EPR Evidence for a Tyrosyl Radical Intermediate in Bovine Liver Catalase

1996 ◽  
Vol 118 (50) ◽  
pp. 12852-12853 ◽  
Author(s):  
Anabella Ivancich ◽  
Hélène Marie Jouve ◽  
Jacques Gaillard
Keyword(s):  
Bovine Liver ◽  
Tyrosyl Radical ◽  
Radical Intermediate ◽  
Bovine Liver Catalase

scholarly journals Polarized proton spin density images the tyrosyl radical locations in bovine liver catalase

IUCrJ ◽  
2016 ◽  
Vol 3 (5) ◽  
pp. 326-340 ◽  
Author(s):  
Oliver Zimmer ◽  
Hélène M. Jouve ◽  
Heinrich B. Stuhrmann
Keyword(s):  
Neutron Scattering ◽  
Scattering Amplitude ◽  
Bovine Liver ◽  
Proton Spin ◽  
Tyrosyl Radical ◽  
Nuclear Scattering ◽  
Bovine Liver Catalase ◽  
Radical State ◽  
Polarized Neutron ◽  
Polarized Neutron Scattering

A tyrosyl radical, as part of the amino acid chain of bovine liver catalase, supports dynamic proton spin polarization (DNP). Finding the position of the tyrosyl radical within the macromolecule relies on the accumulation of proton polarization close to it, which is readily observed by polarized neutron scattering. The nuclear scattering amplitude due to the polarization of protons less than 10 Å distant from the tyrosyl radical is ten times larger than the amplitude of magnetic neutron scattering from an unpaired polarized electron of the same radical. The direction of DNP was inverted every 5 s, and the initial evolution of the intensity of polarized neutron scattering after each inversion was used to identify those tyrosines which have assumed a radical state. Three radical sites, all of them close to the molecular centre and the haem, appear to be equally possible. Among these is tyr-369, the radical state of which had previously been proven by electron paramagnetic resonance.

The molecular symmetry of bovine liver catalase

1975 ◽  
Vol 93 (1) ◽  
pp. 55-62 ◽  
Author(s):  
William Eventoff ◽  
G.V. Gurskaya
Keyword(s):  
Bovine Liver ◽  
Molecular Symmetry ◽  
Bovine Liver Catalase

Molecular docking and inhibitory effects of a novel cytotoxic agent with bovine liver catalase

2020 ◽  
Vol 1205 ◽  
pp. 127590
Author(s):  
Somaye Shahraki ◽  
Maryam Saeidifar ◽  
Hojat Samareh Delarami ◽  
Houman Kazemzadeh
Keyword(s):  
Molecular Docking ◽  
Bovine Liver ◽  
Cytotoxic Agent ◽  
Inhibitory Effects ◽  
Bovine Liver Catalase
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