipyridyls is reported and the factors determining the relative chemical shifts of the ring protons and methyl groups in several solvents are discussed. The diamagnetic anisotropy of the neighbouring ring and electrostatic field effect of the nitrogen lone pair electrons are shown to be of roughly equal importance for derivatives of 2,2?-bipyridyl except in hydrogen bonding solvents. Attenuation of the electrostatic field effect in polar, and particularly in hydrogen bonding solvents, is established for 4- picoline, and for the bipyridyls, and this effect is responsible for striking changes in the spectrum of 2,2?-bipyridyl in hydrogen bonding solvents. An approximate interplanar angle of 58� is derived for 3,3?- dimethyl-2,2?-bipyridyl, and 2,2?-bipyridyl and its 4,4?- and 5,5?- dimethyl derivatives appear to be trans coplanar in all solvents. 3,3?- Bipyridyl and 4,4?-bipyridyl are probably highly twisted in all solvents, or alternatively, behave as essentially free rotors. The predicted conformations are in good agreement with the electronic spectral data.

scholarly journals Graphene–Si CMOS oscillators

Nanoscale ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 3619-3625 ◽  
Author(s):  
Carlo Gilardi ◽  
Paolo Pedrinazzi ◽  
Kishan Ashokbhai Patel ◽  
Luca Anzi ◽  
Birong Luo ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
New Class ◽  
Graphene Field Effect Transistor ◽  
Cmos Oscillators ◽  
Effect Transistor ◽  
Electronic Oscillators

The ambipolarity of graphene is exploited to realize a new class of electronic oscillators by integrating a graphene field-effect transistor with Si CMOS logic.

scholarly journals Aza-Peptide Epoxides: A New Class of Inhibitors Selective for Clan CD Cysteine Proteases

ChemInform ◽  
2003 ◽  
Vol 34 (3) ◽  
Author(s):  
Juliana L. Asgian ◽  
Karen Ellis James ◽  
Zhao Zhao Li ◽  
Wendy Carter ◽  
Alan J. Barrett ◽  
...  
Keyword(s):  
Cysteine Proteases ◽  
New Class

scholarly journals Formation of Nonwoven Webs with Electrostatic Field Effect

2020 ◽  
Vol 23 (1) ◽  
pp. 30-34
Author(s):  
Ahmad S. Kanah ◽  
Mohamed Turkawi
Keyword(s):  
Electric Field ◽  
Polyvinyl Alcohol ◽  
Electrostatic Field ◽  
Field Effect ◽  
Effective Surface ◽  
High Productivity ◽  
Nonwoven Materials ◽  
The World ◽  
Polymeric Solutions ◽  
Electrode Plate

The non-woven materials industry is one of the fastest-growing industries in the world with the ability to produce materials in less time, specifications, and better prices. nonwoven materials are defined as a web of guided or random fibers that are bonded by friction, interlacement or adhesion. In this research, the rotary electrospinning system was used and a prototype was made to study the process and the complete visualization in terms of the correlation of the electrostatic forces to the formation of nanofibers  by preparing polymeric solutions and exposing them to the electric field between the positive electrode (the serrated cylinder) and the Grounded electrode (plate) and produced high-precision fibers with a diameter (185nm) at 25 kV, whereas the installation of polyvinyl alcohol (PVA) was with different concentrations and the formed fibers possessed an effective surface and deposited on a collector electrode forming nonwoven webs and high productivity is the most important feature of this system compared with the traditional electrospinning system.

scholarly journals Electrostatic Field Effect Light-Emitting Diode

2020 ◽  
Vol 12 (3) ◽  
pp. 1-8 ◽  
Author(s):  
Matthew Hartensveld ◽  
Bryan Melanson ◽  
Jing Zhang
Keyword(s):  
Electrostatic Field ◽  
Field Effect ◽  
Light Emitting Diode ◽  
Light Emitting
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